Picrotoxin from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemPicrotoxin
CompanyTocris Bioscience, a Bio-Techne Brand
Price $88.00Supplier Page View Company Product Page
Catalog Number1128/1G
Quantity1 g
Molecular Weight602.59
FormulaC30H34O13
Purity97%
StorageStore at RT

Specifications/Features

Sizes Available: 1 g

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Transcription-replication conflicts underlie sensitivity to PARP inhibitorsNatureApril 1, 2024Petropoulos M, Karamichali A, Rossetti GG, Freudenmann A, Iacovino LG, Dionellis VS, Sotiriou SK, Halazonetis TD.

(2) A novel isolation method for spontaneously released extracellular vesicles from brain tissue and its implications for stress-driven brain pathologyCell communication and signaling : CCSFebruary 13, 2023Gomes PA, Bodo C, Nogueras-Ortiz C, Samiotaki M, Chen M, Soares-Cunha C, Silva JM, Coimbra B, Stamatakis G, Santos L, et al.0.2 mg ml−1and added to the EV-release medium to a final concentration of 20 µM. Picrotoxin (cat. No. 1128/1G, Tocris) was dissolved in tissue culture–grade DMSO at 100 mM. Picrotoxin solution was added to the

(3) Cell-type-specific integration of feedforward and feedback synaptic inputs in the posterior parietal cortexNeuronNovember 1, 2022Daniel J. Rindner, Archana Proddutur, Gyorgy Lur#1069/1 Mibefradil dihydrochloride,Tocris,Cat. #2198/10 D-AP5,Tocris,Cat. #0106/1 Picrotoxin,Tocris,Cat. #1128/1G NBQX disodium salt,Tocris,Cat. #1044/1 QX 314 Bromide,HelloBio,Cat. #HB1029 4-Aminopyridine (4-AP),Tocris,Cat.

(4) Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit–Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in MiceBiological PsychiatryAugust 1, 2022Timothy A. Troppoli, Panos Zanos, Polymnia Georgiou, Todd D. Gould, Uwe Rudolph, Scott M. ThompsonDrug,flumazenil,Tocris Bioscience,Cat. No. 1328, Chemical Compound or Drug,picrotoxin,Tocris Bioscience,Cat. No. 1128/1G, Chemical Compound or Drug,CGP54626,Tocris Bioscience,Cat. No. 1088/10, Chemical Compound or Drug,DNQX,Sigma-Aldrich,Cat.

(5) Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagyeLifeJanuary 8, 2020Lieberman OJ, Frier MD, McGuirt AF, Griffey CJ, Rafikian E, Yang M, Yamamoto A, Borgkvist A, Santini E, Sulzer D.,Tetrodotoxin citrate,Tocris Biosciences,Cat # 1069/1, "Chemical compound, drug",Picrotoxin,Tocris Biosciences,Cat # 1128/1G, "Chemical compound, drug",SNAP-Cell 505-Star,New England Biolabs,Cat # S9103S, "Chemical compound,

(6) Linking NMDA Receptor Synaptic Retention to Synaptic Plasticity and CognitioniScienceSeptember 27, 2019Franchini L, Stanic J, Ponzoni L, Mellone M, Carrano N, Musardo S, Zianni E, Olivero G, Marcello E, Pittaluga A, et al.

(7) TMEM16B regulates anxiety-related behavior and GABAergic neuronal signaling in the central lateral amygdalaeLifeSeptember 4, 2019Li KX, He M, Ye W, Simms J, Gill M, Xiang X, Jan YN, Jan LY.https://biorender.com/. Reagents Pharmacological drugs used included 100 mM Picrotoxin (Tocris, Cat. No. 1128/1G), 50 mM DL-AP5 (Tocris, Cat. No. 0105/10), 20 mM DNQX (Tocris, Cat. No. 2312/10), Tetrodotoxin (abcam, ab120054),

(8) Prenatal selective serotonin reuptake inhibitor (SSRI) exposure induces working memory and social recognition deficits by disrupting inhibitory synaptic networks in male miceMolecular brainApril 1, 2019Yu W, Yen YC, Lee YH, Tan S, Xiao Y, Lokman H, Ting AKT, Ganegala H, Kwon T, Ho WK, et al.

