Dihydro-b-erythroidine hydrobromide from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemDihydro-b-erythroidine hydrobromide
CompanyTocris Bioscience, a Bio-Techne Brand
Price $298.00Supplier Page View Company Product Page
Catalog Number2349/10
Purity98%
Molecular Weight356.26
Molecule Name(2S,13bS)-2-Methoxy-2,3,5,6,8,9,10,13-octahydro-1H,12H-benzo[i]pyrano[3,4-g]indolizin-12-one hydrobromide
FormulaC16H21NO3.HBr
StorageDesiccate at RT
Quantity10 mg (also 50 mg)

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Dual cholinergic mechanisms for sculpting striatal dopamine in vivobioRxivDecember 21, 2025Dylan R. Flink, Nicholas G. Faturos, Haowei Zhang, Arif A. HamidDihydro-β-erythroidine hydrobromide (DHβE) for β2-subunit-containing nicotinic receptor blockade (1 mg/kg; Tocris cat#: 234910); scopolamine for broad muscarinic receptor blockade (1 or 5 mg/kg; Sigma-Aldrich cat#: S0929); mecamylamine

(2) The early excitatory action of striatal cholinergic-GABAergic microcircuits conditions the subsequent GABA inhibitory shiftCommunications BiologyJuly 14, 2023Natalia Lozovaya, Sanaz Eftekhari, Constance HammondTocris Bioscience, Ref. 1029/5) and Dihydro-β-erythroidine hydrobromide (DHβE, 10 μM, Tocris Bioscience, Ref. 2349/10) were directly added to the perfusion solutions. Statistics and reproducibility Data were obtained

(3) Spatially displaced excitation contributes to the encoding of interrupted motion by a retinal direction-selective circuiteLifeJune 7, 2021Jennifer Ding, Albert Chen, Janet Chung, Hector Acaron Ledesma, Mofei Wu, David M Berson, Stephanie E Palmer, Wei Weibath during electrophysiology recordings. 8 mM Dihydro-b-erythroidine hydrobromide (DHbE; Tocris, Cat#2349); 10 mM SR 9551 hydrobromide (gabazine; Tocris, Cat #1262); 100 mM Meclofenamic acid sodium salt (MFA; Sigma-Aldrich.

(4) Polysynaptic inhibition between striatal cholinergic interneurons shapes their network activity patterns in a dopamine-dependent mannerNature communicationsOctober 9, 2020Dorst MC, Tokarska A, Zhou M, Lee K, Stagkourakis S, Broberger C, Masmanidis S, Silberberg G.

(5) Nicotinic acetylcholine receptors: Ex-vivo expression of functional, non-hybrid, heteropentameric receptors from a marine arthropod, Lepeophtheirus salmonisPLoS pathogensJuly 1, 2020Rufener L, Kaur K, Sarr A, Aaen SM, Horsberg TE.

(6) Relaxation of synaptic inhibitory events as a compensatory mechanism in fetal SOD spinal motor networkseLifeDecember 23, 2019Pascal Branchereau, Elodie Martin, Anne-Emilie Allain, William Cazenave, Laura Supiot, Fara Hodeib, Amandine Laupénie, Urvashi Dalvi, Hongmei Zhu, Daniel CattaertSigma Cat#2379 10 mM Chemical compound, drug Dihydro-b-erythroidine hydrobromide Bio-techne, France Cat#2349/10 5 mM Chemical compound, drug Strychnine Hemisulfate salt Millipore Sigma Cat#S7001 3 mM Chemical compound,

(7) Neural mechanisms of contextual modulation in the retinal direction selective circuitNature communicationsJune 3, 2019Huang X, Rangel M, Briggman KL, Wei W.

(8) Local GABA_A Receptor-Mediated Suppression of Dopamine Release within the Nucleus AccumbensACS chemical neuroscienceApril 17, 2019Brodnik ZD, Batra A, Oleson EB, España RA.

(9) Pauses in Cholinergic Interneuron Activity Are Driven by Excitatory Input and Delayed Rectification, with Dopamine ModulationNeuronJune 6, 2018Zhang YF, Reynolds JNJ, Cragg SJ.

(10) GABAergic inhibition in dual-transmission cholinergic and GABAergic striatal interneurons is abolished in Parkinson diseaseNature communicationsApril 12, 2018Lozovaya N, Eftekhari S, Cloarec R, Gouty-Colomer LA, Dufour A, Riffault B, Billon-Grand M, Pons-Bennaceur A, Oumar N, Burnashev N, et al.Tocris Bioscience, Ref. 1029/5), and dihydro-β-erythroidine hydrobromide (10 μM, Tocris Bioscience, Ref. 2349/10). For in vivo experiments, bumetanide pretreatment (3 mg kg−1) was given to mice in drinking water during

(11) Differential effects of α4β2 nicotinic receptor antagonists and partial-agonists on contextual fear extinction in male C57BL/6 micePsychopharmacologyApril 1, 2018Kutlu MG, Tumolo JM, Cann C, Gould TJ.

(12) Inhibition of peripheral macrophages by nicotinic acetylcholine receptor agonists suppresses spinal microglial activation and neuropathic pain in mice with peripheral nerve injuryJournal of neuroinflammationMarch 27, 2018Kiguchi N, Kobayashi D, Saika F, Matsuzaki S, Kishioka S.

(13) TRPV1 regulates excitatory innervation of OLM neurons in the hippocampusNature communicationsJuly 19, 2017Hurtado-Zavala JI, Ramachandran B, Ahmed S, Halder R, Bolleyer C, Awasthi A, Stahlberg MA, Wagener RJ, Anderson K, Drenan RM, et al.

(14) Selective and regulated trapping of nicotinic receptor weak base ligands and relevance to smoking cessationeLifeJuly 18, 2017Govind AP, Vallejo YF, Stolz JR, Yan JZ, Swanson GT, Green WN.

(15) Differential processing of thalamic information via distinct striatal interneuron circuitsNature communicationsJune 12, 2017Assous M, Kaminer J, Shah F, Garg A, Koós T, Tepper JM.

(16) Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cellseLifeFebruary 14, 2017Sternfeld MJ, Hinckley CA, Moore NJ, Pankratz MT, Hilde KL, Driscoll SP, Hayashi M, Amin ND, Bonanomi D, Gifford WD, et al.creatinine sulfate monohydrate (5-HT, Sigma H7752), 50 µM dihydro-β-erythroidine hydrobromide (DHβE, Tocris 2349), 10 μM mecamylamine hydrochloride (MLA, Tocris 2843), 10 μM CNQX disodium salt (Tocris 1045), 1 μM strychnine

(17) Plasticity in Brainstem Mechanisms of Pain Modulation by Nicotinic Acetylcholine Receptors in the RateNeuroJanuary 1, 2017Jareczek FJ, White SR, Hammond DL.

(18) Nicotinic and opioid receptor regulation of striatal dopamine D2-receptor mediated transmissionScientific reportsNovember 25, 2016Mamaligas AA, Cai Y, Ford CP.

(19) Nicotine evokes kinetic tremor by activating the inferior olive via α7 nicotinic acetylcholine receptorsBehavioural brain researchNovember 1, 2016Kunisawa N, Iha HA, Shimizu S, Tokudome K, Mukai T, Kinboshi M, Serikawa T, Ohno Y.

(20) A cholinergic basal forebrain feeding circuit modulates appetite suppressionNatureOctober 13, 2016Herman AM, Ortiz-Guzman J, Kochukov M, Herman I, Quast KB, Patel JM, Tepe B, Carlson JC, Ung K, Selever J, et al.

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