FIPI from Cayman Chemical

Product Specs
ItemFIPI
CompanyCayman Chemical
Price $143.00Supplier Page View Company Product Page
Catalog Number13563
Research AreaCell Biology, Cytoskeleton & Motor Proteins
FormatA crystalline solid
Molecular Weight421.5
Purity≥98%
Storage-20
FormulaC23H24FN5O2
OriginCHN
TypeInhibitors
Quantity5 mg

Specifications/Features

Ki, IC, EC, or working concentration: IC50: 25 nM for PLD1
IC50: 20 nM for PLD2

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Phosphatidylserine and RhoB connect PI4P and PA metabolism to maintain plasma membrane identityJournal of Cell BiologyAugust 3, 2026Shiying Huang, Yeun Ju Kim, Xiaofu Cao, Timothy W. Bumpus, Mira Sohn, Matthew Tyler Menold, Ryan K. Dale, Jin Joo Kang, Saori Uematsu, Shagun Gupta, et al.Phorbol-12-Myristate-13-Acetate, Santa Cruz Biotechnology (sc-3576, CAS #: 16561-29-8); FIPI, Cayman Chemical (13563, CAS #: 939055-18-2); JNK-IN-8, Ambeed Inc. (A206353, CAS #: 1410880-22-6); AZD6244, BioVision (2234–5,

(2) Inhibition of phospholipase D1 reduces pancreatic carcinogenesis in mice partly through a FAK-dependent mechanismCarcinogenesisJanuary 20, 2025Hala A. Addassi, Irena Krga, Fernando Villarreal, Joseph F. LaComb, Michael A. Frohman, Karen Matsukuma, Gerardo G. Mackenzieintraperitoneal injections, twice daily, for 35 days of either vehicle (a solution of 4% DMSO/96% PBS) or FIPI (Cat# 13563; Cayman Chemical Company, Ann Arbor, MI) at a dose of 3 mg/kg body weight in 4% DMSO/96% PBS followed

(3) A phosphorylation-controlled switch confers cell cycle-dependent protein relocalizationNature Cell BiologyOctober 1, 2024Xiaofu Cao, Shiying Huang, Mateusz M. Wagner, Yuan-Ting Cho, Din-Chi Chiu, Krista M. Wartchow, Artur Lazarian, Laura Beth McIntire, Marcus B. Smolka, Jeremy M. BaskinPhos-tag acrylamide, NARD (AAL-107); 5-gluoro-2-indolyl des-chlorohalopemide (FIPI), Cayman Chemical (13563, CAS#: 939055-18-2); 5-hexyn-1-ol, Sigma-Aldrich (302015, CAS#: 928-90-5); AZDye 647-Azide, Click Chemistry

(4) Imaging Interorganelle Phospholipid Transport by Extended Synaptotagmins Using Bioorthogonally Tagged LipidsACS Chemical BiologyAugust 16, 2024Lin Luan, Dongjun Liang, Din-Chi Chiu, Reika Tei, Jeremy M. Baskin(Cat # 13778150) were purchased from Thermo Fisher. FIPI was purchased from Cayman Chemical (Cat # 13563). Phorbol 12-myristate 13-acetate (PMA) was purchased from ChemCruz (Cat # SC-3576). MitoView 405 was

(5) Phosphatidic acid is an endogenous negative regulator of PIEZO2 channels and mechanical sensitivityNature CommunicationsAugust 15, 2024Matthew Gabrielle, Yevgen Yudin, Yujue Wang, Xiaoyang Su, Tibor Rohacsinhibition of PLDs, cells were incubated in DMEM/F-12 (HAM) containing 500 nM FIPI (Cayman Chemical, Cat. # 13563) or an equivalent volume of DMSO (0.005%) for 30 min and were patched in extracellular solution containing

(6) Mono- and Polyunsaturated Phosphatidic Acid Regulate Distinct Steps of Regulated Exocytosis in Neuroendocrine CellsSSRN Electronic JournalMarch 31, 2022Emeline Tanguy et al.ab290; RRID:AB_303395 Gold particle-conjugated anti-rabbit Aurion N/A FIPI Cayman Chemicals Cat# 13563 CAY10593 Cayman Chemicals Cat# 13206 CAY10594 Cayman Chemicals Cat# 13207 Lipofectamine 2000 Thermo Scientific

(7) Activity-based, bioorthogonal imaging of phospholipase D reveals spatiotemporal dynamics of GPCR-Gq signalingCell chemical biologyJanuary 20, 2022Liang D, Cheloha RW, Watanabe T, Gardella TJ, Baskin JM.HY-119706 D-luciferin,Gold Bio,Cat# L-123-250 Dyngo-4a,Selleck Chem,Cat# S7163 FIPI,Cayman Chemical,Cat# 13563 PLD1i,"Laboratory of Alex Brown, Vanderbilt University",VU0359595 PLD2i,"Laboratory of Alex Brown,

(8) Spatiotemporal control of phosphatidic acid signaling with optogenetic, engineered phospholipase DsThe Journal of cell biologyMarch 2, 2020Tei R, Baskin JM.VWR (catalog number 0486); 5-gluoro-2-indolyl des-chlorohalopemide, Cayman Chemical (catalog number 13563); DGK inhibitor I (R59022), Enzo Life Sciences (catalog number ALX-430-027); PMA, ChemCruz (catalog

(9) Targeting PKCδ as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung CancerCancer cellDecember 10, 2018Lee PC, Fang YF, Yamaguchi H, Wang WJ, Chen TC, Hong X, Ke B, Xia W, Wei Y, Zha Z, et al.,R & D Systems,2285 Sotrastaurin,Chemscene,SC-0090 U-73122,Cayman Chemical,70740 Edelfosine,R & D Systems,3022 FIPI,Cayman Chemical,13563 VU0359595,Sigma,SML0566 IWP2,Cayman Chemical,13951 IWP4,Cayman Chemical,13954 LGK-974,Xcess Biosciences,M60106 Gefitinib,LC

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Specifications/Features

Cayman Chemical

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FIPI from Cayman Chemical

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