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Protein Biochemistry
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Lonidamine
Lonidamine from Cayman Chemical
Be the first to write a review!
Citations:
(5)
Supplier Page
Supplier Page from
Cayman Chemical for
Lonidamine
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Description
Inhibits glycolysis though the inactivation of mitochondria-bound hexokinase; decreases oxygen consumption as well as aerobic and anaerobic glycolysis in Ehrlich ascites tumor cells (IC50s = 90 and 45 µM, respectively)
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Lonidamine
Company
Cayman Chemical
Price
$54.00
Supplier Page
View Company Product Page
Catalog Number
14640
Quantity
5 mg
Format
A crystalline solid
Molecular Weight
321.2
Purity
≥98%
Type
Inhibitors
Research Area
Cancer, Carbohydrate Metabolism, Diabetes, Endocrinology & Metabolism, Metabolic Diseases, Metabolism, Neuroscience, Obesity
Storage
-20
Formula
C15H10Cl2N2O2
Origin
CHN
Add to Compare List
Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (5)
(1)
Therapeutic Targeting of Microglial Hexokinase-2 Recalibrates Inflammasome Activation and Improves Functional Recovery After Traumatic Brain Injury
bioRxiv
March 3, 2026
Claudia Mera-Reina, Juan F. Codocedo, Paul B. Fallen, Jack Scott, Cristian A. Lasagna-Reeves, Gary E. Landreth
viability before experimental use. Drug Treatments
Lonidamine
(LND) was purchased from
Cayman Chemicals
(
14640
), and a stock solution was prepared in DMSO (
Sigma
D2650
). The daily dose of LND was 50 mg/kg
body weight
,
(2)
Therapeutic targeting of immunometabolism in Alzheimer’s disease reveals a critical reliance on Hexokinase 2 dosage on microglial activation and disease progression
bioRxiv
November 18, 2023
Juan F. Codocedo, Claudia Mera-Reina, Peter Bor-Chian Lin, Shweta S. Puntambekar, Brad T. Casali, Nur Jury, Pablo Martinez, Cristian A. Lasagna-Reeves, Gary E. Landreth
performed. Experiments always used littermate controls.
Lonidamine
was purchased from
Cayman
Chemicals (
14640
) and stock solution was prepared in DMSO (
Sigma
D2650
). The daily dose of LND used was 50 mg/kg
body weight
(3)
Lonidamine and domperidone inhibit expansion of transformed cell areas by modulating motility of surrounding nontransformed cells
The Journal of biological chemistry
December 1, 2022
Aoyama M, Ishikawa K, Nemoto S, Hirano H, Watanabe N, Osada H, Watanabe S, Semba K.
using Opti-MEM (
31985
-070) and PEI (#
24765
-2). Chemical reagents DPD (
18875
), pimozide (
16222
), LND (
14640
), and
UK-5099
(
16980
) were purchased from
Cayman Chemical
.
Haloperidol
(084-04261), 3,4-dihydroxyphenethylamine
(4)
Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
Cancer cell
September 14, 2020
Chung C, Sweha SR, Pratt D, Tamrazi B, Panwalkar P, Banda A, Bayliss J, Hawes D, Yang F, Lee HJ,
et al
.
16366
CB-839
,
Cayman
Chem.,Cat#
22038
BPTES
,
Cayman
Chem.,Cat#
19284
Lonidamine
,
Cayman
Chem.,Cat#
14640
Ketoconazole
,
Cayman
Chem.,Cat#
15212
Posaconazole
,
Cayman
Chem.,Cat#
14737
Desferrioxamine,
Cayman
(5)
TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy
Cell metabolism
January 8, 2019
Li L, Liu X, Sanders KL, Edwards JL, Ye J, Si F, Gao A, Huang L, Hsueh EC, Ford DA,
et al
.
SuperScript II Reverse Transcriptase
,
Invitrogen
,Cat#
18064014
Phloretin
,
Cayman Chemical
,Cat#
14452
; CAS:60–82-2 LND,
Cayman Chemical
,Cat#
14640
; CAS:50264–69-2 2-DG,
Cayman Chemical
,Cat#
14325
; CAS:154–17-6 3-BrPA,
Cayman Chemical
,Cat#
19068
; CAS:1113–59-3 Etomoxir,
Cayman Chemical
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Lonidamine from Cayman Chemical
Supplier Page
View Company Product Page
$54.00
Product Specs
Company Info
Citations
Reviews
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