ML 141 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemML 141
CompanyTocris Bioscience, a Bio-Techne Brand
Price $280.00Supplier Page View Company Product Page
Catalog Number4266/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight407.49
Molecule Name4-[4,5-Dihydro-5-(4-methoxyphenyl)-3-phenyl-1H-pyrazol-1-yl]benzenesulfonamide
FormulaC22H21N3O3S
StorageStore at +4°C

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Identification of a pharmacological approach to reduce ACE2 expression and development of an in vitro COVID-19 viral entry modelJournal of virus eradicationDecember 1, 2022Endo Y, Hickerson BT, Ilyushina NA, Mohan N, Peng H, Takeda K, Donnelly RP, Wu WJ.

(2) Local changes in microtubule network mobility instruct neuronal polarization and axon specificationScience advancesNovember 4, 2022Burute M, Jansen KI, Mihajlovic M, Vermonden T, Kapitein LC.

(3) Caveolae couple mechanical stress to integrin recycling and activationeLifeOctober 20, 2022Lolo FN, Pavón DM, Grande A, Elósegui Artola A, Segatori VI, Sánchez S, Trepat X, Roca-Cusachs P, Del Pozo MA.

(4) The Process of Filopodia Induction during HPV InfectionVirusesMay 26, 2022Biondo A, Meneses PI.

(5) Statin-mediated disruption of Rho GTPase prenylation and activity inhibits respiratory syncytial virus infectionCommunications biologyOctober 29, 2021Malhi M, Norris MJ, Duan W, Moraes TJ, Maynes JT.

(6) FBP17-mediated finger-like membrane protrusions in cell competition between normal and RasV12-transformed cellsiScienceSeptember 24, 2021Kamasaki T, Miyazaki Y, Ishikawa S, Hoshiba K, Kuromiya K, Tanimura N, Mori Y, Tsutsumi M, Nemoto T, Uehara R, et al.

(7) Wnt5a modulates dendritic spine dynamics through the regulation of Cofilin via small Rho GTPase activity in hippocampal neuronsJournal of neurochemistryAugust 1, 2021Vallejo D, Lindsay CB, González-Billault C, Inestrosa NC.

(8) Zc3h10 regulates adipogenesis by controlling translation and F-actin/mitochondria interactionThe Journal of cell biologyMarch 1, 2021Audano M, Pedretti S, Ligorio S, Gualdrini F, Polletti S, Russo M, Ghisletti S, Bean C, Crestani M, Caruso D, et al.

(9) Concerted regulation of actin polymerization during constitutive secretion by cortactin and PKD2Journal of cell scienceDecember 13, 2019Weeber F, Becher A, Seibold T, Seufferlein T, Eiseler T.

(10) A Non-canonical Pathway with Potential for Safer Modulation of Transforming Growth Factor-β1 in Steroid-Resistant Airway DiseasesiScienceFebruary 22, 2019Li M, Keenan CR, Lopez-Campos G, Mangum JE, Chen Q, Prodanovic D, Xia YC, Langenbach SY, Harris T, Hofferek V, et al.

(11) Identification of DKK-1 as a novel mediator of statin effects in human endothelial cellsScientific reportsNovember 12, 2018Pontremoli M, Brioschi M, Baetta R, Ghilardi S, Banfi C.

(12) Mechanochemical feedback control of dynamin independent endocytosis modulates membrane tension in adherent cellsNature communicationsOctober 11, 2018Thottacherry JJ, Kosmalska AJ, Kumar A, Vishen AS, Elosegui-Artola A, Pradhan S, Sharma S, Singh PP, Guadamillas MC, Chaudhary N, et al.

(13) FBP17 and CIP4 recruit SHIP2 and lamellipodin to prime the plasma membrane for fast endophilin-mediated endocytosisNature cell biologySeptember 1, 2018Chan Wah Hak L, Khan S, Di Meglio I, Law AL, Lucken-Ardjomande Häsler S, Quintaneiro LM, Ferreira APA, Krause M, McMahon HT, Boucrot E.

(14) Cdc42 controls primary mesenchyme cell morphogenesis in the sea urchin embryoDevelopmental biologyMay 15, 2018Sepúlveda-Ramírez SP, Toledo-Jacobo L, Henson JH, Shuster CB.

(15) Chlamydia exploits filopodial capture and a macropinocytosis-like pathway for host cell entryPLoS pathogensMay 1, 2018Ford C, Nans A, Boucrot E, Hayward RD.

(16) Cdc42 activation couples fluid shear stress to apical endocytosis in proximal tubule cellsPhysiological ReportsOctober 16, 2017Sohinee Bhattacharyya, Frédéric G. Jean-Alphonse, Venkatesan Raghavan, Jennifer C. McGarvey, Youssef Rbaibi, Jean-Pierre Vilardaga, Marcelo D. Carattino, Ora A. Weiszexperiments. For FRET and endocytosis experiments, cells were pretreated with drugs [ML141 (Tocris‐4266, 10 μmol/L); Calp3 (Tocris‐2321, 5 μmol/L; ryanodine (Tocris‐1329, 25 μmol/L), or W13 (Tocris‐0361, 60 μmol/L),

(17) GOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edgeMolecular biology of the cellDecember 1, 2016Xing M, Peterman MC, Davis RL, Oegema K, Shiau AK, Field SJ.

(18) Human metapneumovirus Induces Reorganization of the Actin Cytoskeleton for Direct Cell-to-Cell SpreadPLoS pathogensSeptember 1, 2016El Najjar F, Cifuentes-Muñoz N, Chen J, Zhu H, Buchholz UJ, Moncman CL, Dutch RE.

(19) Competition for actin between two distinct F-actin networks defines a bistable switch for cell polarizationNature cell biologyNovember 1, 2015Lomakin AJ, Lee KC, Han SJ, Bui DA, Davidson M, Mogilner A, Danuser G.

(20) Dynasore disrupts trafficking of herpes simplex virus proteinsJournal of virologyJuly 1, 2015Mues MB, Cheshenko N, Wilson DW, Gunther-Cummins L, Herold BC.

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ML 141

ML 141 from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

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ML 141 from Tocris Bioscience, a Bio-Techne Brand

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