U-46619 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemU-46619
CompanySanta Cruz Biotechnology, Inc.
Price $240.00Supplier Page View Company Product Page
Catalog Numbersc-201242
Quantity1 mg
TypeBiochemical Reagents
Molecular Weight350.49

Specifications/Features

Storage:
56985-40-1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Novel insights into the regulation of NF2/SWH signaling in granulosa cells of prehierarchical follicle development in hen ovaryPoultry ScienceMarch 1, 2026Xue Sun, Ning Qin, Shengxiao Cao, Sheng Wang, Yuhan Sun, Yu Ou, Chunchi Yan, Chang Ma, Jinghua Zhao, Rifu Xu, et al.h to screen out the best processing time of SB203580 (S1863, Beyotime, Jiangsu, China) and U46619 (sc-201242, Santa Cruz, Dallas, TX, USA) as described previously (Qi, J et al., 2021, Liu, Y et.al, 2022, Li, X

(2) Dynamic three dimensional environment for efficient and large scale generation of smooth muscle cells from hiPSCsStem cell research & therapyDecember 3, 2024Green A, Wei Y, Warram JM, Hartman YE, Geng X, Nguyen T, Ye L, Zhang J.was replaced with fresh SMCG medium supplemented with 50 µM of the prostaglandin H2 analog U46619 (SC-201242, Santa Cruz Biotech.) for 30 min, and images were collected with an Olympus CKX53 microscope. Tube

(3) FOXA2 attenuates lipopolysaccharide‑induced pneumonia by inhibiting the inflammatory response, oxidative stress and apoptosis through blocking of p38/STAT3 signalingExperimental and therapeutic medicineOctober 1, 2023Xue Z, Li Y, Xiao S, Zhang H, Xu J.addition, to investigate the molecular mechanism, WI-38 cells were pretreated with U46619 (2 mM; cat. no. sc-201242; Santa Cruz Biotechnology, Inc.), an activator of p38 signaling (25), for 4 h at 37˚C prior to LPS exposure.

(4) Hydrogen Sulfide Regulates Glucose Uptake in Skeletal Muscles via S-Sulfhydration of AMPK in Muscle Fiber Type-Dependent WayThe Journal of nutritionOctober 1, 2023Li K, Wang M, Wang R, Wang X, Jiao H, Zhao J, Zhou Y, Li H, Lin H.

(5) EGFR-phosphorylated GDH1 harmonizes with RSK2 to drive CREB activation and tumor metastasis in EGFR-activated lung cancerCell reportsDecember 13, 2022Kang J, Chun J, Hwang JS, Pan C, Li J, Boese AC, Young I, Malin CM, Kang Y, Gibbons DL, et al.796,Selleckchem,Cat#S1574; CAS: 285983-48-4 "U-46619, P38 activator",Santa Cruz Biotechnology,Cat#sc-201242; CAS: 56985-40-1 Axitinib,Selleckchem,Cat#S1005; CAS: 319460-85-0 BMS-777607,Selleckchem,Cat#S1561;

(6) Discovery of 7, 4''-dimethoxy-3-hydroxyflavone as a protease-activated receptor 4 antagonist with antithrombotic activity and less bleeding tendency in miceBiochemical pharmacologyAugust 1, 2022Lin YT, Li Y, Hsu HC, Tsai JY, Lee JH, Tai CJ, Wu MJ, Wu CC.

(7) Effects of fasudil on blood-brain barrier integrityFluids and barriers of the CNSJune 3, 2022Sato K, Nakagawa S, Morofuji Y, Matsunaga Y, Fujimoto T, Watanabe D, Izumo T, Niwa M, Walter FR, Vigh JP, et al.

(8) 3,5,2'',4''-Tetramethoxystilbene, a fully methylated resveratrol analog, prevents platelet aggregation and thrombus formation by targeting the protease-activated receptor 4 pathwayChemico-biological interactionsApril 25, 2022Chiang YC, Wu YS, Kang YF, Wang HC, Tsai MC, Wu CC.

