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Protein Biochemistry
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Dexamethasone
Dexamethasone from Cayman Chemical
Be the first to write a review!
Citations:
(28)
Supplier Page
Supplier Page from
Cayman Chemical for
Dexamethasone
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Description
A synthetic glucocorticoid that binds the human glucocorticoid receptor with a higher affinity than a natural ligand, cortisol (Kd = 5 vs. 17 nM, respectively); has anti-inflammatory effects
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Dexamethasone
Company
Cayman Chemical
Price
$65.00
Supplier Page
View Company Product Page
Catalog Number
11015
Quantity
500 mg
Research Area
Autoimmunity, Endocrinology & Metabolism, Glucocorticoids & Mineralocorticoids, Hormones & Receptors, Immunology & Inflammation, Innate Immunity, Neuroscience, Ophthalmology, Rheumatoid Arthritis
Format
A crystalline solid
Molecular Weight
392.5
Purity
≥98%
Origin
USA
Formula
C22H29FO5
Storage
-20
Add to Compare List
Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (28)
(1)
Development of an in vitro metabolic dysfunction-associated steatohepatitis model to investigate altered drug metabolizing enzymes, transport proteins, and hepatobiliary disposition
Frontiers in Pharmacology
January 12, 2026
William A. Murphy, Sarina Kyburz, Henry Ho, Matthew Shane Loop, John K. Fallon, Jacqueline B. Tiley, Thomas Kralj, Kim L. R. Brouwer
#
200–06
) were purchased from
PeproTech
(Cranbury, NJ).
Palmitic acid
(PA; #
10006627
), dexamethasone (#
11015
), and imatinib (#
13139
) were purchased from
Cayman Chemicals
(Ann Arbor, MI). BODIPY™ 493/503 (#D3922),
(2)
Chemical characterization of Jing Guan Fang and its application in alleviating coronavirus envelope protein-induced proinflammatory responses in vitro and in vivo
Journal of Traditional and Complementary Medicine
January 1, 2026
Hsin Yeh, Li-Lan Liao, Wei-Hung Hsu, Yu Jing, Chung-Hua Hsu, Muh-Hwa Yang, Tung-Yi Lin
Protein assay dye reagent concentrate
(Cat#
5000006
) was purchased from
Bio-Rad
(Hercules, California, USA).
Dexamethasone
(DXT, Cat#
11015
) was purchased from
Cayman Chemical
(Ann Arbor, MI, USA). Crystal violet (Cat# 131762.1608), sulfuric
(3)
Effects of Luteolin and Apigenin on Adipogenesis Markers PPARγ and FABP4 and Thermogenesis Marker UCP1 in 3T3-L1 Preadipocyte Cell Line
International Journal of Molecular Sciences
December 22, 2025
Gülcan Uysal Yeler, Ayşegül Sivaslıoğlu, Tuğba Gülsün, Zeynep Göktaş
3-isobutyl-1-methylxanthine (IBMX, 0.5 M;
Sigma
, Burlington, MA, USA), dexamethasone (DEX, 1 µM; Item No.
11015
,
Cayman
, Ann Arbor, MI, USA), and insulin (10 µg/mL, insulin from bovine pancreas;
I6634
,
Sigma
, USA).
(4)
Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling
Cell Stem Cell
October 2, 2025
Biao Huang, Pedro Medina, Jincan He, Zipeng Zeng, Sunghyun Kim, Janet Romo, Kari Koppitch, Chennan C. Zhang, Georgina Gyarmati, Yohan Park,
et al.
30996
Hydrocortisone 21-hemisuccinate (sodium salt
),
Cayman Chemical
,Cat#
18226
Dexamethasone
,
Cayman Chemical
,Cat#
11015
25-hydroxy Vitamin D3
,
Cayman Chemical
,Cat#
9000683
-1MG Parathyroid hormone (1-34),ApexBio,Cat# A1129-5MG (
Z)-4-Hydroxytamoxifen
(5)
A genome-wide screen identifies genes required for erythroid differentiation
Nat Commun
April 12, 2025
Greggory Myers, Ann Friedman, Lei Yu, Narges Pourmandi, Claire Kerpet, Masaki A. Ito, Rilie Saba, Vi Tang, Ayse Bilge Ozel, Ingrid L. Bergin,
et al.
recombinant
human
stem cell
factor (50 ng/mL; R&D, cat. #255-SC-01M), dexamethasone (1 mM;
Cayman
, cat. #
11015
), doxycycline (1 mg/mL;
Sigma
, cat. #D9891), and penicillin-streptomycin (100 U/mL;
ThermoFisher
, cat.
