Description
A protease inhibitor with diverse biological activities; inhibits calpain and the cysteine proteases cathepsins F, -K, -B, -H, and -L; induces cell cycle arrest at the G2/M phase in A431 human epidermoid carcinoma cells from 20-200 µM; inhibits protease-resistant prion protein accumulation in scrapie-infected neuroblastoma cells (IC50 = 0.5 µM); inhibits SARS-CoV and SARS-CoV-2 spike glycoprotein incorporation into pseudotyped VSV particles in Vero cells