Ruxolitinib from Santa Cruz Biotechnology, Inc.

Product Specs
ItemRuxolitinib
CompanySanta Cruz Biotechnology, Inc.
Price $246.00Supplier Page View Company Product Page
Catalog Numbersc-364729
Quantity5 mg
TypeBiochemical Reagents
Molecular Weight306.37

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Targeting PAR1 activation in JAK2V617F-driven philadelphia-negative myeloproliferative neoplasms: Unraveling its role in thrombosis and disease progressionNeoplasiaMarch 14, 2025İldeniz Uslu-Biçak, Meliha Nalçaci, Selçuk SözerVorapaxar (SCH530348, MedChemExpress, Monmouth Junction, NJ, USA) and JAK2 inhibitor, Ruxolitinib (sc-364729, Santa Cruz Biotechnology, Dallas, Texas, USA) for the analysis. For all MNC samples, thrombin (1-10

(2) Antigen-specific downregulation of miR-150 in CD4 T cells promotes cell survivalFrontiers in immunologyJanuary 1, 2023Ménoret A, Agliano F, Karginov TA, Karlinsey KS, Zhou B, Vella AT.from EMD Millipore Corporation (Billerica, MA). Human rIL-2 was obtained from the NIH. Ruxolitinib (sc-364729) was purchased from Santa Cruz Biotechnology (Santa Cruz, CA). Lipopolysaccharide (LPS) (from salmonella enterica

(3) Synthetic lethal combination targeting BET uncovered intrinsic susceptibility of TNBC to ferroptosisScience advancesAugust 1, 2020Verma N, Vinik Y, Saroha A, Nair NU, Ruppin E, Mills G, Karn T, Dubey V, Khera L, Raj H, et al.

(4) Signal transducer and activator of transcription (STAT) 1 and STAT3 are expressed in the human ovary and have Janus kinase 1-independent functions in the COV434 human granulosa cell lineReproduction, fertility, and developmentAugust 1, 2020Frost ER, Ford EA, Peters AE, Reed NL, McLaughlin EA, Baker MA, Lovell-Badge R, Sutherland JM.

(5) The Dose Dependent Effects of Ruxolitinib on the Invasion and Tumorigenesis in Gliomas Cells via Inhibition of Interferon Gamma-Depended JAK/STAT Signaling PathwayJournal of Korean Neurosurgical SocietyJuly 1, 2020Delen E, Doğanlar O.

(6) Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral LeishmaniasisCell reportsFebruary 25, 2020Kumar R, Bunn PT, Singh SS, Ng SS, Montes de Oca M, De Labastida Rivera F, Chauhan SB, Singh N, Faleiro RJ, Edwards CL, et al.Red blood cell lysing buffer Hybri-Max,Sigma-Aldrich,Cat#R7757 RNAlater,Invitrogen,Cat#AM7021 Ruxolitinib,ChemieTek,Cat#CT-INCB "Ruxolitinib, 5 mg",Santa Cruz Biotechnology,Cat#sc-364729 Tissue-Tek® O.C.T. Compound,Sakura,Cat#4583 Trizma® hydrochloride solution (TRIS-HCl),Sigma-Aldrich,Cat#T2444 Trypan

(7) The mechanism of how CD95/Fas activates the Type I IFN/STAT1 axis, driving cancer stemness in breast cancerScientific reportsJanuary 28, 2020Qadir AS, Stults AM, Murmann AE, Peter ME.

(8) Inhibition of the Invasion of Human Glioblastoma U87 Cell Line by Ruxolitinib: A Molecular Player of miR-17 and miR-20a Regulating JAK/STAT PathwayTurkish neurosurgeryJanuary 1, 2020Delen E, Doganlar O, Doganlar ZB, Delen O.

