Chlorin e6 from Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

(1) Hypoxia modulates P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) drug transporters in brain endothelial cells of the developing human blood-brain barrierHeliyonMay 15, 2024Hafsah Mughis, Phetcharawan Lye, Guinever E. Imperio, Enrrico Bloise, Stephen G. Matthews[8,40,43]. Briefly, hfBECs were incubated with 2 μM chlorin e6 (Ce6, Santa Cruz Biotechnology, product #SC-263067; 37 °C, 5 % CO2, 1 h). Ce6 is a photosensitizer that was identified as a specific BCRP substrate [45,46].

(2) Three-in-one: exploration of co-encapsulation of cabazitaxel, bicalutamide and chlorin e6 in new mixed cyclodextrin-crosslinked polymers†RSC AdvancesApril 3, 2023Elisabetta Pancani, Daniele Veclani, Marco Agnes, Arianna Mazza, Alessandro Venturini, Milo Malanga, Ilse Manet(BIC, racemic mixture, purity 99.85%, CAS 90357-06-5) were purchased from MedChemExpress; chlorin e6 sc-263067 (purity > 95%, Santa Cruz Biotechnology, Inc.) was purchased from Santa Cruz Biotechnology, Inc. The

(3) Effects of bacterial and viral pathogen-associated molecular patterns (PAMPs) on multidrug resistance (MDR) transporters in brain endothelial cells of the developing human blood-brain barrierFluids and barriers of the CNSJanuary 31, 2023Lye P, Bloise E, Matthews SG.treated with bacterial and viral infection as described above. The BCRP substrate Chlorin e6 (Ce6; 2 uM; SC-263067, Santa Cruz Biotechnology) was pre-incubated with Tyrode salts’ solution (Sigma) in a 37 °C bead bath

(5) Functional Expression of Multidrug-Resistance (MDR) Transporters in Developing Human Fetal Brain Endothelial CellsCellsJuly 21, 2022Lye P, Bloise E, Imperio GE, Chitayat D, Matthews SG.adaptations. Briefly, hfBECs were seeded as described above. The BCRP substrate Chlorin e6 (Ce6; 2 uM; SC-263067, Santa Cruz Biotechnology) was pre-incubated with Tyrode salts’ solution (Sigma) in a 37 °C bead bath

(6) Fetal glucocorticoid exposure leads to sex-specific changes in drug-transporter function at the blood-brain barrier in juvenile guinea pigsFASEB journal : official publication of the Federation of American Societies for Experimental BiologyApril 1, 2022Eng ME, Bloise E, Matthews SG.CO2. For the BCRP assay, cells were incubated with 5 µM chlorin e6 (Ce6, Santa Cruz Biotechnology, #SC‐263067) for 1 h at 37°C and 5% CO2. After incubation, plates were placed on ice, and cells were washed twice

(8) Sonosensitizer-Functionalized Graphene Nanoribbons for Adhesion Blocking and Sonodynamic Ablation of Ovarian Cancer SpheroidsAdvanced healthcare materialsJuly 1, 2021Lee HR, Kim DW, Jones VO, Choi Y, Ferry VE, Geller MA, Azarin SM.a brief sonication. Synthesis and characterization of GNR-PEG-Ce6: Ce6 (Santa Cruz Biotechnology sc-263067) was dissolved in dimethyl sulfoxide (DMSO), followed by dilution in water to achieve the desired final

(9) Bacteria Single-Cell and Photosensitizer Interaction Revealed by Quantitative Phase ImagingInternational journal of molecular sciencesMay 11, 2021Buzalewicz I, Ulatowska-Jarża A, Kaczorowska A, Gąsior-Głogowska M, Podbielska H, Karwańska M, Wieliczko A, Matczuk AK, Kowal K, Kopaczyńska M.

(10) Function of Multidrug Resistance Transporters is Disrupted by Infection Mimics in Human Brain Endothelial CellsTissue barriersApril 3, 2021Eustaquio Do Imperio G, Lye P, Bloise E, Matthews SG.activity assay was adapted from a previous study16 using Chlorin 6 (Ce6, Santa Cruz Biotechnology, #SC-263067) as a specific BCRP substrate.17 Cells were incubated with 2 nM Ce6 (37°C; 5% CO2; 1 h). Plates were

(11) Folic acid-modified bovine serum albumin nanoparticles with doxorubicin and chlorin e6 for effective combinational chemo-photodynamic therapyMaterials science & engineering. C, Materials for biological applicationsDecember 1, 2020Lee H, Kim S, Oh C, Khan I, Shukla S, Bajpai VK, Han YK, Huh YS.

(15) Development of an ultrasound triggered nanomedicine-microbubble complex for chemo-photodynamic-gene therapyNanomedicine : nanotechnology, biology, and medicineJuly 1, 2020Jang Y, Kim D, Lee H, Jang H, Park S, Kim GE, Lee HJ, Kim HJ, Kim H.

(19) Combination of chemotherapy and photodynamic therapy for cancer treatment with sonoporation effectsJournal of controlled release : official journal of the Controlled Release SocietyAugust 10, 2018Lee H, Han J, Shin H, Han H, Na K, Kim H.

(20) Light-Guided Nanomotor Systems for Autonomous Photothermal Cancer TherapyACS applied materials & interfacesJanuary 24, 2018Choi H, Lee GH, Kim KS, Hahn SK.

Chlorin e6 Chemicals