Deferoxamine (mesylate) from Cayman Chemical

Product Specs
ItemDeferoxamine (mesylate)
CompanyCayman Chemical
Price $590.00Supplier Page View Company Product Page
Catalog Number14595
Quantity5 g
Research AreaCell Biology, Cell Death, Ferroptosis
FormatA crystalline solid
Molecular Weight656.8
Purity≥95%
TypeInhibitors
OriginUSA
FormulaC25H48N6O8 • CH3SO3H
Storage-20

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Targeting oncogenic FLT3 uncovers a ferroptosis vulnerability through selenocysteine recoding in acute myeloid leukaemiaNat Cell BiolAugust 7, 2026Minhua Li, Yudan Zhu, Yuki Kageyama, Ken Furudate, Ayumi Kitano, Taotao Tan, Mengdie Feng, Jing Zhou, Tao Wang, Robert J. Taylor, et al.(Cayman Chemical, catalogue number 19288), deferoxamine (mesylate) (Cayman Chemical, catalogue number 14595) and liproxstatin-1 (MedChemExpress, HY-12726) were dissolved in tissue-culture-grade DMSO. Vector

(2) Iron Deficiency Impairs Mitochondrial Energetics and Early Axonal Growth and Branching in Developing Hippocampal NeuronsThe Journal of NutritionAugust 1, 2026List Daniel C Mendez, Karishma Devgun, Luke H. Carlson, Daniel J. Mickelson, Timothy R. Monko, Livia Reeves, Lorene M. Lanier, Michael K. Georgieff, Thomas W. Bastianone-time administration of 5μM of the extracellular iron chelator deferoxamine (DFO, Cayman Chemical #14595) for 24-well Seahorse XFe (Agilent Technologies) and 96-well plate or 9μM DFO for 35mm wells/dishes

(3) Timosaponin AIII inhibits gastric cancer growth by the promotion of programmed cell death via the activation of p300/acetyl-p53 and Akt/MEK/ERK signalingFront PharmacolJuly 20, 2026Kaizhen Tang, Wairong Zhao, Jing Zhang, Guangyu Wang, Wenting Shi, Meiyan Yue, Yan Lin, Yanli Fu, Zhongyan Zhouferrostatin-1 (catalog no. 17729), necrostatin-1 (catalog no. 11658) and deferoxamine (catalog no. 14595) were obtained from CAYMAN Chemical company. N-acetyl cysteine (NAC, catalog no. A9165) was obtained

(4) Double-bond geometry determines fatty acid metabolic fate and ferroptosis sensitivitybioRxivJuly 20, 2026Cynthia A. Harris, Shunji Kato, Yurika Otoki, Elisa Martin Martin Perez, Dylan Boone, Juan Lorenzo B. Pablo, Anna Greka, James A. Olzmann(#14463), Necrostatin-1 (#11658), Ferrostatin-1 (#17729), idebenone (#15475), deferoxamine mesylate (DFO, #14595), ML-162 (#20455), ML-210 (#23282), Erastin2 (#27087), Imidazole Ketone Erastin (IKE, #27088), L-Buthionine-(S,R)-Sulfoximine

(5) Ferroptosis is a Physiologic Vulnerability of Iron-Recycling MacrophagesbioRxivJune 29, 2026Miguel Mesquita, Maria Pires, Sara Violante, Jamil Zola Kitoko, Martim Costa, Sonia Trikha Rastogi, Rui Martins, Silvia Cardoso, Manuel Tanqueiro, Ana Figueiredo, et al.,Cayman Chemical,Cat#14463 Necrostatin-2 racemate (Nec-1),Selleckchem,Cat#S8641 Deferoxamine (DFO),Cayman Chemical,Cat#14595 LPS (ultrapure),InvivoGen,Cat#tlrl-3pelps Nigericin,Sigma-Aldrich,Cat# N7143 TNF (recombinant mouse),Gibco,Cat#315-01A RPMI

(6) FSP1 reduces exogenous coenzyme Q10 and inhibits ferroptosis to alleviate intestinal ischemia–reperfusion injuryJournal of Advanced ResearchJune 1, 2026Tianli Shen, Xingjie Wang, Junxiang Zhang, Yuyao Lin, Lindi Cai, Kai Deng, Cancan Zhou, Guanglin Qiu, Jie Lian, Qinhong Xu, et al.Caco2 cells. Idebenone (Cayman Chemical, 15475), Lip-1 (Selleckchem, S7699), DFO (Cayman Chemical, 14595) and iFSP (Selleckchem, S9663) were dissolved in DMSO at a stock concentration of 10 mM. 4-CBA (Sigma–Aldrich,

