A23187 from Cayman Chemical

Product Specs
ItemA23187
CompanyCayman Chemical
Price $43.00Supplier Page View Company Product Page
Catalog Number11016
Quantity1 mg
Research AreaApoptosis, Cell Biology, Cell Death, Immunology & Inflammation, Innate Immunity, NETosis
FormatA crystalline solid
Molecular Weight523.6
Purity≥98%
Source/Expression SystemBacterium/Streptomyces chartreusis
OriginISR
FormulaC29H37N3O6
Storage-20

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Role of Rubicon in platelets: a promoter of thrombosis but not an autophagy repressorBlood AdvancesFebruary 24, 2026Hammodah R. Alfar, Elizabeth R. Driehaus, Alexis N. Smith, Daniëlle Marije Coenen, Dlovan F. D. D Mahmood, Jeremy P. Wood, Sidney W. Whiteheartcatalog no. 564631) and either collagen (20 μg/mL) or A23187 (10μM/mL; Cayman Chemical, catalog no. 11016). The thrombin generation reaction was initiated by adding a mixture of calcium and fluorogenic thrombin

(2) Non-cell-autonomous tumor promotion in DICER1 cancer predispositionDevelopmental CellJanuary 14, 2026Randolph K. Larsen, Jason A. Hanna, Hongjian Jin, Kristin B. Reed, Darden W. Kimbrough, Kyna Vuong, Jongchan Hwang, Grace E. Adkins, Jack D. Hopkins, Bradley T. Stevens, et al.,GE Healthcare,17-1440-02 Phorbol 12-myristate 13 acetate (PMA),Tocris,Cat #1201 A23187,Cayman Chemical,Cat #11016 pHrodo E. coli BioParticles conjugate for phagocytosis,Invitrogen,Cat #P35361 Disulfiram (Tetraethylthiuram

(3) Immune cell activation produces locally scrambled foci of plasma membrane lipidsFaraday DiscussionsAugust 13, 2025Daryna Sputay, Milka Doktorova, Sze Ham Chan, Emma Han Guo, Hong-Yin Wang, Joseph H. Lorent, Ilya Levental, Kandice R. Levental(STS) (S6942, Sigma-Aldrich) for 4 hours at 37 °C. Calcium ionophores A23187 (Cayman Chemical Company, 11016) and ionomycin (Thermo Scientific, J60628) were used to elevate intracellular [Ca2+] and induce PM scrambling

(4) Cell membranes sustain phospholipid imbalance via cholesterol asymmetryCellMay 15, 2025Milka Doktorova, Jessica L. Symons, Xiaoxuan Zhang, Hong-Yin Wang, Jan Schlegel, Joseph H. Lorent, Frederick A. Heberle, Erdinc Sezgin, Edward Lyman, Kandice R. Levental, et al.within 20 minutes. To determine the Di4 lifetime of scrambled plasma membranes, 3 mM A23187 (Cayman, #11016) was added to cells in the same CaR buffer for 15 minutes at 37°C. Following this treatment, the cells

(5) Cell membranes sustain phospholipid imbalance via cholesterol asymmetrybioRxivDecember 12, 2024Milka Doktorova, Jessica L. Symons, Xiaoxuan Zhang, Hong-Yin Wang, Jan Schlegel, Joseph H. Lorent, Frederick A. Heberle, Erdinc Sezgin, Edward Lyman, Kandice R. Levental, et al.CaCl2, pH 7.4, with 100x diluted Annexin V AF647 from ThermoFisher, #A23204). Ionophore A23187 (Cayman, #11016) diluted in Annexin V buffer was added to the cells with a final concentration of 6 μM. Cells were imaged

(6) Calcimycin Inhibits Cryptococcus neoformans In Vitro and In Vivo by Targeting the Prp8 Intein SplicingACS Infectious DiseasesSeptember 9, 2022Anil Mathew Tharappel, Zhong Li, Yan Chun Zhu, Xiangmeng Wu, Sudha Chaturvedi, Qing-Yu Zhang, Hongmin Liwith a novel mechanism of action. METHODS Chemicals and Reagents. Calcimycin (Cayman Chemical, 11016) (Figure S4, S5); SD broth (BD, 238230); Dulbecco’s modified Eagle’s medium (DMEM)-high glucose (Sigma,

(7) Myoblast deactivation within engineered human skeletal muscle creates a transcriptionally heterogeneous population of quiescent satellite-like cellsBiomaterialsMay 1, 2022Jason Wang, Torie Broer, Taylor Chavez, Chris J. Zhou, Sabrina Tran, Yu Xiang, Alastair Khodabukus, Yarui Diao, Nenad Bursacfor 6 h, latoxan: L8102), notexin (1 μg/ml for 6 h, latoxan: L8104), or A23187 (80μM for 1 h, Cayman: 11016). 4.8. RNA extraction and quantitative RT-PCR RNA was isolated using RNeasy Plus Micro Kit (Qiagen),

(8) Mycobacterium avium-intracellulare complex promote release of pro-inflammatory enzymes matrix metalloproteinases by inducing neutrophil extracellular trap formationScientific reportsApril 11, 2022Nakamura K, Nakayama H, Sasaki S, Takahashi K, Iwabuchi K.MA, USA); antibody to human β-actin antibody was from Sigma-Aldrich (St. Louis, MO, USA), and A23187 (11016) and GSK484 (17488) were from Cayman (Ann Arbor, MI, USA). Isolation of human neutrophils Ethical

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A23187 from Cayman Chemical

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Cayman Chemical

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A23187 from Cayman Chemical

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