FAK Inhibitor 14 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemFAK Inhibitor 14
CompanyTocris Bioscience, a Bio-Techne Brand
Price $170.00Supplier Page View Company Product Page
Catalog Number3414/10
Quantity10 mg (also 50 mg)
Molecular Weight284.01
Molecule Name1,2,4,5-Benzenetetramine tetrahydrochloride
FormulaC6H10N4.4HCl
StorageDesiccate at RT

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Focal adhesion kinase confers pro-migratory and antiapoptotic properties and is a potential therapeutic target in Ewing sarcomaMolecular oncologyFebruary 1, 2020Steinestel K, Trautmann M, Jansen EP, Dirksen U, Rehkämper J, Mikesch JH, Gerke JS, Orth MF, Sannino G, Arteaga MF, et al.

(2) Vitronectin from brain pericytes promotes adult forebrain neurogenesis by stimulating CNTFExperimental neurologyFebruary 1, 2019Jia C, Keasey MP, Malone HM, Lovins C, Sante RR, Razskazovskiy V, Hagg T.

(3) Plectin protects podocytes from adriamycin-induced apoptosis and F-actin cytoskeletal disruption through the integrin α6β4/FAK/p38 MAPK pathwayJournal of cellular and molecular medicineNovember 1, 2018Ni Y, Wang X, Yin X, Li Y, Liu X, Wang H, Liu X, Zhang J, Gao H, Shi B, et al.

(4) Matrix stiffness modulates infection of endothelial cells by Listeria monocytogenes via expression of cell surface vimentinMolecular biology of the cellJuly 1, 2018Bastounis EE, Yeh YT, Theriot JA.

(5) Fibroblast activation protein-α promotes the growth and migration of lung cancer cells via the PI3K and sonic hedgehog pathwaysInternational journal of molecular medicineJanuary 1, 2018Jia J, Martin TA, Ye L, Meng L, Xia N, Jiang WG, Zhang X.

(6) Netrin-1 Preserves Blood-Brain Barrier Integrity Through Deleted in Colorectal Cancer/Focal Adhesion Kinase/RhoA Signaling Pathway Following Subarachnoid Hemorrhage in RatsJournal of the American Heart AssociationMay 19, 2017Xie Z, Enkhjargal B, Reis C, Huang L, Wan W, Tang J, Cheng Y, Zhang JH.

(7) Homodimers of Vanillin and Apocynin Decrease the Metastatic Potential of Human Cancer Cells by Inhibiting the FAK/PI3K/Akt Signaling PathwayJournal of agricultural and food chemistryMarch 22, 2017Jantaree P, Lirdprapamongkol K, Kaewsri W, Thongsornkleeb C, Choowongkomon K, Atjanasuppat K, Ruchirawat S, Svasti J.

(8) Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3Cell communication and signaling : CCSDecember 15, 2016Visavadiya NP, Keasey MP, Razskazovskiy V, Banerjee K, Jia C, Lovins C, Wright GL, Hagg T.

(9) Endothelial Cells Use a Formin-Dependent Phagocytosis-Like Process to Internalize the Bacterium Listeria monocytogenesPLoS pathogensMay 1, 2016Rengarajan M, Hayer A, Theriot JA.

(10) Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancerOncotargetApril 26, 2016An XZ, Zhao ZG, Luo YX, Zhang R, Tang XQ, Hao D, Zhao X, Lv X, Liu D.

(11) Palladin mediates stiffness-induced fibroblast activation in the tumor microenvironmentBiophysical journalJuly 21, 2015McLane JS, Ligon LA.

(12) CD146 mediates VEGF-induced melanoma cell extravasation through FAK activationInternational journal of cancerJuly 1, 2015Jouve N, Bachelier R, Despoix N, Blin MG, Matinzadeh MK, Poitevin S, Aurrand-Lions M, Fallague K, Bardin N, Blot-Chabaud M, et al.

(13) Inhibition of STAT3, FAK and Src mediated signaling reduces cancer stem cell load, tumorigenic potential and metastasis in breast cancerScientific reportsMay 14, 2015Thakur R, Trivedi R, Rastogi N, Singh M, Mishra DP.

(14) RECK-Mediated β1-Integrin Regulation by TGF-β1 Is Critical for Wound Contraction in MicePloS oneJanuary 1, 2015Gutiérrez J, Droppelmann CA, Contreras O, Takahashi C, Brandan E.

(15) Combination of heat shock protein 90 and focal adhesion kinase inhibitors synergistically inhibits the growth of non-small cell lung cancer cellsOncoscienceJanuary 1, 2015Webber PJ, Park C, Qui M, Ramalingam SS, Khuri FR, Fu H, Du Y.

(16) The Src homology-2 protein Shb modulates focal adhesion kinase signaling in a BCR-ABL myeloproliferative disorder causing accelerated progression of diseaseJournal of hematology & oncologyJune 21, 2014Gustafsson K, Jamalpour M, Trinh C, Kharas MG, Welsh M.

(17) Astroglial-derived periostin promotes axonal regeneration after spinal cord injuryThe Journal of neuroscience : the official journal of the Society for NeuroscienceFebruary 12, 2014Shih CH, Lacagnina M, Leuer-Bisciotti K, Pröschel C.

(18) Transmembrane collagen XVII modulates integrin dependent keratinocyte migration via PI3K/Rac1 signalingPloS oneJanuary 1, 2014Löffek S, Hurskainen T, Jackow J, Sigloch FC, Schilling O, Tasanen K, Bruckner-Tuderman L, Franzke CW.

(19) ORAI1 calcium channel orchestrates skin homeostasisProceedings of the National Academy of Sciences of the United States of AmericaDecember 10, 2013Vandenberghe M, Raphaël M, Lehen'kyi V, Gordienko D, Hastie R, Oddos T, Rao A, Hogan PG, Skryma R, Prevarskaya N.

(20) CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin releaseThe Journal of biological chemistryNovember 8, 2013Malenczyk K, Jazurek M, Keimpema E, Silvestri C, Janikiewicz J, Mackie K, Di Marzo V, Redowicz MJ, Harkany T, Dobrzyn A.

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FAK Inhibitor 14

FAK Inhibitor 14 from Tocris Bioscience, a Bio-Techne Brand

Description

Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

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FAK Inhibitor 14 from Tocris Bioscience, a Bio-Techne Brand

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