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Protein Biochemistry
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L-902,688
L-902,688 from Cayman Chemical
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Citations:
(2)
Supplier Page
Supplier Page from
Cayman Chemical for
L-902,688
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Description
A potent and selective agonist of the human PGE2 receptor, EP4 with a Ki value of 0.38 nM and an EC50 value of 0.6 nM; induces thermal hyperalgesia when injected into guinea pig forepaw and increases vasodilation of human pulmonary vein
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
L-902,688
Company
Cayman Chemical
Price
$409.00
Supplier Page
View Company Product Page
Catalog Number
10007712
Quantity
1 mg
Research Area
Cardiovascular System, Cyclooxygenase Pathway, Immunology & Inflammation, Lipid Biochemistry, Neuroscience, Pain Research, Vasculature, Vasodilation
Format
A 5 mg/ml solution in methanol
Molecular Weight
419.5
Purity
≥98%
Storage
-20
Formula
C21H27F2N5O2
Origin
USA
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (2)
(1)
Microglia alter sex-specific cerebellar myelination following placental hormone loss
Nature Communications
November 7, 2025
Jacquelyn Salzbank, Helene Lacaille, Jenah Gaby, Jiaqi J. O’Reilly, Michael Kissner, Claire-Marie Vacher, Anna A. Penn
on plKO sex-specific behavioral phenotype, the PGE2-EP4 agonist,
L-902,688
(
Cayman Chemicals
: Cat #
10007712
), was ordered in a special formulation of neat solid. It was then reconstituted in 0.9% Sodium Chloride.
(2)
Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling
Nat Commun
February 7, 2025
Jeonghyeon Kwon, Haruya Kawase, Kenny Mattonet, Stefan Guenther, Lisa Hahnefeld, Jamal Shamsara, Jan Heering, Michael Kurz, Sina Kirchhofer, Cornelius Krasel,
et al.
purchased from
PerkinElmer
.
Coelenterazine h
(
S2001
) was from
Promega
GmbH.
Butaprost
(
13741
), L-902668 (
10007712
), 17-phenly trinor PGE2 (17-pt-PGE2,
14810
),
leukotriene B4
(LTB4,
20110
), PGE2 for
FRET
experiments
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L-902,688 from Cayman Chemical
Supplier Page
View Company Product Page
$409.00
Product Specs
Company Info
Citations
Reviews
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