PQ 401 from Tocris Bioscience, a Bio-Techne Brand | Biocompare.com

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PQ 401

IGF1R inhibitor

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Tocris Bioscience, a Bio-Techne Brand for
PQ 401

Description

IGF1R inhibitor

Product Specs
ItemPQ 401
CompanyTocris Bioscience, a Bio-Techne Brand
Price $216.00Supplier Page View Company Product Page
Catalog Number2768/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight341.79
Molecule NameN-(5-Chloro-2-methoxyphenyl)-N'-(2-methyl-4-quinolinyl)urea
FormulaC18H16ClN3O2
StorageStore at +4°C

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) The Neutrally Charged Diarylurea Compound PQ401 Kills Antibiotic-Resistant and Antibiotic-Tolerant Staphylococcus aureusmBioJune 30, 2020Kim W, Zou G, Pan W, Fricke N, Faizi HA, Kim SM, Khader R, Li S, Lee K, Escorba I, et al.

(2) Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruliAmerican journal of physiology. Cell physiologyNovember 15, 2013Ilatovskaya DV, Palygin O, Levchenko V, Staruschenko A.

(3) Insulin-like growth factor (IGF) binding protein 2 functions coordinately with receptor protein tyrosine phosphatase β and the IGF-I receptor to regulate IGF-I-stimulated signalingMolecular and cellular biologyOctober 1, 2012Shen X, Xi G, Maile LA, Wai C, Rosen CJ, Clemmons DR.

(4) Activation of the insulin-like growth factor-1 receptor induces resistance to epidermal growth factor receptor antagonism in head and neck squamous carcinoma cellsMolecular cancer therapeuticsNovember 1, 2011Jameson MJ, Beckler AD, Taniguchi LE, Allak A, Vanwagner LB, Lee NG, Thomsen WC, Hubbard MA, Thomas CY.

(5) Insulin-like growth factor 1-mediated hyperthermia involves anterior hypothalamic insulin receptorsThe Journal of biological chemistryApril 29, 2011Sanchez-Alavez M, Osborn O, Tabarean IV, Holmberg KH, Eberwine J, Kahn CR, Bartfai T.

(6) Insulin-like growth factor-I-stimulated insulin receptor substrate-1 negatively regulates Src homology 2 domain-containing protein-tyrosine phosphatase substrate-1 function in vascular smooth muscle cellsThe Journal of biological chemistryMay 21, 2010Radhakrishnan Y, Busby WH Jr, Shen X, Maile LA, Clemmons DR.

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