Description
A tyrphostin compound that inhibits nerve growth factor (NGF)-dependent TrkA tyrosine phosphorylation in PC-12 cells (IC50 = ~40µM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 µM), and the VEGF receptor FLK1 (IC50 = ~1 µM)