Stat3 Inhibitor VI, S3I-201 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemStat3 Inhibitor VI, S3I-201
CompanySanta Cruz Biotechnology, Inc.
Price $148.00Supplier Page View Company Product Page
Catalog Numbersc-204304
Quantity10 mg
TypeBiochemical Reagents
Molecular Weight365.36

Specifications/Features

Storage:
501919-59-1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Targeting staphylococcal enterotoxin B binding to CD28 as a new strategy for dampening superantigen-mediated intestinal epithelial barrier dysfunctionsFront ImmunolMarch 6, 2024Carola Amormino, Emanuela Russo, Valentina Tedeschi, Maria Teresa Fiorillo, Alessandro Paiardini, Francesco Spallotta, Laura Rosanò, Loretta Tuosto, Martina Kunklwas > 95% pure and used in culture at 10 μM final concentration. PS1145 (#P6624, Merck) and S31-201 (#sc-204304, Santa Cruz Biotechnology) inhibitory drugs were used at 10 μM and 100 μm, respectively. Cytokine production:

(2) CXCL13 contributes to chronic pain of a mouse model of CRPS-I via CXCR5-mediated NF-κB activation and pro-inflammatory cytokine production in spinal cord dorsal hornJournal of neuroinflammationMay 8, 2023Wang J, Yin C, Pan Y, Yang Y, Li W, Ni H, Liu B, Nie H, Xu R, Wei H, et al.

(3) Combining TNFR2-Expressing Tregs and IL-6 as Superior Diagnostic Biomarkers for High-Grade Serous Ovarian Cancer MassesCancersJanuary 21, 2023Kampan NC, Kartikasari AER, Deceneux C, Madondo MT, McNally OM, Flanagan KL, Aziz NA, Stephens AN, Reynolds J, Quinn MA, et al.

(4) Integrative analysis of drug response and clinical outcome in acute myeloid leukemiaCancer cellAugust 8, 2022Bottomly D, Long N, Schultz AR, Kurtz SE, Tognon CE, Johnson K, Abel M, Agarwal A, Avaylon S, Benton E, et al.

(5) Inflammation-induced PELP1 expression promotes tumorigenesis by activating GM-CSF paracrine secretion in the tumor microenvironmentThe Journal of biological chemistryJanuary 1, 2022Vuttaradhi VK, Ezhil I, Ramani D, Kanumuri R, Raghavan S, Balasubramanian V, Saravanan R, Kanakarajan A, Joseph LD, Pitani RS, et al.protein (catalog no.: PMC2014) from Thermo Fisher Scientific, and STAT3 inhibitor S31-201 (catalog no.: sc-204304) from Santa Cruz Biotechnology were procured. Antibodies, plasmids, and siRNA Anti-PELP1 antibody

(6) Interaction between CD36 and FABP4 modulates adipocyte-induced fatty acid import and metabolism in breast cancerNPJ breast cancerSeptember 24, 2021Gyamfi J, Yeo JH, Kwon D, Min BS, Cha YJ, Koo JS, Jeong J, Lee J, Choi J.

(7) Podocyte-specific KLF4 is required to maintain parietal epithelial cell quiescence in the kidneyScience advancesSeptember 3, 2021Pace JA, Bronstein R, Guo Y, Yang Y, Estrada CC, Gujarati N, Salant DJ, Haley J, Bialkowska AB, Yang VW, et al.

(8) Cardiac Tissue Factor Regulates Inflammation, Hypertrophy, and Heart Failure in Mouse Model of Type 1 DiabetesDiabetesSeptember 1, 2021Cibi DM, Sandireddy R, Bogireddi H, Tee N, Ghani SABA, Singh BK, Mackman N, Singh MK, Singh A.

(9) TSLP-induced collagen type-I synthesis through STAT3 and PRMT1 is sensitive to calcitriol in human lung fibroblastsBiochimica et biophysica acta. Molecular cell researchSeptember 1, 2021Jin A, Tang X, Zhai W, Li Y, Sun Q, Liu L, Yang X, Ren H, Lu S.

(10) Integrin αVβ1 regulates procollagen I production through a non-canonical transforming growth factor β signaling pathway in human hepatic stellate cellsThe Biochemical journalMay 14, 2021Han Z, Ma Y, Cao G, Ma Z, Chen R, Cvijic ME, Cheng D.