(9) Increased SLAMF7(high) monocytes in myelofibrosis patients harboring JAK2V617F provide a therapeutic target of elotuzumabBloodSeptember 5, 2019Maekawa T, Kato S, Kawamura T, Takada K, Sone T, Ogata H, Saito K, Izumi T, Nagao S, Takano K, et al.with DMEM with or without Elo and with other agents, such as Rom (TPO-R agonist), Rux (JAK inhibitor) (SC-364729; Santa Cruz Biotechnology, Dallas, TX), and interferon-a2 (IFN-a2) (130-093-873; Miltenyi Biotec, Bergish

(10) An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunityProceedings of the National Academy of Sciences of the United States of AmericaAugust 27, 2019Schmidt N, Domingues P, Golebiowski F, Patzina C, Tatham MH, Hay RT, Hale BG.(Sigma-Aldrich; M7449), lactacystin (Enzo Life Sciences; BML-PI104-0200), ruxolitinib (Santa Cruz; sc-364729), or BX-795 (Sigma-Aldrich; SML0694) was added to the medium at the indicated concentration. Virus titers

(11) CITED2 mediates the cross-talk between mechanical loading and IL-4 to promote chondroprotectionAnnals of the New York Academy of SciencesApril 1, 2019He Z, Leong DJ, Xu L, Hardin JA, Majeska RJ, Schaffler MB, Thi MM, Yang L, Goldring MB, Cobelli NJ, et al.

(12) Paracrine costimulation of IFN-γ signaling by integrins modulates CD8 T cell differentiationProceedings of the National Academy of Sciences of the United States of AmericaNovember 6, 2018Krummel MF, Mahale JN, Uhl LFK, Hardison EA, Mujal AM, Mazet JM, Weber RJ, Gartner ZJ, Gérard A.

(13) Janus kinase JAK1 maintains the ovarian reserve of primordial follicles in the mouse ovaryMolecular human reproductionNovember 1, 2018Sutherland JM, Frost ER, Ford EA, Peters AE, Reed NL, Seldon AN, Mihalas BP, Russel DL, Dunning KR, McLaughlin EA.

(14) Blockade of JAK2/STAT3 intensifies the anti-tumor activity of arsenic trioxide in acute myeloid leukemia cells: Novel synergistic mechanism via the mediation of reactive oxygen speciesEuropean journal of pharmacologySeptember 5, 2018Mesbahi Y, Zekri A, Ghaffari SH, Tabatabaie PS, Ahmadian S, Ghavamzadeh A.

(15) T cell-directed IL-17 production by lung granular γδ T cells is coordinated by a novel IL-2 and IL-1β circuitMucosal immunologySeptember 1, 2018Ménoret A, Buturla JA, Xu MM, Svedova J, Kumar S, Rathinam VAK, Vella AT.(PMA) and Brefeldin A (BFA) were purchased from EMD Millipore Corporation (Billerica, MA). Ruxolitinib (sc-364729) was purchased from Santa Cruz Biotechnology (Santa Cruz, CA). Heparin was purchased from Thermo Fisher

(16) Measles Virus Genotype D Wild Strains Suppress Interferon-Stimulated Gene Expression More Potently than Laboratory Strains in SiHa CellsViral immunologyJune 1, 2016Jinushi M, Yamamoto S, Ogasawara N, Nagano H, Hashimoto S, Tsutsumi H, Himi T, Yokota S.

(17) Costimulation Endows Immunotherapeutic CD8 T Cells with IL-36 Responsiveness during Aerobic GlycolysisJournal of immunology (Baltimore, Md. : 1950)January 1, 2016Tsurutani N, Mittal P, St Rose MC, Ngoi SM, Svedova J, Menoret A, Treadway FB, Laubenbacher R, Suárez-Ramírez JE, Cauley LS, et al.

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Ruxolitinib Chemicals

Ruxolitinib from Santa Cruz Biotechnology, Inc.

Santa Cruz Biotechnology, Inc.

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Ruxolitinib from Santa Cruz Biotechnology, Inc.

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