Rotenone, mitochondrial electron transport chain inhibitor from Abcam

Product Specs
ItemRotenone, mitochondrial electron transport chain inhibitor
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab143145
Quantity1 g, 5 g
Purity0.97
TypeInhibitor, inhibitor
Molecule NameRotenone

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) EZH2 loss during metabolic stress drives restoration of MHC Class I machinery in melanomaiScienceJune 20, 2025Jacob L. Edmondson, Megan R. Reed, Daniel Fil, Billie Heflin, Alyson McKinnon, Michael A. Bauer, Lauren C. Morehead, Nathan L. Avaritt, Mary Phillips, Sean D. Taverna, et al.S1378 Tazemetostat,SelleckChem,Cat# S7128 Oligomycin,APExBio,Cat# A5588 FCCP,Cayman Chemical,Cat# 15218 Rotenone,Abcam,Cat# ab143145 Antimycin A,Thermo Fisher,Cat# J63522-MA 2-Deoxyglucose,Millipore,Cat# 154-17-6 Metformin,Millipore,Cat#

(2) Neuroprotective efficacy of berberine and caffeine against rotenone-induced neuroinflammatory and oxidative disturbances associated with Parkinson's disease via inhibiting α-synuclein aggregation and boosting dopamine releaseInflammopharmacologyApril 1, 2025Waheeb TS, Abdulkader MA, Ghareeb DA, Moustafa ME.NIH guidelines on the management and utilization of laboratory animals. Drug preparation Rotenone (ab143145) was purchased from Abcam (Cambridge, UK). It was suspended in sunflower oil at a concentration of 1.5

(3) Lysosomes drive the piecemeal removal of mitochondrial inner membraneNatureAugust 29, 2024Akriti Prashar, Claudio Bussi, Antony Fearns, Mariana I. Capurro, Xiaodong Gao, Hiromi Sesaki, Maximiliano G. Gutierrez, Nicola L. Jonesused at 50 μM for 24h. Oligomycin (Santa Cruz, #sc201551) was used at 10μM for 24h. Rotenone (Abcam, #ab143145) was used at 10 μM for 24h. VBIT-12 (Cayman Chemicals, #31445) was used at 10μM for 24h. ML-SA1 (Sigma,

(4) Thioredoxin is a metabolic rheostat controlling regulatory B cellsNature immunologyMay 1, 2024Bradford HF, McDonnell TCR, Stewart A, Skelton A, Ng J, Baig Z, Fraternali F, Dunn-Walters D, Isenberg DA, Khan AR, et al.incubated with 1 mM 2-DG, 10 μM etomoxir, 1 μM rotenone, 10 nM antimycin A (Abcam; ab254445, ab142242, ab143145, ab141904), 500 nM BPTES (Tocris, 5301) or 100 μM Malonyl coenzyme A (Sigma-Aldrich, M4263). B cells

(5) LC3 subfamily in cardiolipin-mediated mitophagy: a comparison of the LC3A, LC3B and LC3C homologsAutophagyDecember 1, 2022Iriondo MN, Etxaniz A, Varela YR, Ballesteros U, Hervás JH, Montes LR, Goñi FM, Alonso A.(ab26628), anti-LC3B (ab51520) anti-LC3C (ab150367) anti-COX4I/COX-IV (ab14744) antibodies and rotenone (ab143145) were purchased from Abcam. Anti-ACTB/actin (sc-8432), HRP-conjugated anti-mouse (sc-516,102), HRP-conjugated

(6) Continuous Inflammatory Stimulation Leads via Metabolic Plasticity to a Prometastatic Phenotype in Triple-Negative Breast Cancer CellsCellsMay 31, 2021Morein D, Rubinstein-Achiasaf L, Brayer H, Dorot O, Pichinuk E, Ben-Yaakov H, Meshel T, Pasmanik-Chor M, Ben-Baruch A.rate (ECAR) measurements were taken at basal rate followed by injections of mixture of Rot (0.5 μM; #ab143145, Abcam, Cambridge, MA, USA) +AA (as above), and then 2-Deoxy-D-Glucose (2-DG; 50 mM; #ab142242, Abcam). Following

(7) Bmal1 integrates mitochondrial metabolism and macrophage activationeLifeMay 12, 2020Alexander RK, Liou YH, Knudsen NH, Starost KA, Xu C, Hyde AL, Liu S, Jacobi D, Liao NS, Lee CH.ab141829; CAS: 1404-19-9,Used 2 μM final concentration "Chemical compound, drug",Rotenone,Abcam,Cat# ab143145 CAS: 83-79-4,Used 1 μM final concentration "Chemical compound, drug",Antimycin A,Sigma-Aldrich,Cat#

(8) Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum PlatformDevelopmental cellSeptember 9, 2019Zachari M, Gudmundsson SR, Li Z, Manifava M, Shah R, Smith M, Stronge J, Karanasios E, Piunti C, Kishi-Itakura C, et al.702675-74-9 Oligomycin,Tocris,4110; CAS: 579-13-5 CCCP,Tocris,0452; CAS: 555-60-2 Rotenone,Abcam,ab143145 Mdivi-1,Enzo,BML-CM127 VPS34-IN1,Kind gift from Ian Ganley,N/A Mitot Tracker Deep Red FM,Thermo Fisher

(9) Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and CancersCell reportsAugust 27, 2019Chatterjee N, Pazarentzos E, Mayekar MK, Gui P, Allegakoen DV, Hrustanovic G, Olivas V, Lin L, Verschueren E, Johnson JR, et al.S1148 NAC,Sigma-Aldrich,Cat# A7250 H2DCFDA,Thermo Fisher Scientific,Cat# D399 Rotenone (ETC complex I inhibitor),Abcam,Cat# ab143145 Oligomycin (ATP synthase inhibitor),Abcam,Cat# ab141829 2-DG,Sigma-Aldrich,Cat# D8375 Human TNF-α,Peprotech,Cat#

(10) VDAC2 interacts with PFKP to regulate glucose metabolism and phenotypic reprogramming of glioma stem cellsCell death & diseaseSeptember 24, 2018Zhou K, Yao YL, He ZC, Chen C, Zhang XN, Yang KD, Liu YQ, Liu Q, Fu WJ, Chen YP, et al.manufacturer’s protocol. Briefly, cells were treated with 2-DG (25 mM, D0051, TCI) or rotenone (50 μM, ab143145, Abcam, Cambridge, UK) for 1 h. The indicated cells were lysed and centrifuged at 12 000 × g for 5 min

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Rotenone, mitochondrial electron transport chain inhibitor from Abcam

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Rotenone, mitochondrial electron transport chain inhibitor from Abcam

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