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Protein Biochemistry
Chemicals and Reagents
SC79, Akt activator
SC79, Akt activator from Abcam
Be the first to write a review!
Citations:
(7)
Supplier Page
Supplier Page from
Abcam for
SC79, Akt activator
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
SC79, Akt activator
Company
Abcam
Price
Supplier Page
View Company Product Page
Catalog Number
ab146428
Quantity
5 mg, 25 mg
Type
Activator/Agonist
Molecule Name
SC79, Akt activator
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Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (7)
(1)
PLAUR facilitates the progression of clear cell renal cell carcinoma by activating the PI3K/AKT/mTOR signaling pathway
PeerJ
June 27, 2024
Tianzi Qin, Minyu Huang, Wenjuan Wei, Wei Zhou, Qianli Tang, Qun Huang, Ning Tang, Shasha Gai
HIF-α and MMP9 was decreased by this pathway, which could be reversed by the AKT activator (SC-79;
ab146428
,
Abcam
, Cambridge, UK) (P < 0.05, Fig. 8A). Additionally, The proliferation, migration, and invasion
(2)
Methyl vinyl ketone and its analogs covalently modify PI3K and alter physiological functions by inhibiting PI3K signaling
The Journal of biological chemistry
March 1, 2024
Morimoto A, Takasugi N, Pan Y, Kubota S, Dohmae N, Abiko Y, Uchida K, Kumagai Y, Uehara T.
from BD Transduction Laboratories. Antibodies against phospho-PI3K p85a (Tyr607) (
ab182651
) and SC-79 (
ab146428
) were purchased from
Abcam
. Antibodies against FLAG (DYKDDDDK) (
A8592
) were purchased from
Sigma–Aldrich
.
(3)
Silencing of NACC1 inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma cells via regulating the AKT/mTOR signaling pathway
Oncology Letters
October 12, 2021
Zhengyong Cao, Hong Chen, Xiaoli Mei, Xiaobo Li
of Biotechnology) in a 37°C, 5% CO2 incubator. For treatment with the
AKT
activator
SC79
(cat. no.
ab146428
,
Abcam
), cells were exposed to 5 µg/ml
SC79
for 48 h at 37°C (14).
Cell transfection
For NACC1-
knockdown
,
(4)
Germacrone induces lung cancer cell apoptosis and cell cycle arrest via the Akt/MDM2/p53 signaling pathway
Molecular Medicine Reports
April 15, 2021
Yang Zhao, Jie Cai, Kaihu Shi, Hang Li, Jin Du, Dinghui Hu, Zuntao Liu, Wei Wang
synchronized in serum-free medium for 24 h. Subsequently, cells were treated with 8 µg/ml
SC79
(cat. no.
ab146428
;
Abcam
) or GM (50, 100 or 200 µM) at 37°C for 24 h. Cells in the
control group
were treated with equal
(5)
lncRNA CADM1-AS1 inhibits cell-cycle progression and invasion via PTEN/AKT/GSK-3β axis in hepatocellular carcinoma
Cancer management and research
January 1, 2019
Wang F, Qi X, Li Z, Jin S, Xie Y, Zhong H.
purchased from
Cell Signaling Technology
(Danvers, MA, USA). The specific AKT inhibitor
SC79
(
Abcam
, #
ab146428
). GAPDH (
1:5000
, #10494-1-AP, proteintech) antibody was used as the reference control. In vivo tumorigenicity All
(6)
Pectolinarigenin inhibits non‑small cell lung cancer progression by regulating the PTEN/PI3K/AKT signaling pathway
Oncology Reports
October 2, 2018
Fei Xu, Xuan Gao, Huiyun Pan
Inc. (Lincoln, NE, USA). PTEN
inhibitor
SF1670 (cat. no.
ab141303
) and
AKT
activator
SC79
(cat. no.
ab146428
) were purchased from
Abcam
(Cambridge, UK). SF1670 and/or SC79 (10 µM) were applied to the culture medium
(7)
Beta-Arrestin 1 Mediates Liver Thyrotropin Regulation of Cholesterol Conversion Metabolism via the Akt-Dependent Pathway
International Journal of Endocrinology
May 2, 2018
Shaona Niu, Hui Li, Wenbin Chen, Jiajun Zhao, Ling Gao, Tao Bo
hours in serum-free DMEM. Total protein was extracted according to standard protocols.
SC79
(
Abcam
,
ab146428
) was used as an
AKT
activator. 2.3. Genetic Manipulation of ARRBs The
CRISPR/Cas9
system was used
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SC79, Akt activator from Abcam
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