(R)-CPP from Tocris Bioscience, a Bio-Techne Brand

Product Specs
Item(R)-CPP
CompanyTocris Bioscience, a Bio-Techne Brand
Price $505.00Supplier Page View Company Product Page
Catalog Number0247/10
Quantity10 mg (also 50 mg)
Molecular Weight252.21
Molecule Name3-((R)-2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid
FormulaC8H17N2O5P
StorageDesiccate at RT

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Cerebellar contributions to tau-mediated cognitive and behavioral dysfunctionCell ReportsAugust 26, 2025Lidiette Angeles-Perez, Chongyu Ren, Juliana Neniel, James Widner, Kunihiko Yamashiro, Yogesh Tak, Sushobhna Batra, Tommy Tan, Brian Nguyen, Marc Diamond, et al.proteins" ,, Clozapine-N-oxide dihydrochloride,Hello Bio,6149 NBQX,Sigma,N183 R-CPP,Tocris Bioscience,0247/10 Picrotoxin,Tocris Bioscience,1128 TTX,Tocris Bioscience,1069 Neurobiotin tracer,Vector Laboratories,SP-1120 Lipofectamine

(2) An antidepressant mechanism underlying the allosteric inhibition of GluN2D-incorporated NMDA receptors at GABAergic interneuronsSci AdvMarch 7, 2025Jilin Zhang, Jinjin Duan, Wei Li, Xian Wang, Shimin Ren, Luyu Ye, Fang Liu, Xiaoting Tian, Yang Xie, Yiming Huang, et al.concentrated to approximately 2 mg/ml for cryo-EM sample preparation. Glycine (1 mM), 600 μM R-CPP (Tocris, 0247-10), and 600 μM YY-23 were added into the protein sample and equilibrated by rotating for 30 min in 4°C.

(3) Functional sensory circuits built from neurons of two speciesCellApril 25, 2024Throesch BT, Bin Imtiaz MK, Muñoz-Castañeda R, Sakurai M, Hartzell AL, James KN, Rodriguez AR, Martin G, Lippi G, Kupriyanov S, et al.

(4) Cerebellar contribution to autism-relevant behaviors in fragile X syndrome modelsCell ReportsDecember 26, 2023Jennifer M. Gibson, Anthony Hernandez Vazquez, Kunihiko Yamashiro, Vikram Jakkamsetti, Chongyu Ren, Katherine Lei, Brianne Dentel, Juan M. Pascual, Peter T. Tsairecombinant proteins","Chemicals, peptides, and recombinant proteins" ,, TTX,Abcam,AB120054 R-CPP,Tocris,0247/10 NBQX,Sigma,N183 Picrotoxin,Tocris,1128 ,, Experimental models: Organisms/strains,Experimental models:

(5) Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2eLifeJuly 26, 2022Kosillo P, Ahmed KM, Aisenberg EE, Karalis V, Roberts BM, Cragg SJ, Bateup HS.,GYKI 52466 dihydrochloride,Tocris,"Cat #: 1,454",(10 μM) final "Chemical compound, drug",(R)-CPP,Tocris,Cat #: 0247,(10 μM) final "Chemical compound, drug",Picrotoxin,Tocris,"Cat #: 1,128",(50 μM) final "Software, algorithm",IMARIS,Oxford Instruments

(6) Increased glycine contributes to synaptic dysfunction and early mortality in Nprl2 seizure modeliScienceMay 20, 2022Dentel B, Angeles-Perez L, Ren C, Jakkamsetti V, Holley AJ, Caballero D, Oh E, Gibson J, Pascual JM, Huber KM, et al.Proteins" ,, Rapamycin,LC-Labs,R-5000 Probenecid,Sigma,P8761 NBQX,Sigma,N183 Picrotoxin,Tocris,1128 Strychnine,Sigma,S0532 Neurobiotin tracer,Vector Laboratories,SP-1120 TTX,Abcam,AB120054 R-CPP,Tocris,0247/10 7-Cl-KYNA,Tocris,0237 ,, Critical Commercial Assays,Critical Commercial Assays,Critical Commercial

(7) Soma-Targeted Imaging of Neural Circuits by Ribosome TetheringNeuronAugust 1, 2020Yiming Chen et al.repress neurotransmission and thus network activity: 10 μM CNQX (Tocris, 0190), 10 μM (R)-CPP (Tocris, 0247), 10 μM Gabazine (Tocris, 1262) and 1000 μM (S)-MCPG (Tocris, 0337) (Wardill et al., 2013). Fluorescence

