PI 828 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemPI 828
CompanyTocris Bioscience, a Bio-Techne Brand
Price $122.00Supplier Page View Company Product Page
Catalog Number2814/1
Quantity1 mg
Purity98%
Molecular Weight322.36
Molecule Name2-(4-Morpholinyl)-8-(4-aminopheny)l-4H-1-benzopyran-4-one
FormulaC19H18N2O3
StorageStore at +4°C

Specifications/Features

Sizes Available: 1 mg

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Integrative metabolomics and transcriptomics analysis reveals novel therapeutic vulnerabilities in lung cancerCancer MedicineJanuary 1, 2023Jose Thaiparambil, Jianrong Dong, Sandra L. Grimm, Dimuthu Perera, Chandra Shekar R. Ambati, Vasanta Putluri, Matthew J. Robertson, Tajhal D. Patel, Brandon Mistretta, Preethi H. Gunaratne, et al.treatment with various concentrations of AZD‐6482 and PI‐828 (Sigma‐Aldrich, # 1173900‐33‐8 and Tocris‐ 2814/1) for up to 48 h. Cell viability was assessed using the XTT assay. 29 Absorbance was read at 475 nm

(2) Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1α and VEGF receptorsPloS oneJanuary 1, 2017Mahfouz N, Tahtouh R, Alaaeddine N, El Hajj J, Sarkis R, Hachem R, Raad I, Hilal G.

(3) Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytesJournal of neuroinflammationFebruary 26, 2016Liddell JR, Lehtonen S, Duncan C, Keksa-Goldsteine V, Levonen AL, Goldsteins G, Malm T, White AR, Koistinaho J, Kanninen KM.

(4) Upregulation of Nicotinic Acetylcholine Receptor alph4+beta2 through a Ligand-Independent PI3Kbeta Mechanism That Is Enhanced by TNFalpha and the Jak2/p38Mapk PathwaysPloS oneJanuary 1, 2015Rogers SW, Gahring LC.

(5) Functional kinomics identifies candidate therapeutic targets in head and neck cancerClinical cancer research : an official journal of the American Association for Cancer ResearchAugust 15, 2014Moser R, Xu C, Kao M, Annis J, Lerma LA, Schaupp CM, Gurley KE, Jang IS, Biktasova A, Yarbrough WG, et al.

(6) Multiple roles of the SO4(2-)/Cl-/OH- exchanger protein Slc26a2 in chondrocyte functionsThe Journal of biological chemistryJanuary 24, 2014Park M, Ohana E, Choi SY, Lee MS, Park JH, Muallem S.

(7) Supramolecular nanoparticles that target phosphoinositide-3-kinase overcome insulin resistance and exert pronounced antitumor efficacyCancer researchDecember 1, 2013Kulkarni AA, Roy B, Rao PS, Wyant GA, Mahmoud A, Ramachandran M, Sengupta P, Goldman A, Kotamraju VR, Basu S, et al.

(8) The expression and relaxant effect of bitter taste receptors in human bronchiRespiratory researchNovember 22, 2013Grassin-Delyle S, Abrial C, Fayad-Kobeissi S, Brollo M, Faisy C, Alvarez JC, Naline E, Devillier P.

(9) TRPV4-mediated calcium influx into human bronchial epithelia upon exposure to diesel exhaust particlesEnvironmental health perspectivesJune 1, 2011Li J, Kanju P, Patterson M, Chew WL, Cho SH, Gilmour I, Oliver T, Yasuda R, Ghio A, Simon SA, et al.

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PI 828

PI 828 from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

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PI 828 from Tocris Bioscience, a Bio-Techne Brand

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