KN-62 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemKN-62
CompanyTocris Bioscience, a Bio-Techne Brand
Price $211.00Supplier Page View Company Product Page
Catalog Number1277/1
Quantity1 mg
Purity98%
Molecular Weight721.84
Molecule Name4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl] phenyl isoquinolinesulfonic acid ester
FormulaC38H35N5O6S2
StorageStore at -20°C

Sizes Available: 1 mg

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

(1) Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21Cell reportsSeptember 3, 2019Sahu BS, Rodriguez P, Nguyen ME, Han R, Cero C, Razzoli M, Piaggi P, Laskowski LJ, Pavlicev M, Muglia L, et al.

(2) Secreted Amyloid Precursor Protein-Alpha Promotes Arc Protein Synthesis in Hippocampal NeuronsFrontiers in molecular neuroscienceJanuary 1, 2019Livingstone RW, Elder MK, Barrett MC, Westlake CM, Peppercorn K, Tate WP, Abraham WC, Williams JM.

(5) Endocannabinoid dynamics gate spike-timing dependent depression and potentiationeLifeFebruary 27, 2016Cui Y, Prokin I, Xu H, Delord B, Genet S, Venance L, Berry H.

(6) Neurophysiological mechanisms of bradykinin-evoked mucosal chloride secretion in guinea pig small intestineWorld journal of gastrointestinal pathophysiologyFebruary 15, 2016Qu MH, Ji WS, Zhao TK, Fang CY, Mao SM, Gao ZQ.

(7) Mitochondrial Dysfunction, Depleted Purinergic Signaling, and Defective T Cell Vigilance and Immune DefenseThe Journal of infectious diseasesFebruary 1, 2016Ledderose C, Bao Y, Ledderose S, Woehrle T, Heinisch M, Yip L, Zhang J, Robson SC, Shapiro NI, Junger WG.

(10) Modulation of P2X4/P2X7/Pannexin-1 sensitivity to extracellular ATP via Ivermectin induces a non-apoptotic and inflammatory form of cancer cell deathScientific reportsNovember 10, 2015Draganov D, Gopalakrishna-Pillai S, Chen YR, Zuckerman N, Moeller S, Wang C, Ann D, Lee PP.(Sigma I8898-250MG), KN-93 (Tocris, 5215-1 MG), Cyclosporin A (Tocris, 1101–100 MG), KN-62 (Tocris, 1277-1 MG), PSB 069 (Santa Cruz, sc-204216 10 MG), DCPIB (Tocris, 1540–10 MG), A438079 (Tocris, 2972–10 MG),

(11) Human β Defensin-3 Increases CD86 Expression on Monocytes by Activating the ATP-Gated Channel P2X7Journal of immunology (Baltimore, Md. : 1950)November 1, 2015Lioi AB, Ferrari BM, Dubyak GR, Weinberg A, Sieg SF.

(12) Synapse-specific compartmentalization of signaling cascades for LTP induction in CA3 interneuronsNeuroscienceApril 2, 2015Galván EJ, Pérez-Rosello T, Gómez-Lira G, Lara E, Gutiérrez R, Barrionuevo G.

(17) Nucleotide receptors control IL-8/CXCL8 and MCP-1/CCL2 secretions as well as proliferation in human glioma cellsBiochimica et biophysica actaJanuary 1, 2015Braganhol E, Kukulski F, Lévesque SA, Fausther M, Lavoie EG, Zanotto-Filho A, Bergamin LS, Pelletier J, Bahrami F, Ben Yebdri F, et al.

(18) Ca(2+) -related signaling events influence TLR9-induced IL-10 secretion in human B cellsEuropean journal of immunologyMay 1, 2014Ziegler S, Gartner K, Scheuermann U, Zoeller T, Hantzschmann J, Over B, Foermer S, Heeg K, Bekeredjian-Ding I.