(6)
miR-10a regulates cell death and inflammation in adipose tissue of male mice with diet-induced obesity
Molecular metabolism
December 1, 2024
Lee S, Cho YK, Kim H, Choi C, Kim S, Lee YH.
medium (growth medium containing
IBMX
(
Sigma
, 0.5 mM, cat#
I5879
-1G), dexamethasone (
Cayman
, 1 μM, cat#
11015
), insulin (
Sigma
, 10 μg/mL, cat#
I9278
), indomethacin (
Cayman
, 0.125 mM, cat#
70270
) and triiodothyronine
(7)
Alleviating iatrogenic effects of paclitaxel via antiinflammatory treatment
Vascular Medicine
August 1, 2024
Mengwei Zhang, Saran Lotfollahzadeh, Nagla Elzinad, Xiaosheng Yang, Murad Elsadawi, Adam C Gower, Mostafa Belghasem, Tarek Shazly, Vijaya B Kolachalama, Vipul C Chitalia
1 h before use. Drugs PTX (cat no. P9600; LC Laboratories, USA) and dexamethasone (DEX) (cat no.
11015
;
Cayman Chemical Company
, USA) were dissolved in
dimethyl sulfoxide (DMSO
) (cat no.
D8418
–250ML;
Sigma
).
Cell viability assay
(8)
SHP2 regulates adipose maintenance and adipocyte-pancreatic cancer cell crosstalk via PDHA1
Journal of cell communication and signaling
September 1, 2023
Olou AA, Ambrose J, Jack JL, Walsh M, Ruckert MT, Eades AE, Bye BA, Dandawate P, VanSaun MN.
with 10% FBS, Insulin (cat#
I0516
,
Sigma
; 1 µg/ml for
3T3-L1
, 3 µg/ml for adMSC),
Dexamethasone
(cat#
11015
Cayman Chemicals
; 10 µg/ml),
Rosiglitazone
(cat#
71740
,
Cayman Chemicals
; 3 µg/ml) and
IBMX
(cat#
I5879
,
(9)
Differential roles of insulin receptor in adipocyte progenitor cells in mice
Molecular and Cellular Endocrinology
August 1, 2023
Yexian Yuan, Zuoxiao Shi, Shaolei Xiong, Ruoci Hu, Qing Song, Zhenyuan Song, Sang-Ging Ong, Yuwei Jiang
containing 10% FBS, insulin (1 μg/ml,
Sigma-Aldrich
,
I0516
), dexamethasone (5 μM,
Cayman Chemicals
,
11015
), and isobutylmethylxanthine (0.5 mM,
Sigma-Aldrich
,
I5879
) for 3 days. Beige adipogenesis was induced
(10)
Alleviating iatrogenic effects of paclitaxel via anti-inflammatory treatment
Research Square
May 26, 2023
Mengwei Zhang, Saran Lotfollahzadeh, Nagla Elzinad, Xiaosheng Yang, Murad Elsadawi, Adam Gower, Mostafa Belghasem, Tarek Shazly, Vijaya B. Kolachalama, Vipul Chitalia
before use. Drugs
Paclitaxel
(PTX) (Cat No. P9600; LC Laboratories) and dexamethasone (DEX) (Cat No.
11015
;
Cayman Chemical Company
) were dissolved in DMSO (Cat No.
D8418
–250ML;
Sigma
).
Cell viability assay
ECs
(11)
Establishment of Skeletal Myogenic Progenitors from Non-Human Primate Induced Pluripotent Stem Cells
Cells
April 13, 2023
Baik J, Ortiz-Cordero C, Magli A, Azzag K, Crist SB, Yamashita A, Kiley J, Selvaraj S, Mondragon-Gonzalez R, Perrin E,
et al
.
Chemical #
19396
), 10 µM forskolin (
Cayman Chemical
#
11018
), and 10 µM dexamethasone (
Cayman Chemical
#
11015
) [17]. RFP-labeled NHP iPAX7 CyMN.2
iPS cells
were generated by transducing these cells with the lentiviral
(12)
Crosstalk of hepatocyte nuclear factor 4a and glucocorticoid receptor in the regulation of lipid metabolism in mice fed a high-fat-high-sugar diet
Lipids in Health and Disease
December 1, 2022
Hong Lu, Xiaohong Lei, Rebecca Winkler, Savio John, Devendra Kumar, Wenkuan Li, Yazen Alnouti
Addgene), SHP, and/or the pCMX backbone vector to add up the total DNA vectors to 100 ng.
Dexamethasone
(#
11015
,
Cayman Chemical
) (10 nM) was added 1 h after cells were
transfected
with the GR expression vector.
