SL 327 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemSL 327
CompanyTocris Bioscience, a Bio-Techne Brand
Price $147.00Supplier Page View Company Product Page
Catalog Number1969/1
Quantity1 mg (also 10 mg, 50 mg)
Purity98%
Molecular Weight335.35
Molecule Nameα-[Amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)benzeneacetonitrile
FormulaC16H12F3N3S
StorageDesiccate at +4°C

Specifications/Features

Sizes Available: 1 mg (also 10 mg, 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) β-Arrestin–dependent ERK signaling reduces anxiety-like and conditioned fear–related behaviors in miceScience SignalingAugust 4, 2021Mee Jung Ko, Terrance Chiang, Arbaaz A. Mukadam, Grace E. Mulia, Anna M. Gutridge, Angel Lin, Julia A. Chester, Richard M. van Rijnsaline pH5-6. TAN67 (#092110, Tocris, Thermo Fisher Scientific) was diluted in sterile saline. SL327 (#19691, Tocris, Thermo Fisher Scientific) was diluted in 5% DMSO, 10% Cremophore (Millipore Sigma, Burlington,

(2) The Protective Effect of Insulin on Rat Cortical Neurons in Oxidative Stress and Its Dependence on the Modulation of Akt, GSK-3beta, ERK1/2, and AMPK ActivitiesInternational journal of molecular sciencesJuly 29, 2019Zakharova IO, Sokolova TV, Bayunova LV, Zorina II, Rychkova MP, Shpakov AO, Avrova NF.

(3) A Cross Talk between Neuronal Urokinase-type Plasminogen Activator (uPA) and Astrocytic uPA Receptor (uPAR) Promotes Astrocytic Activation and Synaptic Recovery in the Ischemic BrainThe Journal of neuroscience : the official journal of the Society for NeuroscienceOctober 25, 2017Diaz A, Merino P, Manrique LG, Ospina JP, Cheng L, Wu F, Jeanneret V, Yepes M.

(4) Negative regulation of ERK1/2 by PI3K is required for the protective effects of Pyropia yezoensis peptide against perfluorooctane sulfonate-induced endoplasmic reticulum stressMolecular medicine reportsMay 1, 2017Oh JH, Kim EY, Choi YH, Nam TJ.

(5) Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathyPLoS geneticsMarch 1, 2017Altmüller F, Pothula S, Annamneedi A, Nakhaei-Rad S, Montenegro-Venegas C, Pina-Fernández E, Marini C, Santos M, Schanze D, Montag D, et al.

(6) IMPACT OF CROP CONDITION REPORTS ON NATIONAL AND LOCAL WHEAT MARKETSJournal of Agricultural and Applied EconomicsFebruary 1, 2017RYAN BAIN, T. RANDALL FORTENBERYand R. Roll. “The Adjustment of Stock Prices to New Information.” International Economic Review 10,1(1969):1–21. Fortenbery, T.R., and D.A. Sumner. “The Effects of USDA Reports in Futures and Options Markets.”

(7) Cell type-dependent Erk-Akt pathway crosstalk regulates the proliferation of fetal neural progenitor cellsScientific reportsMay 23, 2016Rhim JH, Luo X, Gao D, Xu X, Zhou T, Li F, Wang P, Wong ST, Xia X.

(8) Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytesJournal of neuroinflammationFebruary 26, 2016Liddell JR, Lehtonen S, Duncan C, Keksa-Goldsteine V, Levonen AL, Goldsteins G, Malm T, White AR, Koistinaho J, Kanninen KM.

(9) Targeting β-arrestin2 in the treatment of L-DOPA-induced dyskinesia in Parkinson's diseaseProceedings of the National Academy of Sciences of the United States of AmericaMay 12, 2015Urs NM, Bido S, Peterson SM, Daigle TL, Bass CE, Gainetdinov RR, Bezard E, Caron MG.

(10) Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndromeNature neuroscienceDecember 1, 2014Lee YS, Ehninger D, Zhou M, Oh JY, Kang M, Kwak C, Ryu HH, Butz D, Araki T, Cai Y, et al.

(11) G Protein and β-arrestin signaling bias at the ghrelin receptorThe Journal of biological chemistryNovember 28, 2014Evron T, Peterson SM, Urs NM, Bai Y, Rochelle LK, Caron MG, Barak LS.

(12) Spaced training rescues memory and ERK1/2 signaling in fragile X syndrome model miceProceedings of the National Academy of Sciences of the United States of AmericaNovember 25, 2014Seese RR, Wang K, Yao YQ, Lynch G, Gall CM.

(13) mGluR1-mediated excitation of cerebellar GABAergic interneurons requires both G protein-dependent and Src-ERK1/2-dependent signaling pathwaysPloS oneJanuary 1, 2014Kubota H, Nagao S, Obata K, Hirono M.

(14) Inhibition of a novel specific neuroglial integrin signaling pathway increases STAT3-mediated CNTF expressionCell communication and signaling : CCSMay 21, 2013Keasey MP, Kang SS, Lovins C, Hagg T.

(15) A metabolic perturbation by U0126 identifies a role for glutamine in resveratrol-induced cell deathCancer biology & therapyDecember 1, 2011Freeman MR, Kim J, Lisanti MP, Di Vizio D.

(16) Erk1/2 inhibit synaptic vesicle exocytosis through L-type calcium channelsThe Journal of neuroscience : the official journal of the Society for NeuroscienceMarch 23, 2011Subramanian J, Morozov A.

(17) A dopamine D1 receptor-dependent β-arrestin signaling complex potentially regulates morphine-induced psychomotor activation but not reward in miceNeuropsychopharmacology : official publication of the American College of NeuropsychopharmacologyFebruary 1, 2011Urs NM, Daigle TL, Caron MG.

(18) Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndromeThe Journal of neuroscience : the official journal of the Society for NeuroscienceNovember 17, 2010Osterweil EK, Krueger DD, Reinhold K, Bear MF.

(19) Genetic targeting of ERK1 suggests a predominant role for ERK2 in murine pain modelsThe Journal of neuroscience : the official journal of the Society for NeuroscienceAugust 25, 2010Alter BJ, Zhao C, Karim F, Landreth GE, Gereau RW 4th.

(20) Increased operant responding for ethanol in male C57BL/6J mice: specific regulation by the ERK1/2, but not JNK, MAP kinase pathwayPsychopharmacologyMay 1, 2009Faccidomo S, Besheer J, Stanford PC, Hodge CW.

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SL 327

SL 327 from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

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SL 327 from Tocris Bioscience, a Bio-Techne Brand

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