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Protein Biochemistry
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ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist
ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist from Abcam
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Citations:
(3)
Supplier Page
Supplier Page from
Abcam for
ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist
Description
Selective protease-activated receptor 2 (PAR2) anatagonist
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist
Company
Abcam
Price
Supplier Page
View Company Product Page
Catalog Number
ab141699
Quantity
5 mg, 25 mg
Purity
0.99
Type
Activator/Agonist
Molecule Name
6-Amino-1-[4-(3-methylbutanoyl)piperazin-1-yl]hexan-1-one
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Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (3)
(1)
Critical role of keratinocytes and protease-activated receptor 2 in secondary lymphedema development
Clin Transl Med
June 1, 2026
Hyeung Ju Park, Sarit Pal, Xizhao Chen, Jinyeon Shin, Gabriela D. García Nores, Jung Eun Baik, Annica Stull-Lane, Abraham J. Book, Cristina C. Clement, Elizabeth M. Encarnacion,
et al.
with or without 10%
lymphedema
fluid in
keratinocyte
medium. 10 µg/mL ENMD1068, a
PAR2
antagonist (
ab141699
;
Abcam
), was added once to the culture media at the same time as the
lymphedema
fluid treatment. TF
(2)
Neutrophil-derived serine proteases induce FOXA2-mediated autophagy dysfunction and exacerbate colitis-associated carcinogenesis via F2RL1/protease-activated receptor 2
Autophagy
October 3, 2025
Junhu Yuan, Jianhui Ma, Fanyu Zhang, Tan Wang, Xiaxiang Jian, Bingzhi Wang, Weiwei Li, Xiaoli Zhang, Yubin Cao, Hong Yang,
et al.
F2RL1/PAR2-IN-1 (
MedChemExpress
,
HY-138558
), F2RL1/PAR2-AP (Shanghai Apeptide, N/A),
ENMD-1068
(
Abcam
,
ab141699
), mitoSox Green (Thermo Scientific, M36005), Lipofectamine 2000 (
Thermo Scientific
11668019
), DAPI (Sigma-Aldrich,
(3)
The antiprotease Spink7 promotes inflammation resolution by modulating multiple proteases activities during wound healing
Clin Transl Med
March 27, 2025
Na Zhao, Guojian Wang, Shuang Long, Xiaofan Lv, Xinze Ran, Junping Wang, Yongping Su, Tao Wang
activation in impaired
wound
healing of
Spink7
KO
mice
, the treatment of specific antagonist
ENMD‐1068
(
ab141699
,
Abcam
) was performed in murine
wound
healing in vivo model.
ENMD‐1068
was administrated every day from
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ENMD-1068, protease-activated receptor 2 (PAR2) anatagonist from Abcam
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