MRS 2365 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemMRS 2365
CompanyTocris Bioscience, a Bio-Techne Brand
Price $528.00Supplier Page View Company Product Page
Catalog Number2157/1
Quantity1 mg
Purity98%
Molecular Weight549.28
Molecule Name[[(1R,2R,3S,4R,5S)-4-[6-Amino-2-(methylthio)-9H-purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hex-1-yl]methyl] diphosphoric acid mono ester trisodium salt
FormulaC13H16N5O9P2SNa3
StorageStore at -80°C

Specifications/Features

Sizes Available: 1 mg

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Inhibiting the LPS-induced enhancement of mEPSC frequency in superficial dorsal horn neurons may serve as an electrophysiological model for alleviating painScientific reportsNovember 5, 2019Yang CT, Hung SY, Hsu SF, MacDonald I, Lin JG, Luo ST, Lin PL, Chen YH.

(2) P2Y1 Purinergic Receptor Modulate Axon Initial Segment Initial DevelopmentFrontiers in cellular neuroscienceJanuary 1, 2019Zhang W, Bonadiman A, Ciorraga M, Benitez MJ, Garrido JJ.

(3) P2Y1R is involved in visceral hypersensitivity in rats with experimental irritable bowel syndromeWorld journal of gastroenterologySeptember 14, 2017Wu J, Cheng Y, Zhang R, Liu D, Luo YM, Chen KL, Ren S, Zhang J.hypersensitivity upon intervention with P2Y1R agonist or antagonist Drug preparation: The P2Y1R agonist MRS2365 (2157/1, R&D Systems China Co., Ltd., China) and the antagonist MRS2179 (ab120414, ABCAM Corporation) were dissolved

(4) RASA3 is a critical inhibitor of RAP1-dependent platelet activationThe Journal of clinical investigationApril 1, 2015Stefanini L, Paul DS, Robledo RF, Chan ER, Getz TM, Campbell RA, Kechele DO, Casari C, Piatt R, Caron KM, et al.

(5) Impaired cognition after stimulation of P2Y1 receptors in the rat medial prefrontal cortexNeuropsychopharmacology : official publication of the American College of NeuropsychopharmacologyJanuary 1, 2015Koch H, Bespalov A, Drescher K, Franke H, Krügel U.

(6) Platelet-derived growth factor receptor-α-positive cells and not smooth muscle cells mediate purinergic hyperpolarization in murine colonic musclesAmerican journal of physiology. Cell physiologySeptember 15, 2014Kurahashi M, Mutafova-Yambolieva V, Koh SD, Sanders KM.

(7) Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruliAmerican journal of physiology. Cell physiologyNovember 15, 2013Ilatovskaya DV, Palygin O, Levchenko V, Staruschenko A.

(8) Functional expression of purinergic P2 receptors and transient receptor potential channels by the human urotheliumAmerican journal of physiology. Renal physiologyAugust 1, 2013Shabir S, Cross W, Kirkwood LA, Pearson JF, Appleby PA, Walker D, Eardley I, Southgate J.

(9) The role of P2Y(14) and other P2Y receptors in degranulation of human LAD2 mast cellsPurinergic signallingMarch 1, 2013Gao ZG, Wei Q, Jayasekara MP, Jacobson KA.

(10) Facilitation of transmitter release from rat sympathetic neurons via presynaptic P2Y(1) receptorsBritish journal of pharmacologyNovember 1, 2011Chandaka GK, Salzer I, Drobny H, Boehm S, Schicker KW.

(11) Astrocytic P2Y(1) receptor is involved in the regulation of cytokine/chemokine transcription and cerebral damage in a rat model of cerebral ischemiaJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismSeptember 1, 2011Kuboyama K, Harada H, Tozaki-Saitoh H, Tsuda M, Ushijima K, Inoue K.

(12) The scaffold protein NHERF2 determines the coupling of P2Y1 nucleotide and mGluR5 glutamate receptor to different ion channels in neuronsThe Journal of neuroscience : the official journal of the Society for NeuroscienceAugust 18, 2010Filippov AK, Simon J, Barnard EA, Brown DA.

(13) Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in mouse skeletal muscle by P2Y6 receptor activationPharmacological researchSeptember 1, 2008Mamedova LK, Wang R, Besada P, Liang BT, Jacobson KA.

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MRS 2365

MRS 2365 from Tocris Bioscience, a Bio-Techne Brand

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Specifications/Features

Tocris Bioscience, a Bio-Techne Brand

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MRS 2365 from Tocris Bioscience, a Bio-Techne Brand

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