Paraformaldehyde solution 4% in PBS from Santa Cruz Biotechnology, Inc.

Product Specs
ItemParaformaldehyde solution 4% in PBS
CompanySanta Cruz Biotechnology, Inc.
Price $63.00Supplier Page View Company Product Page
Catalog Numbersc-281692
Quantity1 L
TypeSample Preservatives

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Acute in vivo proximity labeling for membrane targeted proteomics in neuronal circuitsbioRxivJuly 16, 2026Maribel Anguiano, Run Zhang, Melanie Robles, Kaden P. Adams, Michelle R. Salemi, Brett S. Phinney, Christopher S. Leung, Ethan M. Fenton, Kuldeep Giri, Elinor Lewis, et al.(D8537–500ML, Sigma-Aldrich). Neurons were subsequently fixed with 4% (v/v) paraformaldehyde (PFA; sc-281692, Santa Cruz Biotechnology) in DPBS at room temperature for 10 min followed by two washes with DPBS.

(2) Brown fat protects against hepatic oxidative stress by remodeling the circulating metabolomeCell MetabJuly 14, 2026Dandan Wang, Mark Li, Tian Lu, Mami Matsushita, Juro Sakai, Masayuki Saito, Takeshi Yoneshiro, Shingo KajimuraE4378 EDTA,Sigma-Aldrich,Cat# E5134 DTT,Sigma-Aldrich,Cat# 43816 Paraformaldehyde,Santa Cruz Biotechnology,Cat# SC281692 PBS,Gibco,Cat# 10010023 Chloroform,Sigma-Aldrich,Cat# 650498 Acetonitrile,Thermo Fisher Scientific,Cat#

(3) Maturation is required to model ischemia-reperfusion injury in engineered human cardiac tissuesFront Bioeng BiotechnolJuly 13, 2026Trevor R. Nash, Roberta I. Lock, Vanessa Yi Ran Li, Morgan J. Lamberti, Youngbin Kim, Eloy Sanchez, Sharon Fleischer, Daniel Naveed Tavakol, Gordana Vunjak-Novakovicand staining. Tissues were fixed with 4% Paraformaldehyde Solution in PBS (Santa Cruz Biotechnology, sc-281692) for 20 min at room temperature, permeabilized in 0.25% Triton X-100 (Sigma, X100-100 mL) for 20 min

(4) Krüppel-like Factor 2 (KLF2) Regulates Autophagy, Mitophagy, Mitochondrial Health, and Function During Foam Cell FormationDiseases & ResearchJuly 3, 2026Sariful Islam Howlader Md, Department of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas 79106, USA, Das Manjusri, Hansda Surajit, Naidu Prathyusha, Das HiranmoyLow-Density Lipoprotein (ox-LDL, #L34357), both from Thermo Fisher Scientific. Paraformaldehyde (4%, #sc-281692) was purchased from Santa Cruz Biotechnology, while Triton X-100 (#T8787), RIPA lysis buffer (#20–188),

(5) Vitrification-warming delays preimplantation development and impairs mitochondrial function and cytoplasmic lattices integrity in mouse embryosiScienceJune 19, 2026Mariana T. Barroso, Jose A. Rodriguez Muñoz, Viola Sjöström, Konstantina Dindini, Jian Zhao, Kenny A. Rodriguez-Wallberg, Arturo Reyes Reyes PalomaresAntifade Mounting Medium with DAPI,Vector Laboratories,Cat# H-1200-10 Paraformaldehyde 4%,Santa Cruz,Cat# sc-281692 EmbryoMax Advanced KSOM Medium,Sigma-Aldrich,Cat# MR-101-D OVOIL,Vitrolife,Cat# 10029 ,, Experimental models

(6) Modeling Inherited Methylmalonic Acidemia Using Isogenic Human Induced Pluripotent Stem Cell-Derived Hepatocytes with Mutations in Methylmalonyl-CoA MutaseMicroPubl BiolJune 17, 2026Behshad Pournasr, Stephen Duncanwere differentiated, washed once with PBS, and fixed with 4% paraformaldehyde (w/v; Santa Cruz, TX, #sc-281692) for 20 minutes. After washing the samples three times with PBS, they were permeabilized using 0.4%

