Welcome Guest
Sign In
Register
Products
Popular Categories
Antibody Search
ELISA Kit Search
Biomolecules
Flow Cytometers
Thermal Cyclers
Microscopes
Transfection Reagents
Featured Products
New Products
Research Areas
ELISA
Western Blot
3D Cell Culture
Digital PCR
Quantitative PCR
Cell and Gene Therapy
In Vivo Models
Resources
eBooks
Bench Tips
Tech Insights
Editorial Articles
News
Product Reviews
Future Lab
White Papers
Infographics
Events
Promotions
Multimedia
Biocompare Webinars
Technologies Transforming Precision Medicine
Immunotherapy
Reproducibility
Transformative Technologies
Podcasts
Bench Tip Videos
All Videos and Webinars
Life Science Webinars
Write a Review
Antibodies
Kits/Reagents
Equipment
Services
Register
Sign In
Biocompare
Products
Protein Biochemistry
Chemicals and Reagents
TPPU
TPPU from Cayman Chemical
Be the first to write a review!
Citations:
(6)
Supplier Page
Supplier Page from
Cayman Chemical for
TPPU
Request Info
Description
A potent inhibitor of both human and mouse soluble epoxide hydrolase (IC50 = 3.7 and 2.8 nM, respectively); has superior pharmacokinetics compared to the 1-adamantylurea based inhibitors, like AUDA
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
TPPU
Company
Cayman Chemical
Price
$36.00
Supplier Page
View Company Product Page
Catalog Number
11120
Quantity
1 mg
Research Area
Cardiovascular Diseases, Cardiovascular System, Hypertension, Neuroprotection, Neuroscience
Format
A crystalline solid
Molecular Weight
359.3
Purity
≥98%
Storage
-20
Formula
C16H20F3N3O3
Origin
USA
Add to Compare List
Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (6)
(1)
Soluble epoxide hydrolase maintains steady-state lipid turnover linked with autocrine signaling in peritoneal macrophages
iScience
August 18, 2023
Feng Liu, Xueying Diao, Haolun Cong, Eriko Suzuki, Keiji Hasumi, Hiroshi Takeshima
(C-EH
inhibitor
),
Cayman Chemical
,
10007927
; CAS: 479413-70-2
TPPU
(C-EH
inhibitor
),
Cayman Chemical
,
11120
; CAS: 1222780-33-7 3-amino-4-hydroxy benzoic acid (N-phos
inhibitor
),"Tokyo Chemical Industry Co.,
(2)
Role of omega-3 endocannabinoids in the modulation of T-cell activity in a multiple sclerosis experimental autoimmune encephalomyelitis (EAE) model
The Journal of biological chemistry
February 1, 2023
Kim JS, Soto-Diaz K, Bingham TW, Steelman AJ, Das A.
N-[1-(1-oxopropyl)-4-piperidinyl]-N’-[4-(trifluoromethoxy)phenyl)-urea (10 μM;
Cayman Chemical
; catalog no.:
11120
) and PMSF (1 mM; Gold Bio; catalog no.: P-470) were utilized in a
1:20
tissue mass (g):volume (ml) ratio.
(3)
Deletion of soluble epoxide hydrolase suppressed chronic kidney disease-related vascular calcification by restoring Sirtuin 3 expression
Cell Death & Disease
November 1, 2021
Wanbing He, Jieping Huang, Yang Liu, Changming Xie, Kun Zhang, Xinhong Zhu, Jie Chen, Hui Huang
The culture medium was changed every 2 days. Treatments with t-AUCB (
Cayman
,
16568
) and
TPPU
(
Cayman
,
11120
) were used to
inhibit
the epoxide hydrolase of sEH. The
11,12-EET
(
Cayman
,
50511
) was used to increase
(4)
Inhibition of soluble epoxide hydrolase alleviates insulin resistance and hypertension via downregulation of SGLT2 in the mouse kidney
The Journal of biological chemistry
January 1, 2021
Luo J, Hu S, Fu M, Luo L, Li Y, Li W, Cai Y, Dong R, Yang Y, Tu L,
et al
.
IgG (H + L) (
AS003
; dilution
1:10,000
for WB
) were also purchased from
ABclonal Technology
.
TPPU
(no.
11120
),
5,6-EET
(no.
50211
),
8,9-EET
(no.
50351
),
11,12-EET
(no.
50511
),
14,15-EET
(no.
50651
), and
Soluble Epoxide Hydrolase Inhibitor Screening Assay Kit
(5)
14,15-Epoxyeicosatrienoic Acid Alleviates Pathology in a Mouse Model of Alzheimer's Disease
The Journal of neuroscience : the official journal of the Society for Neuroscience
October 14, 2020
Chen W, Wang M, Zhu M, Xiong W, Qin X, Zhu X.
coverslips and incubated with 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin4-yl) urea (
TPPU
; catalog #
11120
,
Cayman Chemical
) or 14,15-EET. Cells were harvested at 0, 5, 15, 30, 60, and 120 min after
TPPU
or
14,15-EET
(6)
Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea (TPPU): Resulting drug levels and modulation of oxylipin pattern
Prostaglandins & other lipid mediators
September 1, 2015
Ostermann AI, Herbers J, Willenberg I, Chen R, Hwang SH, Greite R, Morisseau C, Gueler F, Hammock BD, Schebb NH.
TPPU, 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (Fig. 1D, Sigma # SML0750,
Cayman
#
11120
) was synthesized in house as previously described17.
HPLC
grade acetonitrile (ACN), acetic acid (AcOH),
<<
<
>
>>
Reviews
Be the First to Write a Review!
TPPU from Cayman Chemical
Supplier Page
View Company Product Page
$36.00
Product Specs
Company Info
Citations
Reviews
Back To Top