Description
A potent inhibitor of binding of an SDF-1 peptide mimic to CXCR4 (EC50 = 0.3 nM); prevents CXCR4/SDF-1-mediated modulation of cAMP (EC50 = 1.2 nM) in cells; blocks SDF-1-induced Matrigel™ invasion by MDA-MB-231 human breast adenocarcinoma cells (EC50 = 5.2 nM)