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HC 030031
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HC 030031
Selective TRPA1 blocker
HC 030031 from Tocris Bioscience, a Bio-Techne Brand
Be the first to write a review!
Citations:
(33)
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Tocris Bioscience, a Bio-Techne Brand for
HC 030031
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Description
Selective TRPA1 blocker
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
HC 030031
Company
Tocris Bioscience, a Bio-Techne Brand
Price
$201.00
Supplier Page
View Company Product Page
Catalog Number
2896/10
Quantity
10 mg (also 50 mg)
Purity
98%
Molecular Weight
355.39
Molecule Name
2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide
Formula
C18H21N5O3
Storage
Store at RT
Specifications/Features
Sizes Available:
10 mg (also 50 mg)
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Tocris Bioscience, a Bio-Techne Brand
614 McKinley Place N.E.
Minneapolis
,
Minnesota
55413
United States
Phone
: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400
Company Profile
Website:
http://www.tocris.com
Citations (33)
(1)
A critical evaluation of TRPA1-mediated locomotor behavior in zebrafish as a screening tool for novel anti-nociceptive drug discovery
Scientific reports
February 20, 2019
Ko MJ, Ganzen LC, Coskun E, Mukadam AA, Leung YF, van Rijn RM.
(2)
Bladder Dysfunction in an Obese Zucker Rat: The Role of TRPA1 Channels, Oxidative Stress, and Hydrogen Sulfide
Oxidative medicine and cellular longevity
January 1, 2019
Blaha I, López-Oliva ME, Martínez MP, Recio P, Agis-Torres Á, Martínez AC, Benedito S, García-Sacristán A, Prieto D, Fernandes VS,
et al
.
(3)
The role of Na
v
1.7 and methylglyoxal-mediated activation of TRPA1 in itch and hypoalgesia in a murine model of type 1 diabetes
Theranostics
January 1, 2019
Cheng RX, Feng Y, Liu D, Wang ZH, Zhang JT, Chen LH, Su CJ, Wang B, Huang Y, Ji RR,
et al
.
(4)
Relevance of TRPA1 and TRPM8 channels as vascular sensors of cold in the cutaneous microvasculature
Pflugers Archiv : European journal of physiology
May 1, 2018
Pan Y, Thapa D, Baldissera L Jr, Argunhan F, Aubdool AA, Brain SD.
(5)
TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p
Nature communications
October 16, 2017
Berrout J, Kyriakopoulou E, Moparthi L, Hogea AS, Berrout L, Ivan C, Lorger M, Boyle J, Peers C, Muench S,
et al
.
(6)
Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes
Neuron
February 8, 2017
Agarwal A, Wu PH, Hughes EG, Fukaya M, Tischfield MA, Langseth AJ, Wirtz D, Bergles DE.
(7)
Methylglyoxal Requires AC1 and TRPA1 to Produce Pain and Spinal Neuron Activation
Frontiers in neuroscience
January 1, 2017
Griggs RB, Laird DE, Donahue RR, Fu W, Taylor BK.
(8)
Effects of ε-viniferin, a dehydrodimer of resveratrol, on transepithelial active ion transport and ion permeability in the rat small and large intestinal mucosa
Physiological reports
May 1, 2016
Karaki S, Ishikawa J, Tomizawa Y, Kuwahara A.
(9)
Environmental cold exposure increases blood flow and affects pain sensitivity in the knee joints of CFA-induced arthritic mice in a TRPA1-dependent manner
Arthritis research & therapy
January 11, 2016
Fernandes ES, Russell FA, Alawi KM, Sand C, Liang L, Salamon R, Bodkin JV, Aubdool AA, Arno M, Gentry C,
et al
.
(10)
Modulation of breast cancer cell viability by a cannabinoid receptor 2 agonist, JWH-015, is calcium dependent
Breast cancer (Dove Medical Press)
January 1, 2016
Hanlon KE, Lozano-Ondoua AN, Umaretiya PJ, Symons-Liguori AM, Chandramouli A, Moy JK, Kwass WK, Mantyh PW, Nelson MA, Vanderah TW.
(11)
Hydrogen sulfide-induced itch requires activation of Cav3.2 T-type calcium channel in mice
Scientific reports
November 25, 2015
Wang XL, Tian B, Huang Y, Peng XY, Chen LH, Li JC, Liu T.
(12)
Released lipids regulate transient receptor potential channel (TRP)-dependent oral cancer pain
Molecular pain
May 26, 2015
Ruparel S, Bendele M, Wallace A, Green D.
(13)
Alterations in serotonin, transient receptor potential channels and protease-activated receptors in rats with irritable bowel syndrome attenuated by Shugan decoction
World journal of gastroenterology
April 28, 2015
Shi HL, Liu CH, Ding LL, Zheng Y, Fei XY, Lu L, Zhou XM, Yuan JY, Xie JQ.
(14)
Structure of the TRPA1 ion channel suggests regulatory mechanisms
Nature
April 23, 2015
Paulsen CE, Armache JP, Gao Y, Cheng Y, Julius D.
(15)
Antinociceptive activity of transient receptor potential channel TRPV1, TRPA1, and TRPM8 antagonists in neurogenic and neuropathic pain models in mice
Journal of Zhejiang University. Science. B
March 1, 2015
Sałat K, Filipek B.
(16)
Menthol suppresses laryngeal C-fiber hypersensitivity to cigarette smoke in a rat model of gastroesophageal reflux disease: the role of TRPM8
Journal of applied physiology (Bethesda, Md. : 1985)
March 1, 2015
Liu BY, Lin YJ, Lee HF, Ho CY, Ruan T, Kou YR.
(17)
Differential Contribution of TRPA1, TRPV4 and TRPM8 to Colonic Nociception in Mice
PloS one
January 1, 2015
Mueller-Tribbensee SM, Karna M, Khalil M, Neurath MF, Reeh PW, Engel MA.
(18)
TRPA1 is essential for the vascular response to environmental cold exposure
Nature communications
December 11, 2014
Aubdool AA, Graepel R, Kodji X, Alawi KM, Bodkin JV, Srivastava S, Gentry C, Heads R, Grant AD, Fernandes ES,
et al
.
(19)
Investigating the potential role of TRPA1 in locomotion and cardiovascular control during hypertension
Pharmacology research & perspectives
August 1, 2014
Bodkin JV, Thakore P, Aubdool AA, Liang L, Fernandes ES, Nandi M, Spina D, Clark JE, Aaronson PI, Shattock MJ,
et al
.
(20)
TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins
Nature communications
January 1, 2014
Meseguer V, Alpizar YA, Luis E, Tajada S, Denlinger B, Fajardo O, Manenschijn JA, Fernández-Peña C, Talavera A, Kichko T,
et al
.
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Reviews
Be the First to Write a Review!
HC 030031 from Tocris Bioscience, a Bio-Techne Brand
Supplier Page
View Company Product Page
$201.00
Product Specs
Company Info
Citations
Reviews
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