HC 067047 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemHC 067047
CompanyTocris Bioscience, a Bio-Techne Brand
Price $301.00Supplier Page View Company Product Page
Catalog Number4100/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight471.51
Molecule Name2-Methyl-1-[3-(4-morpholinyl)propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide
FormulaC26H28F3N3O2
StorageStore at +4°C

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Assessing the Potency of the Novel Tocolytics 2-APB, Glycyl-H-1152, and HC-067047 in Pregnant Human MyometriumReproductive sciences (Thousand Oaks, Calif.)January 1, 2023Hossain MR, Tolosa JM, Young RC, Smith R, Paul JW.

(2) Endothelial cells promote smooth muscle cell resilience to H(2) O(2) -induced cell death in mouse cerebral arteriesActa physiologica (Oxford, England)June 1, 2022Norton CE, Shaw RL, Mittler R, Segal SS.

(3) Piezo1-mediated stellate cell activation causes pressure-induced pancreatic fibrosis in miceJCI insightApril 22, 2022Swain SM, Romac JM, Vigna SR, Liddle RA.

(4) Astrocytes regulate ultra-slow arteriole oscillations via stretch-mediated TRPV4-COX-1 feedbackCell reportsAugust 3, 2021Haidey JN, Peringod G, Institoris A, Gorzo KA, Nicola W, Vandal M, Ito K, Liu S, Fielding C, Visser F, et al.

(5) The Role of Transient Receptor Potential A1 and G Protein-Coupled Receptor 39 in Zinc-Mediated Acute and Chronic Itch in MiceFrontiers in molecular neuroscienceJanuary 1, 2021Hu Y, Fu QY, Fu DN, Wang XL, Wang ZH, Zhang JT, Xu WJ, Zhou GK, Chen LH, Liu T.

(6) Formalin Itch Test: Low-Dose Formalin Induces Histamine-Independent, TRPA1-Mediated Itch in MiceFrontiers in medicineJanuary 1, 2021Liu X, Zhang JT, Hu Y, Shan WQ, Wang ZH, Fu QY, Fu DN, Ji J, Liu T.

(7) Piezo1 acts upstream of TRPV4 to induce pathological changes in endothelial cells due to shear stressThe Journal of biological chemistryJanuary 1, 2021Swain SM, Liddle RA.

(8) VEGF-B Is an Autocrine Gliotrophic Factor for Müller Cells under Pathologic ConditionsInvestigative ophthalmology & visual scienceSeptember 1, 2020Llorián-Salvador M, Barabas P, Byrne EM, Lechner J, Augustine J, Curtis TM, Chen M, Xu H.

(9) TRPV4 channel opening mediates pressure-induced pancreatitis initiated by Piezo1 activationThe Journal of clinical investigationMay 1, 2020Swain SM, Romac JM, Shahid RA, Pandol SJ, Liedtke W, Vigna SR, Liddle RA.

(10) Female sex and Western-style diet protect mouse resistance arteries during acute oxidative stressAmerican journal of physiology. Cell physiologyMarch 1, 2020Norton CE, Jacobsen NL, Sinkler SY, Manrique-Acevedo C, Segal SS.

(11) Cell sensing and decision-making in confinement: The role of TRPM7 in a tug of war between hydraulic pressure and cross-sectional areaScience advancesJuly 1, 2019Zhao R, Afthinos A, Zhu T, Mistriotis P, Li Y, Serra SA, Zhang Y, Yankaskas CL, He S, Valverde MA, et al.

(12) The Effects of the Anti-aging Protein Klotho on Mucociliary ClearanceFrontiers in medicineJanuary 1, 2019Garth J, Easter M, Skylar Harris E, Sailland J, Kuenzi L, Chung S, Dennis JS, Baumlin N, Adewale AT, Rowe SM, et al.

(13) TRPV4 is the temperature-sensitive ion channel of human spermeLifeJuly 2, 2018Mundt N, Spehr M, Lishko PV.

(14) Pharmacological activation of TRPV4 produces immediate cell damage and induction of apoptosis in human melanoma cells and HaCaT keratinocytesPloS oneJanuary 1, 2018Olivan-Viguera A, Garcia-Otin AL, Lozano-Gerona J, Abarca-Lachen E, Garcia-Malinis AJ, Hamilton KL, Gilaberte Y, Pueyo E, Köhler R.

(15) Functional Cooperation between KCa3.1 and TRPV4 Channels in Bronchial Smooth Muscle Cell Proliferation Associated with Chronic AsthmaFrontiers in pharmacologyJanuary 1, 2017Yu Z, Wang Y, Qin L, Chen H.

(16) Involvement of TRPV4 in Serotonin-Evoked ScratchingThe Journal of investigative dermatologyJanuary 1, 2016Akiyama T, Ivanov M, Nagamine M, Davoodi A, Carstens MI, Ikoma A, Cevikbas F, Kempkes C, Buddenkotte J, Steinhoff M, et al.

(17) Eugenol dilates mesenteric arteries and reduces systemic BP by activating endothelial cell TRPV4 channelsBritish journal of pharmacologyJuly 1, 2015Peixoto-Neves D, Wang Q, Leal-Cardoso JH, Rossoni LV, Jaggar JH.

(18) TRPV4 activates autonomic and behavioural warmth-defence responses in Wistar ratsActa physiologica (Oxford, England)June 1, 2015Vizin RC, Scarpellini Cda S, Ishikawa DT, Correa GM, de Souza CO, Gargaglioni LH, Carrettiero DC, Bícego KC, Almeida MC.

(19) Astrocyte contributions to flow/pressure-evoked parenchymal arteriole vasoconstrictionThe Journal of neuroscience : the official journal of the Society for NeuroscienceMay 27, 2015Kim KJ, Iddings JA, Stern JE, Blanco VM, Croom D, Kirov SA, Filosa JA.

(20) Hypotonic stress induces RANKL via transient receptor potential melastatin 3 (TRPM3) and vaniloid 4 (TRPV4) in human PDL cellsJournal of dental researchMarch 1, 2015Son GY, Yang YM, Park WS, Chang I, Shin DM.

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HC 067047

HC 067047 from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

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HC 067047 from Tocris Bioscience, a Bio-Techne Brand

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