CAY10614 from Cayman Chemical | Biocompare.com

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CAY10614

Description

An antagonist of lipid A activation of TLR4 (IC50 =1.68 µM), in a cell-based assay; significantly improves survival of mice given intraperitoneal LPS

Product Specs
ItemCAY10614
CompanyCayman Chemical
Price $61.00Supplier Page View Company Product Page
Catalog Number13615
Research AreaImmunology & Inflammation, Innate Immunity, Pattern Recognition, Sepsis/Shock
FormatA crystalline solid
Molecular Weight756
Purity≥98%
Storage-20
FormulaC42H78INO2
OriginUSA
TypeInhibitors
Quantity1 mg

Specifications/Features

Ki, IC, EC, or working concentration: IC50: 1.68 µM

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Cayman Chemical

Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Calcification Induced by Type I Interferon in Human Aortic Valve Interstitial Cells Is Larger in Males and Blunted by a Janus Kinase InhibitorArteriosclerosis, thrombosis, and vascular biologySeptember 1, 2018Parra-Izquierdo I, Castaños-Mollor I, López J, Gómez C, San Román JA, Sánchez Crespo M, García-Rodríguez C.inhibitor SN50 (Calbiochem, number 481480), TLR4 signaling antagonist CAY10614 (Cayman Chem, number 13615), and BMP (bone morphogenetic protein) antagonist noggin (Invitrogen, number PHC1506). Protein content

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