(±)-Rolipram from Cayman Chemical

Product Specs
Item(±)-Rolipram
CompanyCayman Chemical
Price $32.00Supplier Page View Company Product Page
Catalog Number10011132
Research AreaBehavioral Neuroscience, cAMP Signaling, Cell Biology, Cell Signaling, Immunology & Inflammation, Inflammatory Lipid Mediators, Innate Immunity, Leukotrienes, Neuroscience, Schizophrenia & Psychosis
FormatA crystalline solid
Molecular Weight275.3
Purity≥98%
Storage-20
FormulaC16H21NO3
OriginUSA
TypeInhibitors
Quantity5 mg

Specifications/Features

Ki, IC, EC, or working concentration: IC50: 200 nM for C5a-stimulated LTC4 synthesis in eosinophils
IC50: 360 nM for lipopolysaccharide-induced TNF synthesis in monocytes

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Dissection of Gαs and Hedgehog Signaling Cross-talk Reveals Therapeutic Opportunities to Target Hedgehog-Dependent TumorsCancer ResearchFebruary 16, 2026Sarah Krantz, Braden A. Bell, Katherine Lund, Natalia Salinas Parra, Yeap Ng, Natalia De Oliveira Rosa, Saikat Mukhopadhyay, Brad St. Croix, Kavita Y. Sarin, Roberto Weigert, et al.tamoxifen. Mice were randomized to receive drug treatments after tumor induction. Rolipram (Cayman Chemical, 10011132) and BRL50481 (Cayman Chemical, 16899) were injected intraperitoneally at 10 mg/kg/day, individually

(2) Dissection of Gαs and Hedgehog signaling crosstalk reveals therapeutic opportunities to target adenosine receptor 2b in Hedgehog-dependent tumorsbioRxivFebruary 28, 2025Sarah Krantz, Braden Bell, Katherine Lund, Natalia Salinas Salinas Parra, Yeap Ng, Natalia De Oliveira Rosa, Saikat Mukhopadhyay, Brad St St Croix, Kavita Y Sarin, Roberto Weigert, et al.utilizing a random number generator. For individual PDE inhibitor treatment, rolipram (Cayman Chemicals 10011132) and BRL50481 (Cayman Chemicals 16899) were injected intraperitoneally at 10mg/kg/day for 29 days, 8

(3) Validation of a functional human AD model with four AD therapeutics utilizing patterned ipsc-derived cortical neurons integrated with microelectrode arraysScientific reportsOctober 22, 2024Caneus J, Autar K, Akanda N, Grillo M, Long CJ, Jackson M, Lindquist S, Guo X, Morgan D, Hickman JJ.drugs used in the treatment of AD were used in this study, including Rolipram (Cayman Chemicals, Cat. # 10011132), Saracatinib (Cayman Chemicals, Cat. # 379231-04-6), Memantine (Cayman Chemicals, Cat # 14184) and

(4) Clampdown of inflammation in aging and anticancer therapies by limiting upregulation and activation of GPCR, CXCR4NPJ aging and mechanisms of diseaseJanuary 1, 2018Nair RR, Madiwale SV, Saini DK.USA; 1 mg/ml in water) at 1 µg/ml; PTx (Merck Inc., USA), Rolipram (Cayman Chemical Co., USA; Cat No. 10011132), Plerixafor (Cayman Chemical Co., USA; Cat No. 1001132) and 8-Bromo-Cyclic AMP (sodium salt) (Sigma Aldrich

(5) Rosmarinic acid suppresses adipogenesis, lipolysis in 3T3-L1 adipocytes, lipopolysaccharide-stimulated tumor necrosis factor-α secretion in macrophages, and inflammatory mediators in 3T3-L1 adipocytesFood & nutrition researchJanuary 1, 2017Rui Y, Tong L, Cheng J, Wang G, Qin L, Wan Z.(cat. no. 10006726), forskolin (cat. no. 11018), wortmannin (cat. no. 10010591), rolipram (cat. no. 10011132), cilostamide (cat. no. 14455), and SB431542 (cat. no. 13031) were obtained from Cayman Chemicals (Ann

(6) Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancerCell death & diseaseMay 5, 2016Taniguchi T, Iizumi Y, Watanabe M, Masuda M, Morita M, Aono Y, Toriyama S, Oishi M, Goi W, Sakai T.targeting DDX5. Materials and Methods Reagents. trans-Resveratrol (Cat. No. 70675) and rolipram (Cat. No. 10011132) were purchased from Cayman Chemical (Ann Arbor, MI, USA). Purified recombinant proteins of Homo sapiens

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(±)-Rolipram

(±)-Rolipram

(±)-Rolipram from Cayman Chemical

Description

Specifications/Features

Cayman Chemical

Citations (6)

Reviews

(±)-Rolipram from Cayman Chemical

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