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Protein Biochemistry
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CAY10598
CAY10598 from Cayman Chemical
Be the first to write a review!
Citations:
(8)
Supplier Page
Supplier Page from
Cayman Chemical for
CAY10598
Request Info
Description
A very potent agonist of EP4, binding with a Ki value of 1.2 nM; does not bind EP1, EP2, EP3, DP, FP, IP, or TP receptors
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
CAY10598
Company
Cayman Chemical
Price
$579.00
Supplier Page
View Company Product Page
Catalog Number
13281
Quantity
5 mg
Format
A 5 mg/ml solution in ethanol
Purity
≥98%
Molecular Weight
383.5
Research Area
Bone Growth & Remodeling, Cardiovascular System, Cyclooxygenase Pathway, Endocrinology & Metabolism, Immunology & Inflammation, Kidney & Renal Disease, Lipid Biochemistry, Neuroprotection, Neuroscience
Storage
-20
Formula
C21H29N5O2
Origin
USA
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Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (8)
(1)
Rab23 GTPase and IFT43 regulate the trafficking of prostaglandin E receptor 4 to primary cilia
Communications Biology
December 10, 2025
Yewei Chen, Yating Zhou, Yao Qi, Tingting Miao, Jianan Shi, Daqing Jin, Tao P. Zhong
For ciliary cAMP imaging, HEK293T cells expressing NPHP3-G-Flamp1 were treated with DMSO,
CAY10598
(
13281
,
Cayman
), or Forskolin (T2939, Topscience) to modulate cAMP levels. Live-cell
fluorescence imaging
for
(2)
m(6)A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1
Cell metabolism
October 1, 2024
Xiao L, De Jesus DF, Ju CW, Wei JB, Hu J, DiStefano-Forti A, Tsuji T, Cero C, Männistö V, Manninen SM,
et al
.
Lipofectamine 3000 Transfection Reagent
,
Thermo Fisher Scientific
,
L3000008
CAY10598
(1mg) (potent
EP4
agonist),
Cayman Chemical
,
13281
"
CP 544,326
(1mg) (potent EP2 agonist)",
Cayman Chemical
,
22945
17-phenyl trinor Prostaglandin E2
(1mg)
(3)
Prostaglandin E2 affects mitochondrial function in adult mouse cardiomyocytes and hearts
Prostaglandins, Leukotrienes and Essential Fatty Acids
March 6, 2024
Timothy D. Bryson, Matthew Zurek, Carlin Moore, David Taube, Indrani Datta, Albert Levin, Pamela Harding
used. 2.11. Chemicals PGE2 (catalog #
14010
), sulprostone (catalog #
14765
), and
CAY10598
(catalog #
13281
),
Rotenone
(catalog #
13995
), and Antimycin (catalog #
19433
) were all purchased from
Cayman Chemical
(4)
Targeting EP2 receptor with multifaceted mechanisms for high-risk neuroblastoma
Cell reports
June 21, 2022
Hou R, Yu Y, Sluter MN, Li L, Hao J, Fang J, Yang J, Jiang J.
CAS# 363-24-6
Butaprost
,
Cayman Chemical
,Cat#
13740
; CAS# 69685-22-9
CAY10598
,
Cayman Chemical
,Cat#
13281
; CAS# 346673-06-1
PF-04418948
,
Cayman Chemical
,Cat#
15016
; CAS# 1078166-57-0 GW627368X,
Cayman Chemical
,Cat#
(5)
Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E2 Signaling
Frontiers in Bioengineering and Biotechnology
July 21, 2021
Kristy E. Gilman, Jean M. Camden, Lucas T. Woods, Gary A. Weisman, Kirsten H. Limesand
sulprostone (EP3R agonist;
Cayman Chemical
, no.
14765
) and
CAY10598
(
EP4R
agonist;
Cayman Chemical
, no.
13281
). Cells were serum-starved for 2 h prior to treatment. All compounds were solubilized in DMSO, mixed
(6)
Targeted inhibition of GRK2 kinase domain by CP-25 to reverse fibroblast-like synoviocytes dysfunction and improve collagen-induced arthritis in rats
Acta pharmaceutica Sinica. B
July 1, 2021
Han C, Li Y, Zhang Y, Wang Y, Cui D, Luo T, Zhang Y, Liu Q, Li H, Wang C,
et al
.
GSK180736A
(Cat.
HY-18990
) was obtained from
MedChemExpress
(USA). PGE2 (Cat.
14010
) and
CAY10598
(Cat.
13281
) were purchased from
Cayman Chemical
(USA). Paroxetine was purchased from Zhejiang Huahai Pharmaceutical
(7)
Endothelial cell prostaglandin E2 receptor EP4 is essential for blood pressure homeostasis
JCI insight
July 9, 2020
Xu H, Fang B, Du S, Wang S, Li Q, Jia X, Bao C, Ye L, Sui X, Qian L,
et al
.
Cell Signaling Technology
. PGE2 (catalog
14010
), PGE1-OH (catalog
13020
),
CAY10580
(catalog
16835
),
CAY10598
(catalog
13281
), sulprostone (catalog
14765
), and butaprost (catalog
13740
) were purchased from
Cayman Chemical
. l-NAME
(8)
Altered expression and signalling of EP2 receptor in nasal polyps of AERD patients: role in inflammation and remodelling
Rhinology journal
January 12, 2017
L. Machado-Carvalho, R. Torres, M. Perez-Gonzalez, I. Alobid, J. Mullol, L. Pujols, J. Roca-Ferrer, C. Picado
specific
EP2
receptor agonist butaprost free-acid (
13741
,
Cayman
) and EP4 receptor agonist
CAY10598
(
13281
,
Cayman
) or forskolin (
F3917
,
Sigma
), an AC activator, for 15min at 37ºC. The concentration of intracellular
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CAY10598 from Cayman Chemical
Supplier Page
View Company Product Page
$579.00
Product Specs
Company Info
Citations
Reviews
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