Anisomycin from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemAnisomycin
CompanyTocris Bioscience, a Bio-Techne Brand
Price $133.00Supplier Page View Company Product Page
Catalog Number1290/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight265.31
Molecule Name(2R,3S,4S)-2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate
FormulaC14H19NO4
StorageStore at +4°C

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Dopamine increases protein synthesis in hippocampal neurons enabling dopamine-dependent LTPElifeMarch 10, 2025Tania Fuchsberger, Imogen Stockwell, Matty Woods, Zuzanna Brzosko, Ingo H Greger, Ole Paulsen(Tocris Bioscience 1078), 10 µM CHX (Tocris Bioscience 0970), 0.5 mM AM (stock solution in EtOH; Tocris Bioscience 1290/10), 30 µM Rp-cAMPS (Tocris Bioscience 1337). Protein synthesis was measured using a PMY-based labelling

(2) Postsynaptic burst reactivation of hippocampal neurons enables associative plasticity of temporally discontiguous inputseLifeOctober 13, 2022Tanja Fuchsberger, Claudia Clopath, Przemyslaw Jarzebowski, Zuzanna Brzosko, Hongbing Wang, Ole Paulsen,PKA inhibitor fragment (6-22) amide,Tocris Bioscience,1904/1,1 µM "Chemical compound, drug",Anisomycin,Tocris Bioscience,1290/10,0.5 mM "Chemical compound, drug",MK801,Tocris Bioscience,0924,1 mM "Software, algorithm",Igor Pro

(3) Effects of the presence and absence of amino acids on translation, signaling, and long‐term depression in hippocampal slices from Fmr1 knockout miceJournal of NeurochemistryDecember 1, 2019Spencer K. Cooke, Jacob Russin, Kristen Moulton, Jeffrey Nadel, Inna Loutaev, Qinhua Gu, Zheng Li, Carolyn Beebe SmithNo. 0342/1) and 2-p-methoxyphenylmethyl-3-acetoxy-4-hydroxypyrrolidine (anisomycin; Tocris) (Cat. No. 1290/10). Other reagents used include ethylenedinitrilotetraacetic acid (EDTA; 0.5 M, pH 8.0; Quality Biological,

(4) Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer's disease model miceThe Journal of clinical investigationFebruary 1, 2019Beckelman BC, Yang W, Kasica NP, Zimmermann HR, Zhou X, Keene CD, Ryazanov AG, Ma T.

(5) Enhanced Glycolysis Supports Cell Survival in EGFR-Mutant Lung Adenocarcinoma by Inhibiting Autophagy-Mediated EGFR DegradationCancer researchAugust 15, 2018Kim JH, Nam B, Choi YJ, Kim SY, Lee JE, Sung KJ, Kim WS, Choi CM, Chang EJ, Koh JS, et al.

(6) Epigenetic regulation by G9a/GLP complex ameliorates amyloid-beta 1-42 induced deficits in long-term plasticity and synaptic tagging/capture in hippocampal pyramidal neuronsAging cellOctober 1, 2017Sharma M, Dierkes T, Sajikumar S.

(7) Metaplasticity mechanisms restore plasticity and associativity in an animal model of Alzheimer's diseaseProceedings of the National Academy of Sciences of the United States of AmericaMay 23, 2017Li Q, Navakkode S, Rothkegel M, Soong TW, Sajikumar S, Korte M.

(8) Direct visualization of newly synthesized target proteins in situNature methodsMay 1, 2015tom Dieck S, Kochen L, Hanus C, Heumüller M, Bartnik I, Nassim-Assir B, Merk K, Mosler T, Garg S, Bunse S, et al.

(9) Extracellular glutamate exposure facilitates group I mGluR-mediated epileptogenesis in the hippocampusThe Journal of neuroscience : the official journal of the Society for NeuroscienceJanuary 7, 2015Zhao W, Chuang SC, Young SR, Bianchi R, Wong RK.

(10) Suppression of MAPK/JNK-MTORC1 signaling leads to premature loss of organelles and nuclei by autophagy during terminal differentiation of lens fiber cellsAutophagyJuly 1, 2014Basu S, Rajakaruna S, Reyes B, Van Bockstaele E, Menko AS.

(11) Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNAMolecular and cellular biologyFebruary 1, 2014Dobrikov MI, Shveygert M, Brown MC, Gromeier M.

(12) Small molecule screen yields inhibitors of Pseudomonas homoserine lactone-induced host responsesCellular microbiologyJanuary 1, 2014Valentine CD, Zhang H, Phuan PW, Nguyen J, Verkman AS, Haggie PM.

(13) Phosphorylation of FMRP and alterations of FMRP complex underlie enhanced mLTD in adult rats triggered by early life seizuresNeurobiology of diseaseNovember 1, 2013Bernard PB, Castano AM, O'Leary H, Simpson K, Browning MD, Benke TA.

(14) Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficitsNature neuroscienceSeptember 1, 2013Ma T, Trinh MA, Wexler AJ, Bourbon C, Gatti E, Pierre P, Cavener DR, Klann E.

(15) Long-term potentiation of synaptic transmission in the adult mouse insular cortex: multielectrode array recordingsJournal of neurophysiologyJuly 1, 2013Liu MG, Kang SJ, Shi TY, Koga K, Zhang MM, Collingridge GL, Kaang BK, Zhuo M.

(16) SynGAP regulates protein synthesis and homeostatic synaptic plasticity in developing cortical networksPloS oneJanuary 1, 2013Wang CC, Held RG, Hall BJ.

(17) Long lasting protein synthesis- and activity-dependent spine shrinkage and elimination after synaptic depressionPloS oneJanuary 1, 2013Ramiro-Cortés Y, Israely I.

(18) Metabolic labeling with noncanonical amino acids and visualization by chemoselective fluorescent taggingCurrent protocols in cell biologySeptember 1, 2012Tom Dieck S, Müller A, Nehring A, Hinz FI, Bartnik I, Schuman EM, Dieterich DC.

(19) Brain-derived neurotrophic factor activation of CaM-kinase kinase via transient receptor potential canonical channels induces the translation and synaptic incorporation of GluA1-containing calcium-permeable AMPA receptorsThe Journal of neuroscience : the official journal of the Society for NeuroscienceJune 13, 2012Fortin DA, Srivastava T, Dwarakanath D, Pierre P, Nygaard S, Derkach VA, Soderling TR.

(20) High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell deathProceedings of the National Academy of Sciences of the United States of AmericaApril 3, 2012Fox JT, Sakamuru S, Huang R, Teneva N, Simmons SO, Xia M, Tice RR, Austin CP, Myung K.

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Anisomycin

Anisomycin from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

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Anisomycin from Tocris Bioscience, a Bio-Techne Brand

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