(9) KCC2-Mediated Cl^- Extrusion Modulates Spontaneous Hippocampal Network Events in Perinatal Rats and MiceCell reportsJanuary 29, 2019Spoljaric I, Spoljaric A, Mavrovic M, Seja P, Puskarjov M, Kaila K.

(10) Augmented Reticular Thalamic Bursting and Seizures in Scn1a-Dravet SyndromeCell ReportsJanuary 2, 2019Stefanie Ritter-Makinson et al.-Ethyl-2-benzimidazolinone),Tocris,Cat. # 1041 Apamin,Sigma,Cat. # A1289 Kynurenic Acid,Sigma,Cat. # K3375 Picrotoxin,Tocris,Cat. #1128/1G Experimental Models: Organisms/Strains,, Mouse: Scn1aR1407+/− C57BL6J:C3HeB/FeJ,"(Ogiwara et al.,

(11) Altered Behaviors and Impaired Synaptic Function in a Novel Rat Model With a Complete Shank3 DeletionFrontiers in cellular neuroscienceJanuary 1, 2019Song TJ, Lan XY, Wei MP, Zhai FJ, Boeckers TM, Wang JN, Yuan S, Jin MY, Xie YF, Dang WW, et al.

(12) Toxoplasma-Induced Hypermigration of Primary Cortical Microglia Implicates GABAergic SignalingFrontiers in cellular and infection microbiologyJanuary 1, 2019Bhandage AK, Kanatani S, Barragan A.

(13) The Probability of Neurotransmitter Release Governs AMPA Receptor Trafficking via Activity-Dependent Regulation of mGluR1 Surface ExpressionCell ReportsDecember 26, 2018Thomas M. Sanderson et al.0114/50 4-Aminopyridine,Tocris,Cat# 0940/100 TBOA,Tocris,Cat# 1223/10 or HB0258 Picrotoxin,Tocris/HelloBio,Cat# 1128/1G or HB0506 FM4-64,Life Technologies,Cat# T13320 ADVASEP-7,Biotium,Cat# 70029 2-chloroadenosine,Santa Cruz Biotechnology

(14) Dopamine Cells Differentially Regulate Striatal Cholinergic Transmission across Regions through Corelease of Dopamine and GlutamateCell reportsDecember 11, 2018Cai Y, Ford CP.

(15) Foxp2 loss of function increases striatal direct pathway inhibition via increased GABA releaseBrain structure & functionDecember 1, 2018van Rhijn JR, Fisher SE, Vernes SC, Nadif Kasri N.

(16) AKAP150 Palmitoylation Regulates Synaptic Incorporation of Ca²⁺-Permeable AMPA Receptors to Control LTPCell reportsOctober 23, 2018Purkey AM, Woolfrey KM, Crosby KC, Stich DG, Chick WS, Aoto J, Dell'Acqua ML.

(17) The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal SequencesCell reportsOctober 23, 2018McKay S, Ryan TJ, McQueen J, Indersmitten T, Marwick KFM, Hasel P, Kopanitsa MV, Baxter PS, Martel MA, Kind PC, et al.1069/1 (+)-MK801 maleate,Tocris,Cat# 0924/10 (+)-Bicuculline,Tocris,Cat# 0130/50 Picrotoxin,Tocris,Cat# 1128/1G Spermine,Sigma,Cat# S3256-1G Ifenprodil hemitartrate,Tocris,Cat# 0545/10 ,, Experimental Models:

(18) All-optical synaptic electrophysiology probes mechanism of ketamine-induced disinhibitionNature methodsOctober 1, 2018Fan LZ, Nehme R, Adam Y, Jung ES, Wu H, Eggan K, Arnold DB, Cohen AE.

(19) Feature Article: Selective modulation of tonically active GABA_A receptor functional subgroups by G-proteins and protein kinase CExperimental biology and medicine (Maywood, N.J.)September 1, 2018O'Neill N, Sylantyev S.

(20) Functional Distinctions between Spine and Dendritic Synapses Made onto Parvalbumin-Positive Interneurons in Mouse CortexCell reportsAugust 21, 2018Sancho L, Bloodgood BL.

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Picrotoxin

Picrotoxin from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

Citations (143)

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Picrotoxin from Tocris Bioscience, a Bio-Techne Brand

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