Description
A CB2 receptor agonist; selective for the CB2 over the CB1 receptor (Kis = 658 and >10,000 nM, respectively); acts as an agonist at human, rat, and mouse CB2 receptors but shows greater activity at human CB2 (EC50 = 131 nM) than at rat and mouse CB2 receptors (EC50 = 785 and 2,000 nM, respectively); produces antinociception to thermal, but not mechanical, pain in rats