Rapamycin from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemRapamycin
CompanyTocris Bioscience, a Bio-Techne Brand
Price $406.00Supplier Page View Company Product Page
Catalog Number1292/1
Quantity1 mg
Purity98%
Molecular Weight914.18
Molecule Name(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-ep
FormulaC51H79NO13
StorageStore at -20°C

Specifications/Features

Sizes Available: 1 mg

Add to Compare List

Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Exosomes from EGFR-Mutated Adenocarcinoma Induce a Hybrid EMT and MMP9-Dependant Tumor InvasionCancersAugust 3, 2022Jouida A, O'Callaghan M, Mc Carthy C, Fabre A, Nadarajan P, Keane MP.½ (Tocris Bioscience, Bristol, UK, Cat#: 5773/10), rapamycin (Tocris Bioscience, Bristol, UK, Cat#: 1292/1) and a specific MMP-9 inhibitor (Abcam, Cambridge, UK, Cat#: ab142180). The cell monolayers were scratched

(2) MBNL1 reverses the proliferation defect of skeletal muscle satellite cells in myotonic dystrophy type 1 by inhibiting autophagy via the mTOR pathwayCell death & diseaseJuly 18, 2020Song KY, Guo XM, Wang HQ, Zhang L, Huang SY, Huo YC, Zhang G, Feng JZ, Zhang RR, Ma Y, et al.overexpression, DM1-03 and DM1-13-3 were serum-starved for 24 h before being treated with 50 nM rapamycin (no. 1292/1, Tocris, Bristol, UK), as recommended in previous publications77. To overexpress mTOR, DM1-03 and DM1-13-3

(3) Direct Gα_q Gating Is the Sole Mechanism for TRPM8 Inhibition Caused by Bradykinin Receptor ActivationCell reportsJune 18, 2019Zhang X.

(4) Melatonin: The smart molecule that differentially modulates autophagy in tumor and normal placental cellsPloS oneJanuary 1, 2019Sagrillo-Fagundes L, Bienvenue-Pariseault J, Vaillancourt C.

(5) Secreted Amyloid Precursor Protein-Alpha Promotes Arc Protein Synthesis in Hippocampal NeuronsFrontiers in molecular neuroscienceJanuary 1, 2019Livingstone RW, Elder MK, Barrett MC, Westlake CM, Peppercorn K, Tate WP, Abraham WC, Williams JM.

(6) Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage MetabolismCell metabolismMay 1, 2018Lancaster GI, Langley KG, Berglund NA, Kammoun HL, Reibe S, Estevez E, Weir J, Mellett NA, Pernes G, Conway JRW, et al.

(7) Upregulation of IRS1 Enhances IGF1 Response in Y537S and D538G ESR1 Mutant Breast Cancer CellsEndocrinologyJanuary 1, 2018Li Z, Levine KM, Bahreini A, Wang P, Chu D, Park BH, Oesterreich S, Lee AV.

(8) Ras-Induced miR-146a and 193a Target Jmjd6 to Regulate Melanoma ProgressionFrontiers in geneticsJanuary 1, 2018Anelli V, Ordas A, Kneitz S, Sagredo LM, Gourain V, Schartl M, Meijer AH, Mione M.

(9) Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1Stem cell reportsAugust 8, 2017Tripathi P, Rodriguez-Muela N, Klim JR, de Boer AS, Agrawal S, Sandoe J, Lopes CS, Ogliari KS, Williams LA, Shear M, et al.

(10) Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1α and VEGF receptorsPloS oneJanuary 1, 2017Mahfouz N, Tahtouh R, Alaaeddine N, El Hajj J, Sarkis R, Hachem R, Raad I, Hilal G.

(11) Senescent stromal cell-induced divergence and therapeutic resistance in T cell acute lymphoblastic leukemia/lymphomaOncotargetDecember 13, 2016Habiel DM, Krepostman N, Lilly M, Cavassani K, Coelho AL, Shibata T, Elenitoba-Johnson K, Hogaboam CM.

(12) Vitamin C alleviates aging defects in a stem cell model for Werner syndromeProtein & cellJuly 1, 2016Li Y, Zhang W, Chang L, Han Y, Sun L, Gong X, Tang H, Liu Z, Deng H, Ye Y, et al.

(13) Eicosapentaenoic acid attenuates dexamethasome-induced apoptosis by inducing adaptive autophagy via GPR120 in murine bone marrow-derived mesenchymal stem cellsCell death & diseaseMay 26, 2016Gao B, Han YH, Wang L, Lin YJ, Sun Z, Lu WG, Hu YQ, Li JQ, Lin XS, Liu BH, et al.

(14) Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomasOncotargetApril 12, 2016Jennewein L, Ronellenfitsch MW, Antonietti P, Ilina EI, Jung J, Stadel D, Flohr LM, Zinke J, von Renesse J, Drott U, et al.

(15) Mechanistic Target of Rapamycin Complex 1/S6 Kinase 1 Signals Influence T Cell Activation Independently of Ribosomal Protein S6 PhosphorylationJournal of immunology (Baltimore, Md. : 1950)November 15, 2015Salmond RJ, Brownlie RJ, Meyuhas O, Zamoyska R.

(16) PAK2 is an effector of TSC1/2 signaling independent of mTOR and a potential therapeutic target for Tuberous Sclerosis ComplexScientific reportsSeptember 28, 2015Alves MM, Fuhler GM, Queiroz KC, Scholma J, Goorden S, Anink J, Spek CA, Hoogeveen-Westerveld M, Bruno MJ, Nellist M, et al.

(17) Inflammation-induced desmoglein-2 ectodomain shedding compromises the mucosal barrierMolecular biology of the cellSeptember 15, 2015Kamekura R, Nava P, Feng M, Quiros M, Nishio H, Weber DA, Parkos CA, Nusrat A.

(18) GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signallingThe Biochemical journalSeptember 1, 2015Stretton C, Hoffmann TM, Munson MJ, Prescott A, Taylor PM, Ganley IG, Hundal HS.

(19) Cardiolipin remodeling by TAZ/tafazzin is selectively required for the initiation of mitophagyAutophagyApril 3, 2015Hsu P, Liu X, Zhang J, Wang HG, Ye JM, Shi Y.

(20) Phosphatidylethanolamine positively regulates autophagy and longevityCell death and differentiationMarch 1, 2015Rockenfeller P, Koska M, Pietrocola F, Minois N, Knittelfelder O, Sica V, Franz J, Carmona-Gutierrez D, Kroemer G, Madeo F.

Be the First to Write a Review!

Rapamycin

Rapamycin from Tocris Bioscience, a Bio-Techne Brand

Description

Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

Citations (56)

Reviews

Rapamycin from Tocris Bioscience, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map