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Protein Biochemistry
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JZL 195
JZL 195 from Cayman Chemical
Be the first to write a review!
Citations:
(3)
Supplier Page
Supplier Page from
Cayman Chemical for
JZL 195
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Description
A potent inhibitor of both FAAH and MAGL (IC50s = 2 and 4 nM, respectively); poorly inhibits other brain serine hydrolases
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
JZL 195
Company
Cayman Chemical
Price
$898.00
Supplier Page
View Company Product Page
Catalog Number
13668
Quantity
100 mg
Research Area
Cannabinoid Research, Endocannabinoids, Neuroscience, Pain Research
Format
A crystalline solid
Molecular Weight
433.5
Purity
≥98%
Storage
-20
Formula
C24H23N3O5
Origin
USA
Type
Inhibitors
Add to Compare List
Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (3)
(1)
Reversal of diet-induced hepatic steatosis by peripheral CB1 receptor blockade in mice is p53/miRNA-22/SIRT1/PPARα dependent
Molecular metabolism
December 1, 2020
Azar S, Udi S, Drori A, Hadar R, Nemirovski A, Vemuri KV, Miller M, Sherill-Rofe D, Arad Y, Gur-Wahnon D,
et al
.
Drug Discovery
, Northeastern University, Boston, MA, USA. ACEA (Cat#
91054
), PFT-α (Cat#
16209
), and JZL195 (Cat#
13668
) were purchased from
Cayman Chemical
.
HU-210
and
HU-308
were kindly provided by Prof. Raphael Mechoulam
(2)
Endocannabinoid degradation inhibitors ameliorate neuronal and synaptic alterations following traumatic brain injury
Journal of Neurophysiology
February 1, 2020
Elizabeth A. Fucich, Zachary F. Stielper, Heather L. Cancienne, Scott Edwards, Nicholas W. Gilpin, Patricia E. Molina, Jason W. Middleton
demonstrates high selectivity (⬎7,500 fold) for FAAH over MAGL (Kathuria et al. 2003). JZL195 (item no.
13668
;
Cayman Chemical
, Ann Arbor, MI) was used to dually
inhibit
MAGL and FAAH. JZL195 has displayed
IC50
(3)
Targeting Peripheral CB1 Receptors Reduces Ethanol Intake via a Gut-Brain Axis
Cell Metabolism
June 1, 2019
Grzegorz Godlewski et al.
Inc.",DLM-215–1 "1,2,3,4-[13C4] Octanoic acid","Cambridge Isotope Laboratories, Inc.",CLM-2721–0.25
JZL 195
,
Cayman CHEMICAL
,
13668
Hydrochloric acid
(HCI),Avantor - Macron Fine Chemicals,2612–14
Sucrose
,
MilliporeSigma
,
S7903
Saccharin,MilliporeSigma,109185 Quinine
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JZL 195 from Cayman Chemical
Supplier Page
View Company Product Page
$898.00
Product Specs
Company Info
Citations
Reviews
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