SC79, Akt activator from Abcam

Product Specs
ItemSC79, Akt activator
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab146428
Quantity5 mg, 25 mg
TypeActivator/Agonist
Molecule NameSC79, Akt activator

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) PLAUR facilitates the progression of clear cell renal cell carcinoma by activating the PI3K/AKT/mTOR signaling pathwayPeerJJune 27, 2024Tianzi Qin, Minyu Huang, Wenjuan Wei, Wei Zhou, Qianli Tang, Qun Huang, Ning Tang, Shasha GaiHIF-α and MMP9 was decreased by this pathway, which could be reversed by the AKT activator (SC-79; ab146428, Abcam, Cambridge, UK) (P < 0.05, Fig. 8A). Additionally, The proliferation, migration, and invasion

(2) Methyl vinyl ketone and its analogs covalently modify PI3K and alter physiological functions by inhibiting PI3K signalingThe Journal of biological chemistryMarch 1, 2024Morimoto A, Takasugi N, Pan Y, Kubota S, Dohmae N, Abiko Y, Uchida K, Kumagai Y, Uehara T.from BD Transduction Laboratories. Antibodies against phospho-PI3K p85a (Tyr607) (ab182651) and SC-79 (ab146428) were purchased from Abcam. Antibodies against FLAG (DYKDDDDK) (A8592) were purchased from Sigma–Aldrich.

(3) Silencing of NACC1 inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma cells via regulating the AKT/mTOR signaling pathwayOncology LettersOctober 12, 2021Zhengyong Cao, Hong Chen, Xiaoli Mei, Xiaobo Liof Biotechnology) in a 37°C, 5% CO2 incubator. For treatment with the AKT activator SC79 (cat. no. ab146428, Abcam), cells were exposed to 5 µg/ml SC79 for 48 h at 37°C (14). Cell transfection For NACC1-knockdown,

(4) Germacrone induces lung cancer cell apoptosis and cell cycle arrest via the Akt/MDM2/p53 signaling pathwayMolecular Medicine ReportsApril 15, 2021Yang Zhao, Jie Cai, Kaihu Shi, Hang Li, Jin Du, Dinghui Hu, Zuntao Liu, Wei Wangsynchronized in serum-free medium for 24 h. Subsequently, cells were treated with 8 µg/ml SC79 (cat. no. ab146428; Abcam) or GM (50, 100 or 200 µM) at 37°C for 24 h. Cells in the control group were treated with equal

(5) lncRNA CADM1-AS1 inhibits cell-cycle progression and invasion via PTEN/AKT/GSK-3β axis in hepatocellular carcinomaCancer management and researchJanuary 1, 2019Wang F, Qi X, Li Z, Jin S, Xie Y, Zhong H.purchased from Cell Signaling Technology (Danvers, MA, USA). The speciﬁc AKT inhibitor SC79 (Abcam, #ab146428). GAPDH (1:5000, #10494-1-AP, proteintech) antibody was used as the reference control. In vivo tumorigenicity All

(6) Pectolinarigenin inhibits non‑small cell lung cancer progression by regulating the PTEN/PI3K/AKT signaling pathwayOncology ReportsOctober 2, 2018Fei Xu, Xuan Gao, Huiyun PanInc. (Lincoln, NE, USA). PTEN inhibitor SF1670 (cat. no. ab141303) and AKT activator SC79 (cat. no. ab146428) were purchased from Abcam (Cambridge, UK). SF1670 and/or SC79 (10 µM) were applied to the culture medium

(7) Beta-Arrestin 1 Mediates Liver Thyrotropin Regulation of Cholesterol Conversion Metabolism via the Akt-Dependent PathwayInternational Journal of EndocrinologyMay 2, 2018Shaona Niu, Hui Li, Wenbin Chen, Jiajun Zhao, Ling Gao, Tao Bohours in serum-free DMEM. Total protein was extracted according to standard protocols. SC79 (Abcam, ab146428) was used as an AKT activator. 2.3. Genetic Manipulation of ARRBs The CRISPR/Cas9 system was used

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SC79, Akt activator from Abcam

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SC79, Akt activator from Abcam

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