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Protein Biochemistry
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PP2
PP2 from Cayman Chemical
Be the first to write a review!
Citations:
(9)
Supplier Page
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Cayman Chemical for
PP2
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Description
A potent, reversible, ATP-competitive, and selective inhibitor of the Src family of protein tyrosine kinases: p56lck (IC50 = 4 nM), p59fynT (IC50 = 5 nM), Hck (IC50 = 5 nM)
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
PP2
Company
Cayman Chemical
Price
$209.00
Supplier Page
View Company Product Page
Catalog Number
13198
Quantity
25 mg
Research Area
Cell Biology, Cell Signaling
Format
A crystalline solid
Molecular Weight
301.8
Purity
≥95%
Storage
-20
Formula
C15H16ClN5
Origin
USA
Type
Inhibitors
Specifications/Features
Amount:
25 mg
Additional Product Information
Synonym:
AGL 1879
Add to Compare List
Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (9)
(1)
TSP-1-CD47-integrin α4β1 axis drives T cell infiltration and synovial inflammation in rheumatoid arthritis
Front Immunol
April 16, 2025
Jialiang Hu, Xinmin Wang, Chuang Ge, Weiyan Qi, Zeqing Li, Yaoyao Wang, Wenting Lai, Wei Ji, Hanmei Xu
(Wuhan China). PKAI (476485) and PTX (516560) were from
Merck&Millipore
(Burlington, MA, USA).
PP2
(
13198
) was from
Cayman
(Ann Arbor, MI, USA). Human Thrombospondin-1 (SRP4805) was from Sigma-Aldrich (St.
(2)
Podosome Nucleation Is Facilitated by Multivalent Interactions between Syk and ITAM-containing Membrane Complexes
Journal of immunology (Baltimore, Md. : 1950)
October 1, 2024
Ghasempour S, Muise AM, Freeman SA.
(
Cayman Chemical
, Cat#
17665
),
Calmidazolium chloride
(
Tocris
, Cat#
2561
) and
PP2
(
Cayman Chemicals
, Cat#
13198
).
Western blotting
Cells seeded in 6-well plates were lysed with
RIPA buffer
(
Sigma Aldrich
, Cat#
R0278
)
(3)
Na/K-ATPase suppresses LPS-induced pro-inflammatory signaling through Lyn
iScience
September 16, 2022
Zhang J, Chang J, Beg MA, Huang W, Zhao Y, Dai W, Wu X, Cui W, Pillai SS, Lakhani HV,
et al
.
proteins" ,, Lipopolysaccharides from Escherichia coli O 55:B5,
Sigma-Aldrich
,Cat#L2880; EC: 297-473-0
PP2
,
Cayman chemical
,Cat#
13198
; CAS: 172889-27-9 N-acetylcysteine,
Cayman chemical
,Cat#
20261
; CAS: 616-91-1
Apocynin
,
Cayman chemical
,Cat#
11976
;
(4)
Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking
bioRxiv
June 3, 2022
Marion Schuller et al.
Diaveridine
(
Cayman Chemical
,
29427
),
N6-Benzyladenine
(
Cayman Chemical
,
21711
),
PP2
(
Cayman Chemical
,
13198
),
Temozolomide
(
Cayman Chemical
,
14163
),
Chrysophanol
(
Cayman Chemical
,
19870
),
Isoxanthopterin
(
Cayman Chemical
(5)
Phosphorylation of Na+,K+-ATPase at Tyr10 of the α1-Subunit is Suppressed by AMPK and Enhanced by Ouabain in Cultured Kidney Cells
The Journal of Membrane Biology
December 1, 2021
Metka Petrič, Anja Vidović, Klemen Dolinar, Katarina Miš, Alexander V. Chibalin, Sergej Pirkmajer
Src kinases 3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (
PP2
; No.
13198
,
Cayman Chemical
),
inhibitor
of ATP synthase oligomycin (No. 495455, Merck), insulin (Actrapid, NovoNordisk),
(6)
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking
Science Advances
April 16, 2021
Marion Schuller et al.
diaveridine (
Cayman Chemical
,
29427
),
N6-benzyladenine
(
Cayman Chemical
,
21711
),
PP2
(
Cayman Chemical
,
13198
), temozolomide (
Cayman Chemical
,
14163
), chrysophanol (
Cayman Chemical
,
19870
), and isoxanthopterin
(7)
HER2 decreases drug sensitivity of ovarian cancer cells via inducing stem cell-like property in an NFκB-dependent way
Bioscience Reports
March 29, 2019
Wenxiang Wang, Yuxia Gao, Jing Hai, Jing Yang, Shufeng Duan
(Cat. #481408) were purchased from Calbiochem (CA, U.S.A.). PD0325901 (Cat. #
13034
) and
PP2
(Cat. #
13198
) were purchased from
Cayman Chemical Company
(MI, U.S.A.).
Lapatinib
(Cat. #
S1028
) was purchased from
(8)
Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions
Developmental Cell
February 5, 2018
Pragati Pandey et al.
used at 500 nM)",
Sigma
,Cat#
B6292
Bis II (5 μM),
Sigma
,Cat# B3056
PP2
(10 μM),
Cayman Chemical
,Cat#
13198
(±)-Blebbistatin (50 μM),Calbiochem,Cat# 203390 Verapamil (10 μM),SCBT,Cat# sc-3590A
(9)
The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling
Scientific Reports
April 1, 2017
Ahmad Merhi, Paul Delrée, Anna Maria Marini
#
9901
) and
Bapta-AM
(
Selleckchem
, #
S7534
) were used at a 50 μM concentration.
PP2
(
Cayman Chemical
, #
13198
–1),
U0126
(
Cell signaling
, #
9903
),
PF-573228
(
Sigma
, #
PZ0117
), Gefitinib (Invivogen, #tlrl-gef) were
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PP2 from Cayman Chemical
Supplier Page
View Company Product Page
$209.00
Product Specs
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