(7) Vitamin B2 metabolism promotes FSP1 stability to prevent ferroptosisNat Struct Mol BiolMarch 13, 2026Kirandeep K. Deol, Cynthia A. Harris, Sydney J. Tomlinson, Colin J. Delaney, Amr Al-Farhan, Alyssa J. Mathiowetz, Cody E. Doubravsky, Derek A. Pratt, James A. Olzmannand reagents We purchased 1S,3R-RSL3 (19288), FSEN1 (38025), Fer1 (17729), idebenone (15475), DFO (14595), ZVAD(OMe)-FMK (27421) and necrostatin 1 (11658) from Cayman Chemical. 3-Methyladenine (189490), Baf-A1,

(8) Hydrogen sulfide increases intracellular oxygen and inhibits the HIF responseThe Journal of biological chemistryMarch 1, 2026Brake J, Hanna DA, Kumar R, Peng Q, Landry AP, Singhal R, Weerapana E, Shah YM, Banerjee R.Clarity Western Enhanced Chemiluminescence Substrate (102032117 and 102032118) were from Bio-Rad. DFX (14595), bortezomib (10008822), and FG4592 (15294) were from Cayman. Phosphatase inhibitor cocktail (HY-K0021)

(9) Coenzyme A mitigates cystine‐deprivation‐induced ferroptosis by suppressing the iron‐starvation responseThe FEBS JournalJanuary 16, 2026Mingjun Tan, Yunzhan Li, Lei Sang, Min Wang, Qin Li, Zekun Li, Dongxiao Sun, Xiuchao Wang, Shengyu YangCoenzyme A (Cayman, Ann Arbor, MI, USA, 16147), D-Pantethine (Sigma, P2125), deferoxamine (Cayman, 14595), Ferrostatin-1 (Cayman, St. Louis, MO, USA, 17729), RSL3(Cayman, 19288), DTT (Sigma, D0632), 2-Mercaptoethanol

(10) Egg-derived sphingomyelin induces ferroptosis in cancer cells, depending on intracellular labile iron pool levelsBiochemistry and Biophysics ReportsDecember 1, 2025Chiharu Iwase, Atsushi Nishikawa, Chie Umatani, Yutaka MiuraMaterials SPM (#860061P) was purchased from Avanti Polar Lipids (Birmingham, UK). Deferoxamine mesylate (#14595) and ferrostatin-1 (#17729) were purchased from Cayman Chemical (Ann Arbor, MI, USA) and dissolved in

(11) FOXF1 and SHH participate in the regulation of iron signaling in pulmonary fibrosisRedox biologyNovember 1, 2025Wang X, Liu X, Fan Y, Tan K, Gao J, Wang Y, Zhang Z, Liu S, Wang X, Wang B, et al.mg/kg ferric ammonium citrate (FAC) (F5879, Sigma, Darmstadt, Germany) or 50 mg/kg deferoxamine (DFO) (14595, Cayman, Ann Arbor, USA) were administered to the corresponding groups of animals once daily by oral

(12) Iron Deficiency Impairs Mitochondrial Energetics and Early Axonal Growth and Branching in Developing Hippocampal NeuronsbioRxivOctober 18, 2025Daniel C. Mendez, Karishma Devgun, Timothy R. Monko, Luke H. Carlson, Daniel J. Mickelson, Lorene M. Lanier, Michael K. Georgieff, Thomas W. BastianDIV, ID was induced with 5μM of the extracellular iron chelator deferoxamine (DFO, Cayman Chemical #14595) for 24-well XFe (Agilent Technologies) and 96-well plate or 9μM DFO for 35mm dish (Bastian et al.,

(13) Heme and iron toxicity in the aged spleen impairs T cell immunity through iron deprivationNature AgingOctober 17, 2025David Ezuz, Heba Ombashe, Lana Watad, Akmaral Rakhymzhanova, Satyarth Pandey, Orna Atar, Esther G. Meyron-Holtz, Noga Ron-Harelwere supplemented with hemin chloride (Cayman, 16487), (1S,3 R)-RSL3 (Cayman, 19228), DFO (Cayman, 14595), Tin Mesoporphyrin IX (SnMP, Cayman, 19071), bovine serum albumin (BSA; Sigma-Aldrich, A9647), human

(14) Butyric acid and valeric acid attenuate stress-induced ferroptosis and depressive-like behaviors by suppressing hippocampal neuroinflammationJournal of Translational MedicineSeptember 2, 2025Xiaoying Ma, Weibo Shi, Zhen Wang, Shujin Li, Rufei Ma, Weihao Zhu, Lin Wu, Xiaowei Feng, Bin Cong, Yingmin Limice were treated with the ferroptosis inhibitors Fer-1 (17,729–10; Cayman Chemical, MI, USA) or DFO (14595-1; Cayman Chemical, MI, USA). Stock solutions of Fer-1 (10 mg/mL) and DFO (100 mg/mL) were prepared

