L-685,458 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemL-685,458
CompanyTocris Bioscience, a Bio-Techne Brand
Price $406.00Supplier Page View Company Product Page
Catalog Number2627/1
Quantity1 mg
Purity97%
Molecular Weight672.85
Molecule Name(5S)-(tert-Butoxycarbonylamino)-6-phenyl-(4R)-hydroxy-(2R)-benzylhexanoyl)-L-leucy-L-phenylalaninamide
FormulaC39H52N4O6
StorageStore at -20°C

Sizes Available: 1 mg

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

(1) Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysisNature communicationsApril 6, 2022Mentrup T, Stumpff-Niggemann AY, Leinung N, Schlosser C, Schubert K, Wehner R, Tunger A, Schatz V, Neubert P, Gradtke AC, et al.

(2) Spatial patterning of liver progenitor cell differentiation mediated by cellular contractility and Notch signalingeLifeDecember 27, 2018Kaylan KB, Berg IC, Biehl MJ, Brougham-Cook A, Jain I, Jamil SM, Sargeant LH, Cornell NJ, Raetzman LT, Underhill GH.

(3) APP upregulation contributes to retinal ganglion cell degeneration via JNK3Cell death and differentiationMarch 1, 2018Liu C, Zhang CW, Zhou Y, Wong WQ, Lee LC, Ong WY, Yoon SO, Hong W, Fu XY, Soong TW, et al.

(4) HIV-1 counteracts an innate restriction by amyloid precursor protein resulting in neurodegenerationNature communicationsNovember 15, 2017Chai Q, Jovasevic V, Malikov V, Sabo Y, Morham S, Walsh D, Naghavi MH.

(5) ODZ1 allows glioblastoma to sustain invasiveness through a Myc-dependent transcriptional upregulation of RhoAOncogeneMarch 23, 2017Talamillo A, Grande L, Ruiz-Ontañon P, Velasquez C, Mollinedo P, Torices S, Sanchez-Gomez P, Aznar A, Esparis-Ogando A, Lopez-Lopez C, et al.

(7) Differential Inhibition of Signal Peptide Peptidase Family Members by Established γ-Secretase InhibitorsPloS oneJanuary 1, 2015Ran Y, Ladd GZ, Ceballos-Diaz C, Jung JI, Greenbaum D, Felsenstein KM, Golde TE.

(8) Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypesNature biotechnologyJanuary 1, 2015Maury Y, Côme J, Piskorowski RA, Salah-Mohellibi N, Chevaleyre V, Peschanski M, Martinat C, Nedelec S.

(9) Canonical Notch signalling is inactive in urothelial carcinomaBMC cancerAugust 29, 2014Greife A, Jankowiak S, Steinbring J, Nikpour P, Niegisch G, Hoffmann MJ, Schulz WA.

(10) RAGE inhibition in microglia prevents ischemia-dependent synaptic dysfunction in an amyloid-enriched environmentThe Journal of neuroscience : the official journal of the Society for NeuroscienceJune 25, 2014Origlia N, Criscuolo C, Arancio O, Yan SS, Domenici L.

(11) γ-Secretase processing and effects of γ-secretase inhibitors and modulators on long Aβ peptides in cellsThe Journal of biological chemistryFebruary 7, 2014Ran Y, Cruz PE, Ladd TB, Fauq AH, Jung JI, Matthews J, Felsenstein KM, Golde TE.

(12) Blood stem cell fate regulation by Delta-1-mediated rewiring of IL-6 paracrine signalingBloodJanuary 30, 2014Csaszar E, Wang W, Usenko T, Qiao W, Delaney C, Bernstein ID, Zandstra PW.

(14) Regulation of CXCR4 by the Notch ligand delta-like 4 in endothelial cellsCancer researchMarch 15, 2008Williams CK, Segarra M, Sierra Mde L, Sainson RC, Tosato G, Harris AL.

L-685,458