(9) Effect of RFRP-3, the mammalian ortholog of GnIH, on apoptosis and autophagy in porcine ovarian granulosa cells via the p38MAPK pathwayTheriogenologyMarch 1, 2022Zhang X, Li M, Huang M, Peng H, Song X, Chen L, Hu W, Xu W, Luo R, Han D, et al.

(10) Depletion of Fractalkine ameliorates renal injury and Treg cell apoptosis via the p38MAPK pathway in lupus-prone miceExperimental cell researchAugust 15, 2021Ma J, Gong Q, Pan X, Guo P, He L, You Y.

(11) Melatonin impedes prostate cancer metastasis by suppressing MMP-13 expressionJournal of cellular physiologyMay 1, 2021Wang SW, Tai HC, Tang CH, Lin LW, Lin TH, Chang AC, Chen PC, Chen YH, Wang PC, Lai YW, et al.

(12) Juglone prevents human platelet aggregation through inhibiting Akt and protein disulfide isomerasePhytomedicine : international journal of phytotherapy and phytopharmacologyFebruary 1, 2021Kao CC, Kung PH, Tai CJ, Tsai MC, Cheng YB, Wu CC.

(13) Diabetic Endothelial Cells Differentiated From Patient iPSCs Show Dysregulated Glycine Homeostasis and Senescence Associated PhenotypesFrontiers in cell and developmental biologyJanuary 1, 2021Su L, Kong X, Loo SJ, Gao Y, Kovalik JP, Su X, Ma J, Ye L.

(14) Identification and local manipulation of bone marrow vasculature during intravital imagingScientific reportsApril 14, 2020Morikawa T, Tamaki S, Fujita S, Suematsu M, Takubo K.obtained from Sigma. Yohimbine hydrochloride (36805-31) was purchased from NacalaiTesque. U-46619 (sc-201242) was obtained from Santa Cruz Biotechnology. Antibodies The following antibodies were used in this

(15) Qingxin Kaiqiao Fang Inhibits Aβ _25-35-Induced Apoptosis in Primary Cultured Rat Hippocampal Neuronal Cells via the p38 MAPK Pathway: An Experimental Validation and Network Pharmacology StudyEvidence-based complementary and alternative medicine : eCAMJanuary 1, 2020Wang TQ, Lai XX, Xu LT, Shen Y, Lin JW, Gao SY, Hu HY.

(16) Recombinant CC16 inhibits NLRP3/caspase-1-induced pyroptosis through p38 MAPK and ERK signaling pathways in the brain of a neonatal rat model with sepsisJournal of neuroinflammationNovember 27, 2019Zhou R, Yang X, Li X, Qu Y, Huang Q, Sun X, Mu D.

(17) Peimine suppresses interleukin‑1β‑induced inflammation via MAPK downregulation in chondrocytesInternational journal of molecular medicineMay 1, 2019Chen K, Lv ZT, Zhou CH, Liang S, Huang W, Wang ZG, Zhu WT, Wang YT, Jing XZ, Lin H, et al.SMB00446), dissolved in DMSO and stored at ‑20˚C until use. Anisomycin (cat. no. SC‑3524) and U‑46619 (cat. no. SC‑201242) were gained from Santa Cruz Biotechnology, Inc., (Dallas, TX, USA). IL‑1β was obtained from R&D Systems,

(18) A dynamic and screening-compatible nanoluciferase-based complementation assay enables profiling of individual GPCR-G protein interactionsThe Journal of biological chemistryMarch 15, 2019Laschet C, Dupuis N, Hanson J.

(19) Melatonin suppresses lung cancer metastasis by inhibition of epithelial-mesenchymal transition through targeting to TwistClinical science (London, England : 1979)March 15, 2019Chao CC, Chen PC, Chiou PC, Hsu CJ, Liu PI, Yang YC, Reiter RJ, Yang SF, Tang CH.

(20) Loss of ARHGEF1 causes a human primary antibody deficiencyThe Journal of clinical investigationMarch 1, 2019Bouafia A, Lofek S, Bruneau J, Chentout L, Lamrini H, Trinquand A, Deau MC, Heurtier L, Meignin V, Picard C, et al.

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U-46619 Chemicals

U-46619 from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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U-46619 from Santa Cruz Biotechnology, Inc.

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