(13)
Anti-obesity effects of the dual-active adenosine A2A/A3 receptor-ligand LJ-4378
International Journal of Obesity
December 1, 2022
Kyungmin Kim, Hyeonyeong Im, Yeonho Son, Minjae Kim, Sushil Kumar Tripathi, Lak Shin Jeong, Yun-Hee Lee
Arbor, MI, USA), 0.125 mM indomethacin (
Cayman
,
70270
, Ann Arbor, MI, USA), 1 μM dexamethasone (
Cayman
,
11015
, Ann Arbor, MI, USA), 1 μg/mL insulin (
Sigma
,
I9278
, St. Louis, MO, USA), and 1 nM triiodothyronine
(14)
Adipocyte lysoplasmalogenase TMEM86A regulates plasmalogen homeostasis and protein kinase A-dependent energy metabolism
Nature communications
July 14, 2022
Cho YK, Yoon YC, Im H, Son Y, Kim M, Saha A, Choi C, Lee J, Lee S, Kim JH,
et al
.
differentiation medium containing
IBMX
(
Sigma
, 0.5 mM, cat#
I5879
-1G), dexamethasone (
Cayman
, 1 μM, cat#
11015
), insulin (
Sigma
, 10 μg/mL, cat#
I9278
), indomethacin (
Cayman
, 0.125 mM, cat#
70270
) and triiodothyronine
(15)
Antiapoptotic Protein FAIM2 is targeted by miR-3202, and DUX4 via TRIM21, leading to cell death and defective myogenesis
Cell death & disease
April 25, 2022
Soliman HAN, Toso EA, Darwish IE, Ali SM, Kyba M.
(CX30324, Gibco Gaithersburg, MD), 10 ng/ml hb-FGF (PeproTech, Cranbury, NJ) and 100 nM dexamethasone (
11015
,
Cayman Chemical Company
, Ann Arbor, MI). 293
T cells
and rhabdosarcoma cells were cultured in DMEM-HG
(16)
Irilone, a Red Clover Isoflavone, Combined with Progesterone Enhances PR Signaling through the Estrogen and Glucocorticoid Receptors
Journal of Natural Products
December 24, 2021
Julia R. Austin, Kailiang Li, Rocío Rivera Rivera Rodríguez, Daniel D. Lantvit, Brian T. Murphy, Joanna E. Burdette
Cayman Chemical
), 4-OH-
Tamoxifen
(
17308
,
Cayman Chemical
),
MG132
(M7449,
Sigma Aldrich
), dexamethasone (
11015
,
Cayman Chemical
), RU486 (
10006317
,
Cayman Chemical
), and irilone (BCN8188, Biocrick, 99% purity; Amb2264670,
(17)
Comprehensive targeting of resistance to inhibition of RTK signaling pathways by using glucocorticoids
Nature communications
December 1, 2021
Gong K, Guo G, Beckley NA, Yang X, Zhang Y, Gerber DE, Minna JD, Burma S, Zhao D, Akbay EA,
et al
.
(
10483
),
Afatinib
(
11492
), Osimertinib (
16237
),
Thalidomide
(
14610
),
Prednisolone
(
20866
),
Dexamethasone
(
11015
) were obtained from
Cayman Chemical
. For the in vivo experiments,
Prednisone
(
20677
) and
Thalidomide
(18)
SEC23A rescues SEC23B-deficient congenital dyserythropoietic anemia type II
Science advances
November 26, 2021
King R, Lin Z, Balbin-Cuesta G, Myers G, Friedman A, Zhu G, McGee B, Saunders TL, Kurita R, Nakamura Y,
et al
.
stem cell
factor (rhSCF, 50 ng/ml) (R&D, catalog #255-SC-01M), 1 μM dexamethasone (
Cayman
, catalog #
11015
), doxycycline (2 μg/ml;
Sigma-Aldrich
, catalog #D9891), Epogen (3 U/ml; Amgen), and penicillin-streptomycin
(19)
Selective Targeting of Class I Histone Deacetylases in a Model of Human Osteosarcoma
Cancers
August 20, 2021
Torres HM, VanCleave AM, Vollmer M, Callahan DL, Smithback A, Conn JM, Rodezno-Antunes T, Gao Z, Cao Y, Afeworki Y,
et al
.
ascorbic acid (Cayman Chemical, Ann Arbor, MI, USA,
16457
), 100 nM dexamethasone (
Cayman Chemical
,
11015
), and 10 mM β-glycerophosphate (BGP) (
Cayman Chemical
,
14405
). The
assay
was performed over 14 days,
(20)
Chromatin accessibility profiling identifies evolutionary conserved loci in activated human satellite cells
Stem Cell Research
August 11, 2021
Lisa S. Chow, Darko Bosnakovski, Douglas G. Mashek, Michael Kyba, Rita C. R. Perlingeiro, Alessandro Magli
and Recombinant Proteins",
Human
Fc-block,
Miltenyi Biotec
,
130-059-901
Dexamethasone
,
Cayman Chemical
,
11015
basic-FGF,
Peprotech
,
100-18B
-250mg Chick embryonic extract,US Biologies,C3999 Tn5 transposase+modified
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Dexamethasone from Cayman Chemical
Supplier Page
View Company Product Page
$65.00
Product Specs
Company Info
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