Luzindole from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemLuzindole
CompanyTocris Bioscience, a Bio-Techne Brand
Price $225.00Supplier Page View Company Product Page
Catalog Number0877/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight292.38
Molecule NameN-Acetyl-2-benzyltryptamine
FormulaC19H20N2O
StorageStore at -20°C

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Melatonin attenuates acute and chronic itch in mice: the antioxidant and anti-inflammatory effects of melatonin receptorsAnnals of Translational MedicineSeptember 1, 2022Li Zhang, Jiang-Tao Zhang, Ya Huang, Guo-Kun Zhou, Yan Zhou, Jiang-Ping Yang, Tong LiuSigma-Aldrich (St. Louis, MO, USA).Melatonin receptor type 1 and 2 (MT1/MT2) antagonist Luzindole (Cat#0877/10) and MT2 antagonist 4-P-PDOT (Cat#1034/10) were obtained from Tocris (Bristol, UK). Sirt1 antagonist

(2) Homeostatic Plasticity Mediated by Rod-Cone Gap Junction Coupling in Retinal Degenerative Dystrophic RCS RatsFrontiers in cellular neuroscienceJanuary 1, 2017Hou B, Fu Y, Weng C, Liu W, Zhao C, Yin ZQ.

(3) Distinct roles of N-acetyl and 5-methoxy groups in the antiproliferative and neuroprotective effects of melatoninMolecular and cellular endocrinologyOctober 15, 2016Letra-Vilela R, Sánchez-Sánchez AM, Rocha AM, Martin V, Branco-Santos J, Puente-Moncada N, Santa-Marta M, Outeiro TF, Antolín I, Rodriguez C, et al.

(4) Amyloid β peptide directly impairs pineal gland melatonin synthesis and melatonin receptor signaling through the ERK pathwayFASEB journal : official publication of the Federation of American Societies for Experimental BiologyJune 1, 2015Cecon E, Chen M, Marçola M, Fernandes PA, Jockers R, Markus RP.

(5) Antinociceptive effects of novel melatonin receptor agonists in mouse models of abdominal painWorld journal of gastroenterologyFebruary 7, 2014Chen C, Fichna J, Laudon M, Storr M.

(6) Melatonin MT₁ and MT₂ receptors display different molecular pharmacologies only in the G-protein coupled stateBritish journal of pharmacologyJanuary 1, 2014Legros C, Devavry S, Caignard S, Tessier C, Delagrange P, Ouvry C, Boutin JA, Nosjean O.

(7) The melatonin agonist ramelteon induces duration-dependent clock gene expression through cAMP signaling in pancreatic INS-1 β-cellsPloS oneJanuary 1, 2014Nishiyama K, Hirai K.

(8) Heteromeric MT1/MT2 melatonin receptors modulate photoreceptor functionScience signalingOctober 8, 2013Baba K, Benleulmi-Chaachoua A, Journé AS, Kamal M, Guillaume JL, Dussaud S, Gbahou F, Yettou K, Liu C, Contreras-Alcantara S, et al.

(9) Melatonin acts through MT1/MT2 receptors to activate hypothalamic Akt and suppress hepatic gluconeogenesis in ratsAmerican journal of physiology. Endocrinology and metabolismJuly 15, 2013Faria JA, Kinote A, Ignacio-Souza LM, de Araújo TM, Razolli DS, Doneda DL, Paschoal LB, Lellis-Santos C, Bertolini GL, Velloso LA, et al.

(10) High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell deathProceedings of the National Academy of Sciences of the United States of AmericaApril 3, 2012Fox JT, Sakamuru S, Huang R, Teneva N, Simmons SO, Xia M, Tice RR, Austin CP, Myung K.

(11) NF-κB drives the synthesis of melatonin in RAW 264.7 macrophages by inducing the transcription of the arylalkylamine-N-acetyltransferase (AA-NAT) genePloS oneJanuary 1, 2012Muxel SM, Pires-Lapa MA, Monteiro AW, Cecon E, Tamura EK, Floeter-Winter LM, Markus RP.

(12) Melatonin inhibits tachykinin NK₂ receptor-triggered 5-HT release from guinea pig isolated colonic mucosaBritish journal of pharmacologyMarch 1, 2011Kojima S, Tohei A, Ikeda M.

(13) MT2 receptors mediate the inhibitory effects of melatonin on nitric oxide-induced relaxation of porcine isolated coronary arteriesThe Journal of pharmacology and experimental therapeuticsJanuary 1, 2011Tunstall RR, Shukla P, Grazul-Bilska A, Sun C, O'Rourke ST.

(14) Antinociceptive effects of melatonin in a rat model of post-inflammatory visceral hyperalgesia: a centrally mediated processPainJune 1, 2010Mickle A, Sood M, Zhang Z, Shahmohammadi G, Sengupta JN, Miranda A.

(15) Melatonin inhibits nitric oxide production by microvascular endothelial cells in vivo and in vitroBritish journal of pharmacologyMay 1, 2007Silva CL, Tamura EK, Macedo SM, Cecon E, Bueno-Alves L, Farsky SH, Ferreira ZS, Markus RP.

(16) Identification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB2 receptorBritish journal of pharmacologyJuly 1, 2005Savinainen JR, Kokkola T, Salo OM, Poso A, Järvinen T, Laitinen JT.

(17) Cyclical regulation of GnRH gene expression in GT1-7 GnRH-secreting neurons by melatoninEndocrinologyNovember 1, 2001Roy D, Angelini NL, Fujieda H, Brown GM, Belsham DD.

(18) Peripheral melatonin mediates neural stimulation of duodenal mucosal bicarbonate secretionThe Journal of clinical investigationAugust 1, 2001Sjöblom M, Jedstedt G, Flemström G.

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Luzindole

Luzindole

Luzindole from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

Citations (18)

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Luzindole from Tocris Bioscience, a Bio-Techne Brand

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