(7) Synaptophysin autoantibodies mediate synaptic dysfunction in cerebellar ataxiaCell Reports MedicineJune 16, 2026Samantha Ho, Hoi Kiu Wong, Dorina Shqau, Stephan Winklmeier, Marcus Grobe-Einsler, Kevin Rostasy, Tania Kümpfel, Franziska S. Thaler, Lior Brimberg, Marc A. Schneider, et al.[67-63-0]",Merck,1.09634.2511 "4′,6-diamidino-2-phenylindole (DAPI)",Thermo Fisher,62248 4% paraformaldehyde (PFA),Santa Cruz Biotechnology,sc-281692 B27,ThermoFisher,17504044 BDNF,R&D,248-BDB-005 Borate buffer (20×),ThermoFisher,28341 Bovine serum albumin (BSA

(8) MARBL: A Live-Cell Method for Profiling Bioenergetic Heterogeneity by Noncanonical Methionine Labeling of the Cell Surface ProteomebioRxivJune 2, 2026Lillian R. Delacruz, Ming Ye, Kendra A. Libby, Keran Han, Chad J. Munger, Yunping Qiu, Irwin J. Kurland, Alison E. Ringelminutes at 4°C. Finally, cells were fixed in 4% paraformaldehyde (Santa Cruz Biotechnology, Catalog No.: sc-281692) for 15 minutes at room temperature or overnight at 4°C and resuspended in either 1% BSA (w/v) in 1X

(9) Programming Degradation and Drug Release Through Micropatterning of PLGA FilmsACS Appl Mater InterfacesMay 27, 2026Irene Guerriero, Cristiano Pesce, Raffaele Spanò, Stefania Sganga, Nicola Tirelli, Anna Lisa Palange, Daniele Di Mascolo, Paolo Decuzzipurchased from Thermo Fisher Scientific (Segrate, Italy). Paraformaldehyde solution 4% in PBS (product code sc-281692) was from Santa Cruz Biotechnology Inc. (Heidelberg, DE). Surgipath FSC 22 Frozen Section Compound was

(10) NFAT5: A Metabolic Time Capsule Encoding the History of Paternal Metabolic Oxidative Stress Within the Male Reproductive TractAntioxidants (Basel)May 20, 2026Nicola Mosca, Antonella Migliaccio, Teresa Chioccarelli, Donato Cappetta, Antonella De Angelis, Marialucia Telesca, Liberato Berrino, Danila Valletta, Alice Luddi, Chiara Donati, et al.= 6 animals for each experimental condition) were dried on slides and fixed in 4% paraformaldehyde (sc-281692; Santa Cruz Biotechnology, Heidelberg, Germany) for 20 min at ambient temperature (RT). For acrosome

(11) IND-enabling safety and efficacy of RPESC-RPE-4W, an adult RPE progenitor cell therapy for dry age-related macular degenerationCell Rep MedMay 19, 2026Brigitte L. Arduini, Timothy A. Blenkinsop, Michael Naimark, Susan Borden, Carol Charniga, Melissa Campbell, Natasha Rugenstein, Richard J. Davis, Nazia Alam, Glen Prusky, et al.CAS-Block Histochemical Reagent,Thermo Fisher Scientific,00–8120 Paraformaldehyde solution 4% in PBS,Santa Cruz Biotechnology,sc-281692 Triton X-100,Sigma,T9284-100ML TGF-beta recombinant protein,Peprotech,100-21C TNF-alpha recombinant

(12) The basic domain of Suv39h2 buffers mitoxantrone-induced heterochromatin destabilizationiScienceMay 15, 2026Kalina M. Świst-Rosowska, Reagan W. Ching, Birgit Koschorz, Carmen Galan, Bettina Engist, Thomas Jenuwein89900 cOmplete EDTA-free protease inhibitors,Roche,Cat#: 11873580001 paraformaldehyde,Santa Cruz,Cat#: sc-281692 triton X-100,Sigma-Aldrich,Cat#: X100 VECTASHIELD Antifade Mounting Medium with DAPI,Vector Leboratories,Cat#:

(13) IL-1–mediated vitreous inflammation as an early indicator of retinal ganglion cell loss following acute optic nerve injuryJournal of NeuroinflammationMay 14, 2026Shichu Chang, Weijia Fan, Jiahui Wu, Lei Xu, Virginia A. Lee, Charlotte Zhang, Edward P. Kronenberg, Wenjin Xu, Hu Yang, Hao F. Zhang, et al.France) and perfused with phosphate-buffered saline (PBS) and then 4% paraformaldehyde (PFA, ChemCruz, sc281692; Santa Cruz Biotechnology, Dallas, TX, USA). After perfusion, the eyes were enucleated. For whole-eye

