SANT-1 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemSANT-1
CompanyTocris Bioscience, a Bio-Techne Brand
Price $257.00Supplier Page View Company Product Page
Catalog Number1974/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight373.5
Molecule NameN-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamine
FormulaC23H27N5
StorageStore at +4°C

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Human NKX2.2 influences islet endocrine cell fate choices through regulation of WNT pathway genesbioRxivJanuary 16, 2026Christopher Schaaf, Fiona M. Docherty, Madison X. Rodriguez, Patrick Sean McGrath, Christopher J. Hill, Kristen L. Wells, Lori SusselA4544)Stage 3 (days 7-8): 2 μM retinoic acid (Selleckchem, S1653), 50 ng/mL KGF, 0.25 μM SANT1 (Tocris, 1974/10), 0.2 μM LDN (Tocris, 6053/50), 0.2 μM TPPB (Tocris, 0761/50), 2.5 μM L-ascorbic acid, 0.5% ITS-X (Gibco,

(2) Stem-Cell-Derived β-Like Cells with a Functional PTPN2 Knockout Display Increased ImmunogenicityCellsNovember 30, 2022Triolo TM, Matuschek JQ, Castro-Gutierrez R, Shilleh AH, Williams SPM, Hansen MS, McDaniel K, Barra JM, Michels A, Russ HA.

(3) Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signalsNature communicationsOctober 11, 2019Yung T, Poon F, Liang M, Coquenlorge S, McGaugh EC, Hui CC, Wilson MD, Nostro MC, Kim TH.

(4) Generation of hepatocyte- and endocrine pancreatic-like cells from human induced endodermal progenitor cellsPloS oneJanuary 1, 2018Sambathkumar R, Akkerman R, Dastidar S, Roelandt P, Kumar M, Bajaj M, Mestre Rosa AR, Helsen N, Vanslembrouck V, Kalo E, et al.

(5) Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitorsNature communicationsAugust 24, 2017Cogger KF, Sinha A, Sarangi F, McGaugh EC, Saunders D, Dorrell C, Mejia-Guerrero S, Aghazadeh Y, Rourke JL, Screaton RA, et al.

(6) Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic ProgenitorsDevelopmental cellApril 24, 2017Krentz NAJ, van Hoof D, Li Z, Watanabe A, Tang M, Nian C, German MS, Lynn FC.

(7) Hedgehog associated to microparticles inhibits adipocyte differentiation via a non-canonical pathwayScientific reportsMarch 24, 2016Fleury A, Hoch L, Martinez MC, Faure H, Taddei M, Petricci E, Manetti F, Girard N, Mann A, Jacques C, et al.

(8) Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiationNature communicationsMarch 21, 2016Yuan X, Cao J, He X, Serra R, Qu J, Cao X, Yang S.

(9) MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptorFASEB journal : official publication of the Federation of American Societies for Experimental BiologyMay 1, 2015Hoch L, Faure H, Roudaut H, Schoenfelder A, Mann A, Girard N, Bihannic L, Ayrault O, Petricci E, Taddei M, et al.

(10) Efficient generation of NKX6-1+ pancreatic progenitors from multiple human pluripotent stem cell linesStem cell reportsApril 14, 2015Nostro MC, Sarangi F, Yang C, Holland A, Elefanty AG, Stanley EG, Greiner DL, Keller G.

(11) Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding proteinCell reportsFebruary 3, 2015Strating JR, van der Linden L, Albulescu L, Bigay J, Arita M, Delang L, Leyssen P, van der Schaar HM, Lanke KH, Thibaut HJ, et al.

(12) GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomasNatureFebruary 28, 2013Atwood SX, Li M, Lee A, Tang JY, Oro AE.

(13) Glucocorticoid compounds modify smoothened localization and hedgehog pathway activityChemistry & biologyAugust 24, 2012Wang Y, Davidow L, Arvanites AC, Blanchard J, Lam K, Xu K, Oza V, Yoo JW, Ng JM, Curran T, et al.

(14) Lmx1a allows context-specific isolation of progenitors of GABAergic or dopaminergic neurons during neural differentiation of embryonic stem cellsStem CellsJuly 1, 2012Nefzger CM, Su CT, Fabb SA, Hartley BJ, Beh SJ, Zeng WR, Haynes JM, Pouton CW.

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SANT-1

SANT-1 from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

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SANT-1 from Tocris Bioscience, a Bio-Techne Brand

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