Fatostatin (hydrobromide) from Cayman Chemical

Product Specs
ItemFatostatin (hydrobromide)
CompanyCayman Chemical
Price $105.00Supplier Page View Company Product Page
Catalog Number13562
Quantity10 mg
Research AreaCancer, Cell Biology, Cell Signaling, Diabetes, Dyslipidemias, Endocrinology & Metabolism, Growth Factor Receptors, Metabolic Diseases, Nutrient Sensing, Obesity, Transcription Factors
FormatA crystalline solid
Molecular Weight375.3
Purity≥95%
TypeInhibitors
OriginCHN
FormulaC18H18N2S • HBr
Storage-20

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Programmed cell revival from imminent cell death enhances tissue repair and regenerationThe EMBO JournalAugust 21, 2025Kollori Dhar, Kautilya Kumar Jena, Subhash Mehto, Rinku Sahu, Krushna C Murmu, Atharva Anand Mahajan, Sibaram Behera, Ravi Kiran Putchala, Reuben Jacob Mathew, Ramyasingh Bal, et al.Cytochalasin D,Millipore-Sigma,Cat#250255 Nocodazole,Millipore-Sigma,Cat#M1404 pp242,InvivoGen,Cat#inh-pp242 AY 9944,Cayman Chemical,Cat#14611 Fatostatin (hydrobromide),Cayman Chemical,Cat#13562 IWP-4,Cayman Chemical,Cat#13954 ML385,Millipore-Sigma,Cat#SML1833 Epigallocatechin gallate (EGCG),Millipore-Sigma,Cat#E4143 KU-55933,Millipore-Sigma,Cat#SML1109 GSK690693,Cayman Chemical

(2) A lactate-SREBP2 signaling axis drives tolerogenic dendritic cell maturation and promotes cancer progressionScience ImmunologyMay 10, 2024Michael P. Plebanek, Yue Xue, Y-Van Nguyen, Nicholas C. DeVito, Xueying Wang, Alisha Holtzhausen, Georgia M. Beasley, Balamayooran Theivanthiran, Brent A. Hanksassigned to a group. For fatostatin treatments, mice were treated with fatostatin [Cayman Chemicals, 13562; 30 mg/kg, 150 μl, 5% dimethyl sulfoxide (DMSO)] via intraperitoneal injection every 2 days. For syngeneic

(3) Targeting ABCG1 and SREBP-2 mediated cholesterol homeostasis ameliorates Zika virus-induced ocular pathologyiScienceMarch 15, 2024Singh S, Wright RE 3rd, Giri S, Arumugaswami V, Kumar A.,Life Technologies,Cat#15596018 FBS (Fetal Bovine Serum),CPS Serum,Cat#FBS-500-HI Fatostatin,Cayman chemical,Cat#13562 LXR-623,Cayman chemical,Cat#21117 SR-9238,Cayman chemical,Cat#18771 ,, Critical commercial assays,Critical

(4) Inhibition of the SREBP pathway prevents SARS-CoV-2 replication and inflammasome activationLife Science AllianceNovember 1, 2023Vinicius Cardoso Soares, Suelen Silva Gomes Dias, Julia Cunha Santos, Isaclaudia G Azevedo-Quintanilha, Isabela Batista Gonçalves Moreira, Carolina Q Sacramento, Natalia Fintelman-Rodrigues, Jairo R Temerozo, Marcos Alexandre Nunes da Silva, Debora Ferreira Barreto-Vieira, et al.without pretreatment for 2 h with pharmacological inhibitors of SREBP activation, such as fatostatin (13562; Cayman), AM580 (A8843; Sigma-Aldrich) and betulin (11041; Cayman), and the pharmacological inhibitor

(5) Systematic elucidation of genetic mechanisms underlying cholesterol uptakeCell GenomMay 10, 2023Hamilton MC, Fife JD, Akinci E, Yu T, Khowpinitchai B, Cha M, Barkal S, Thi TT, Yeo GHT, Ramos Barroso JP, et al.,Thermo Fisher Scientific,Cat#L3483 NGI-1,Cayman,Cat#31519 ATN-224,Cayman,Cat#23553 Pyripyropene A,Cayman,Cat#11896 Fatostatin,Cayman,Cat#13562 KX2-391,Cayman,Cat#21429 MHY1485,Cayman,Cat#18008 GW3965,Cayman,Cat#10054 Rocaglamide A,MedChemExpress,Cat#HY-19356 Rho Activator II

(6) Inflammatory stress signaling via NF-kB alters accessible cholesterol to upregulate SREBP2 transcriptional activity in endothelial cellseLifeAugust 12, 2022Fowler JWM, Zhang R, Tao B, Boutagy NE, Sessa WC.Biomedical,770230, "chemical compound, drug",EGM2,Lonza,CC-3162, "chemical compound, drug",Fatostatin,Cayman,13562, "chemical compound, drug",Filipin,Cayman,70440, "chemical compound, drug",FITC-UEAI,ThermoFisher,L32476, "chemical

(7) Fatostatin ameliorates inflammation without affecting cell viabilityFEBS open bioMarch 1, 2022Ma S, Murakami K, Tanaka K, Hashimoto M, Tanaka M, Kitagori K, Akizuki S, Nakashima R, Yoshifuji H, Ohmura K, et al.Corp, Osaka, Japan), whereas those from the fatostatin group were injected with 0.6 mg of fatostatin (#13562; Cayman, Ann Arbour, MI, USA) in 80 µL of DMSO. Both groups were administered their respective injections

(8) Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in MyelomaCell metabolismJanuary 5, 2021Li Z, Liu H, He J, Wang Z, Yin Z, You G, Wang Z, Davis RE, Lin P, Bergsagel PL, et al.Proteins" DAPI,Sigma Aldrich,Cat# D9542 Cycloheximide,Cayman Chemical,Cat# 14126 Fatostatin,Cayman Chemical,Cat# 13562 Bafilomycin A1,Cayman Chemical,Cat# 11038 Leupeptin,Cayman Chemical,Cat# 14026 MG-132,R&D Systems INC

(9) Treg Cells Promote the SREBP1-Dependent Metabolic Fitness of Tumor-Promoting Macrophages via Repression of CD8⁺ T Cell-Derived Interferon-γImmunityAugust 20, 2019Liu C, Chikina M, Deshpande R, Menk AV, Wang T, Tabib T, Brunazzi EA, Vignali KM, Sun M, Stolz DB, et al.Recombinant Proteins","Chemicals, Peptides, and Recombinant Proteins" Fatostatin (hydrobromide),Cayman,Cat# 13562 "Collagenase, Type 4",Worthington Biochemical Corporation,Cat# CLS-4 Dispase,STEMCELL Technologies,Cat#

(10) Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic CancerCancer cellJanuary 1, 0001"Gabitova-Cornell L, Surumbayeva A, Peri S, Franco-Barraza J, Restifo D, Weitz N, Ogier C, Goldman AR, Hartman TR, Francescone R, et al."2005)",N/A Recombinant TGFβ1,Sigma,Cat#T7039 SB431542,Sigma,Cat#616464 Fatostatin,Cayman Chemical,Cat#13562 Matrigel Matrix,Corning,Cat#356234 Terra PCR Direct Red Dye Premix,TaKaRa,Cat#639286 GoTaq Green Master Mix

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Fatostatin (hydrobromide) from Cayman Chemical

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Cayman Chemical

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Fatostatin (hydrobromide) from Cayman Chemical

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