(8) Molecular and anatomical organization of the dorsal raphe nucleuseLifeAugust 14, 2019Kee Wui Huang, Nicole E Ochandarena, Adrienne C Philson, Minsuk Hyun, Jaclyn E Birnbaum, Marcelo Cicconet, Bernardo L Sabatini,ThermoFisher Scientific,"Cat# A-21244, RRID:AB_2535812",1:500 "Chemical compound, drug",(R)-CPP,Tocris Bioscience,Cat# 0247,10 µM "Chemical compound, drug",Tetrodotoxin,Tocris Bioscience,Cat# 1069,1 µM "Chemical compound, drug",Kynurenic acid

(9) All-optical synaptic electrophysiology probes mechanism of ketamine-induced disinhibitionNature methodsOctober 1, 2018Fan LZ, Nehme R, Adam Y, Jung ES, Wu H, Eggan K, Arnold DB, Cohen AE.

(10) Heparan Sulfate Organizes Neuronal Synapses through Neurexin PartnershipsCellSeptember 6, 2018Zhang P, Lu H, Peixoto RT, Pines MK, Ge Y, Oku S, Siddiqui TJ, Xie Y, Wu W, Archer-Hartmann S, et al.

(11) The THO Complex Coordinates Transcripts for Synapse Development and Dopamine Neuron SurvivalCellSeptember 6, 2018Maeder CI, Kim JI, Liang X, Kaganovsky K, Shen A, Li Q, Li Z, Wang S, Xu XZS, Li JB, et al.

(12) Functional Distinctions between Spine and Dendritic Synapses Made onto Parvalbumin-Positive Interneurons in Mouse CortexCell reportsAugust 21, 2018Sancho L, Bloodgood BL.

(13) Potassium channels contribute to activity-dependent regulation of dendritic inhibitionPhysiological reportsJune 1, 2018Chang JT, Higley MJ.

(14) Reciprocal Circuits Linking the Prefrontal Cortex with Dorsal and Ventral Thalamic NucleiNeuronApril 18, 2018Collins DP, Anastasiades PG, Marlin JJ, Carter AG.

(15) A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque RetinaMolecular therapy : the journal of the American Society of Gene TherapyNovember 1, 2017Chaffiol A, Caplette R, Jaillard C, Brazhnikova E, Desrosiers M, Dubus E, Duhamel L, Macé E, Marre O, Benoit P, et al.

(16) Neuronal firing patterns outweigh circuitry oscillations in parkinsonian motor controlThe Journal of clinical investigationDecember 1, 2016Pan MK, Kuo SH, Tai CH, Liou JY, Pei JC, Chang CY, Wang YM, Liu WC, Wang TR, Lai WS, et al.

(17) Milnacipran remediates impulsive deficits in rats with lesions of the ventromedial prefrontal cortexThe international journal of neuropsychopharmacologyDecember 8, 2014Tsutsui-Kimura I, Yoshida T, Ohmura Y, Izumi T, Yoshioka M.

(18) Plasticity of binocularity and visual acuity are differentially limited by nogo receptorThe Journal of neuroscience : the official journal of the Society for NeuroscienceAugust 27, 2014Stephany CÉ, Chan LL, Parivash SN, Dorton HM, Piechowicz M, Qiu S, McGee AW.

(19) Cholinergic interneurons mediate fast VGluT3-dependent glutamatergic transmission in the striatumPloS oneApril 22, 2011Higley MJ, Gittis AH, Oldenburg IA, Balthasar N, Seal RP, Edwards RH, Lowell BB, Kreitzer AC, Sabatini BL.

(20) Synaptic circuit abnormalities of motor-frontal layer 2/3 pyramidal neurons in an RNA interference model of methyl-CpG-binding protein 2 deficiencyThe Journal of neuroscience : the official journal of the Society for NeuroscienceOctober 7, 2009Wood L, Gray NW, Zhou Z, Greenberg ME, Shepherd GM.

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(R)-CPP

(R)-CPP

(R)-CPP from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

Citations (22)

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(R)-CPP from Tocris Bioscience, a Bio-Techne Brand

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