(E)-Guggulsterone from Cayman Chemical

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Cayman Chemical for
(E)-Guggulsterone

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Description

A competitive antagonist of FXR (IC50 = 15 µM ) that inhibits chenodeoxycholic acid (CDCA)-induced transactivation of FXR; lowers LDL cholesterol and triglyceride levels in rodents fed a high cholesterol diet