Wortmannin from Cayman Chemical

An irreversible PI3K inhibitor (IC50 = 1-10 nM); inhibits Drosophila, murine, and human class II PI3Ks (IC50s = 5, 50, 450 nM, respectively); ~50-100-fold selective for PI3Ks over mTOR, DNA-PK, PI4K, MLCK, and p38 MAPK; inhibits polo-like kinase 1 (IC50 = 24 nM) and polo-like kinase 3 (IC50 = 49 nM)