(15) ALDH7A1 protects against ferroptosis by generating membrane NADH and regulating FSP1CellMay 15, 2025Jia-Shu Yang, Andrew J. Morris, Koki Kamizaki, Jianzhong Chen, Jillian Stark, William M. Oldham, Toshitaka Nakamura, Eikan Mishima, Joseph Loscalzo, Yasuhiro Minami, et al.,Cayman Chemicals,17754 Liproxstatin-1,Sigma-Aldrich,950455-15-9 Ferrostatin-1,Cayman Chemicals,17729 DFO,Cayman Chemicals,14595 FINO2,Cayman Chemicals,25096 Z-VAD-FMK,Cayman Chemicals,14467 Necrostatin-1,Cayman Chemicals,11658 4-HNE,Sigma-Aldrich,393204 MDA,Sigma-Aldrich,SMB00976 DTUN,Cayman Chemicals

(16) The Gut Microbiota Metabolite Butyrate Modulates Acute Stress-Induced Ferroptosis in the Prefrontal Cortex via the Gut-Brain AxisInt J Mol SciFebruary 17, 2025Zhen Wang, Xiaoying Ma, Weibo Shi, Weihao Zhu, Xiaowei Feng, Hongjian Xin, Yifan Zhang, Bin Cong, Yingmin Liadministered ferroptosis inhibitors Fer-1 (17729-10, Cayman Chemical, Ann Arbor, MI, USA) and DFO (14595-1, Cayman Chemical, Ann Arbor, MI, USA). To prepare the solutions, the co-solvent dimethyl sulfoxide

(17) Conjugated fatty acids drive ferroptosis through chaperone-mediated autophagic degradation of GPX4 by targeting mitochondriaCell Death & DiseaseDecember 6, 2024Yusuke Hirata, Yuto Yamada, Soma Taguchi, Ryota Kojima, Haruka Masumoto, Shinnosuke Kimura, Takuya Niijima, Takashi Toyama, Ryoji Kise, Emiko Sato, et al.Triacsin C (#10007448), PF-04620110 (iDGAT1, #16425), PF-06424439 (iDGAT2, #17680), deferoxamine (DFO, #14595), Perhexiline (#16982), 2-cyano-3, 12-dioxooleana-1, 9(11)-dien-28-oate (CDDO, #81035) (Cayman, Ann

(18) SAT1/ALOX15 Signaling Pathway Is Involved in Ferroptosis After Skeletal Muscle ContusionInternational Journal of Molecular SciencesOctober 21, 2024Huihuang Yang, Yingmin Li, Weihao Zhu, Xiaowei Feng, Hongjian Xin, Hao Chen, Guozhong Zhang, Min Zuo, Bin Cong, Weibo ShiD0798), Ferrostatin-1 (Cayman Chemical, Ann Arbor, MI, USA, 17729), and Deferoxamine (Cayman Chemical, 14595) were dissolved in DMSO at a concentration of 5 mg/mL. (1S,3R)-RSL3 (Cayman Chemical, 19288) was dissolved

(19) Intracellular Iron Deficiency and Abnormal Metabolism, Not Ferroptosis, Contributes to Homocysteine-Induced Vascular Endothelial Cell DeathBiomedicinesOctober 10, 2024Wenting Shi, Jing Zhang, Wairong Zhao, Meiyan Yue, Jie Ma, Silu Zeng, Jingyi Tang, Yu Wang, Zhongyan ZhouZ-VDA(OH)-FMK (Cat. No. 14467), ferrostatin-1 (Fer-1, Cat. No. 17729), and deferoxamine (DFO, Cat. No. 14595) were obtained from Cayman chemical (Ann Arbor, Michigan, USA). TriPure Isolation Reagent (Cat. No.

(20) N-Myristoytransferase Inhibition Causes Mitochondrial Iron Overload and Parthanatos in TIM17A-Dependent Aggressive Lung CarcinomaCancer Res CommunJuly 1, 2024Sofia Geroyska, Isabel Mejia, Alfred A. Chan, Marian Navarrete, Vijaya Pandey, Samuel Kharpatin, Juliana Noguti, Feng Wang, Daniel Srole, Tsui-Fen Chou, et al.(cat. no. HY-147308), and IMP-1088 was from Cayman Chemical (cat. no. 25366). Deferoxamine (cat. no. 14595), ferrostatin-1 (cat. no. 17729) liproxstatin-1 (cat. no. 17730), erastin (cat. no. 17754), trolox (cat.

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Deferoxamine (mesylate) from Cayman Chemical

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Cayman Chemical

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Deferoxamine (mesylate) from Cayman Chemical

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