(14) Macrophages orchestrate antiviral defense and epithelial repair in a human iPSC-derived alveolar air-liquid interfaceJCI InsightMay 8, 2026Declan L. Turner, Hannah Baric, Katelyn Patatsos, Sahel Amoozadeh, Michael See, Kathleen A. Strumila, Jack T. Murphy, Jeremy J. Wiyana, Liam Gubbels, Elizabeth S. Ng, et al.imaging, and transmission electron microscopy. Samples were fixed with 4% PFA (Santa Cruz Biotechnology, sc281692) for 20 minutes at room temperature and stored at 4°C prior to staining. ALI membranes were excised

(15) Lipid Transfer Proteins and PI4KIIα Initiate Nuclear p53-Phosphoinositide SignalingJournal of Biological ChemistryMay 8, 2026Noah D. Carrillo, Mo Chen, Poorwa Awasthi, Tianmu Wen, Xue Yang, Colin Sterling, Dhruv Brahmbhatt, Vincent L. Cryns, Richard A. Andersoncoated with 0.2% gelatin (#G9391, Millipore Sigma). Cells were fixed with 4% paraformaldehyde (PFA) (#sc-281692, Santa Cruz Biotechnology) for 20 min at room temperature, then washed three times with PBS. Next, the

(16) EMMIs: Engineered Myometrial Microtissues for Direct Quantification of Oxytocin-Induced ContractilitybioRxivMay 5, 2026Karla I Ortega Sandoval, Ritu M Dave, Cailin R Gonyea, Kaci Mitchum, Alana Aristimuno Millan, Shriya Suryakumar, Antonina I. Frolova, Shreya A RaghavanDow Corning (Midland, MI). Paraformaldehyde (4%) was purchased from Santa Cruz Biotechnology (Cat# sc-281692). Bovine serum albumin (BSA) was purchased from Fisher Bioreagents (Cat# BP9706-100). Anti-connexin-43

(17) Long-term consequences of prenatal saccharin exposure: evidence of sex-specific molecular programing in the prefrontal cortex and behavior of adolescent ratsFrontiers in Behavioral NeuroscienceApril 30, 2026Beatriz Pacheco-Sánchez, Raquel López-Merchán, Pablo Rubio, Pilar García-Martos, Juan Suárez, Carlos Sanjuan, Leticia Rubio, Stella Martín-de-Las-Heras, Fernando Rodríguez de Fonseca, Francisco Alén, et al.tests (n = 8 for each group) were extracted and fixed in a solution of paraformaldehyde 4% (Santa Cruz, SC-281692) and then stored at -20. Then, they were cut into coronal sections of 30 micrometers using a vibratome;

(18) Space-time acoustofluidic tweezers for dynamic and selective manipulation of microparticlesSci AdvApril 29, 2026Qian Wu, Zhiteng Ma, Kaichun Yang, Haojun Xu, John D. H. Mai, Ty Naquin, Mingyuan Liu, Ying Chen, Joseph Rufo, Jingtong Ma, et al.without acoustic vibration. After 10 days, colonies were fixed with 4% paraformaldehyde (Santa Cruz, sc-281692), stained with crystal violet (Sigma-Aldrich, 94448-250ML-F), and imaged by microscopy. Cell migration assay

(19) Human iPSC-derived macrophages for studying intrinsic and extrinsic factors in cystic fibrosisEXOApril 27, 2026Daniel Naveed Tavakol, Pamela L. Graney, Meghan R. Pinezich, Connie Chen, Maria Samaritano, Derek Ning, Katherine M. Cunningham, Gordana Vunjak-Novakovicattachment, macrophages were fixed with 4% Paraformaldehyde Solution in PBS (Santa Cruz Biotechnology, Sc-281692) for 20 min at room temperature, permeabilized in 0.25% Triton X-100 (Sigma, X100–100mL) for 20 min

(20) KLF2 Promotes Ellagic Acid-Mediated Osteogenic Differentiation of Dental Pulp-Derived Stem Cells via Autophagy and Mitochondrial RegulationDiseases & ResearchApril 23, 2026Naidu Prathyusha, Department of Pharmaceutical Sciences, Jerry H. Hodge School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas 79106, USA, Sariful Islam Howlader Md, Hansda Surajit, Das Manjusri, Das HiranmoyNonfat dry milk (#M0841) was obtained from LabScientific (Highlands, NJ, USA), and paraformaldehyde (#sc-281692) was procured from Santa Cruz Biotechnology (Dallas, TX, USA). A molecular weight marker (#RPN800E)

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