(11) Targeting the IL-6/STAT3 Signalling Cascade to Reverse Tamoxifen Resistance in Estrogen Receptor Positive Breast CancerCancersMarch 25, 2021Tsoi H, Man EPS, Chau KM, Khoo US.Thermo Scientific, Waltham, MA, USA) were dissolved in double-distilled water. STAT3 Inhibitor VI S3I-201 (sc-204304; Santa Cruz Biotechnology, Dallas, TX, USA) was dissolved in DMSO. Tocilizumab (TCZ; Actemra®; Roche,

(12) miR-130a activates the VEGFR2/STAT3/HIF1α axis to potentiate the vasoregenerative capacity of endothelial colony-forming cells in hypoxiaMolecular therapy. Nucleic acidsMarch 5, 2021Guduric-Fuchs J, Pedrini E, Lechner J, Chambers SEJ, O''Neill CL, Mendes Lopes de Melo J, Pathak V, Church RH, McKeown S, Bojdo J, et al.

(13) STAT3 Is an Upstream Regulator of Granzyme G in the Maternal-To-Zygotic Transition of Mouse EmbryosInternational journal of molecular sciencesJanuary 5, 2021Ou-Yang H, Wu SC, Sung LY, Yang SH, Yang SH, Chong KY, Chen CM.exposed to inhibitors beginning at the zygote stage. The STAT3 inhibitors, 100-μM S3I201 (cat. no. sc-204304; Santa Cruz Biotech. Inc., Santa Cruz, CA, USA) [51] or 5-μM WP1066 (cat. no. ALX-270-483; Enzo Life Science

(14) Mistletoe Extract Targets the STAT3-FOXM1 Pathway to Induce Apoptosis and Inhibits Metastasis in Breast Cancer CellsThe American journal of Chinese medicineJanuary 1, 2021Kwon YS, Chun SY, Kim MK, Nan HY, Lee C, Kim S.

(15) STAT3 enhances radiation-induced tumor migration, invasion and stem-like properties of bladder cancerMolecular medicine reportsJanuary 1, 2021Wang F, Ma X, Mao G, Zhang X, Kong Z.

(16) BATF regulates innate lymphoid cell hematopoiesis and homeostasisScience immunologyDecember 4, 2020Liu Q, Kim MH, Friesen L, Kim CH.

(17) Concurrent Targeting of Potential Cancer Stem Cells Regulating Pathways Sensitizes Lung Adenocarcinoma to Standard ChemotherapyMolecular cancer therapeuticsOctober 1, 2020Shibata M, Ooki A, Inokawa Y, Sadhukhan P, Ugurlu MT, Izumchenko E, Munari E, Bogina G, Rudin CM, Gabrielson E, et al.(CDDP; Sigma-Aldrich, St Louis, MO, USA; #P4394), S3I-201 (Santa Cruz Biotechnology, Dallas, TX, USA; #sc-204304) (18), and verteporfin (MedKoo, Morrisville, NC, USA; #203120). Author Manuscript Recombinant interleukin-6

(18) Intermittent hypoxia mediated by TSP1 dependent on STAT3 induces cardiac fibroblast activation and cardiac fibrosiseLifeJanuary 14, 2020Bao Q, Zhang B, Suo Y, Liu C, Yang Q, Zhang K, Yuan M, Yuan M, Zhang Y, Li G.Kit,Promega Corporation,Cat# LS1040, "Chemical compound, drug",S3I-201,Santa Cruz Biotechnology,Cat# sc-204304, "Chemical compound, drug",TG101209,MedChem Express,Cat# HY-10410, "Software, algorithm",Prism version

(19) SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES CellsCellsJanuary 10, 2020Cai BH, Lee HY, Chou CK, Wu PH, Huang HC, Chao CC, Chung HY, Kannagi R.

(20) CD28 Autonomous Signaling Orchestrates IL-22 Expression and IL-22-Regulated Epithelial Barrier Functions in Human T LymphocytesFrontiers in immunologyJanuary 1, 2020Kunkl M, Amormino C, Frascolla S, Sambucci M, De Bardi M, Caristi S, Arcieri S, Battistini L, Tuosto L.(#130-093-931, 50 ng ml−1). The following inhibitory drugs were used: PS1145 (#P6624, Sigma Aldrich), S31-201 (#sc-204304, Santa Cruz Biotechnology), AS605240 (#A0233, Sigma Aldrich). CACO-2 Cell Stimulation and Western Blotting CACO-2 cells

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Stat3 Inhibitor VI, S3I-201 Chemicals

Stat3 Inhibitor VI, S3I-201 from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Stat3 Inhibitor VI, S3I-201 from Santa Cruz Biotechnology, Inc.

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