Cyclophosphamide (hydrate) from Cayman Chemical

Product Specs
ItemCyclophosphamide (hydrate)
CompanyCayman Chemical
Price $176.00Supplier Page View Company Product Page
Catalog Number13849
Quantity10 g
Research AreaAdaptive Immunity, Autoimmunity, Cancer, Cell Death, Cytochrome P450s, Developmental, DNA Alkylating Agents, DNA Damage and Repair, Hepatotoxicity, Immunology & Inflammation, Immunosuppressants, Nephrotoxicity, Organ- & System-Specific Toxicity, Toxicology & Xenobiotic Metabolism
FormatA crystalline solid
Molecular Weight279.1
Purity≥98%
Storage-20
FormulaC7H15Cl2N2O2P • H2O
OriginCHN
Source/Expression SystemSynthetic
TypeInhibitors

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Ionizing radiation enhances CAR T-cell infiltration and efficacy in solid tumorsFront ImmunolApril 15, 2026Lisa Zhan, Meredith A. Clark, Pauline Loos, Che-Min Lee, Laura E. R. Paulus, Rocky Shi, Prabhreet K. Sekhon, James M. Piret, Laura Evgin, Kevin L. Bennewithlymphodepleted via an intraperitoneal (i.p.) injection of filter-sterilized 200 mg/kg cyclophosphamide (CTX) (13849; Cayman Chemical, Ann Arbor, MI, USA) dissolved in sterile 0.9% NaCl. Tumor irradiations were performed

(2) Preconditioning with Low-Dose Radiation Improves Antitumor Immunity and Survival in DC-Vaccinated MiceLife (Basel)September 4, 2025Eric Kwon, Shelby Namen, Colin J. Willoughby, Solomon Kang, Gaurav Pandey, Alexander B. Kim, Carl J. DeSelmplaced over the animal to ensure no dose to the total body. 2.3. Chemotherapy Cyclophosphamide (Cat. 13849, Cayman Chemical, Ann Arbor, MI, USA) was resuspended in PBS and injected at 250 mg/kg [15]. Paclitaxel

(3) Targeting CD117 on hematopoietic stem and progenitor cells impairs CAR T cell activityMolecular therapy : the journal of the American Society of Gene TherapySeptember 3, 2025Thomas R, Ritchey JK, DiPersio JF, Kim MY.106 9523CD19 cells on day −3 or day −4, followed by intraperitoneal (i.p.) injection of Cy (Cayman, 13849) 250 mg/kg on day −1, then injected i.v. with UTD, mCART19, or mCART117 (manufactured from CD45.1+ C57BL/6

(4) Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironmentImmunityJuly 8, 2025William D. Green, Amber Gomez, Alec L. Plotkin, Brandon M. Pratt, Emily F. Merritt, Genevieve N. Mullins, Nancy P. Kren, Jennifer L. Modliszewski, Vasyl Zhabotynsky, Mark G. Woodcock, et al.LDEV-free,Corning,Cat#356234 Meloxicam,Patterson Veterinary,Cat#07-893-7565 Cyclophosphamide (hydrate),Cayman,Cat# 13849 BD Horizon Brilliant Stain Buffer,BD Biosciences,Cat#566349 Prolong Gold,Invitrogen,Cat#P36930 APC

(5) Lymph node macrophages drive immune tolerance and resistance to cancer therapy by induction of the immune-regulatory cytokine IL-33Cancer CellMay 12, 2025Sara Lamorte, Rene Quevedo, Robbie Jin, Luke Neufeld, Zhe Qi Liu, M. Teresa Ciudad, Sabelo Lukhele, Jessica Bruce, Shreya Mishra, Xin Zhang, et al.,New England BioLabs,Cat#M0535 Puromycin,Millipore-Sigma,Cat#P8833 Cisplatin,Millipore-Sigma,Cat#P4394 PLX4720,Cayman Chemical Company,Cat#15142 Cyclophosphamide,Cayman Chemical Company,Cat#13849 TNF,Peprotech,Cat#315-01A SM-164,MedChem Express,Cat# HY15989 Z-VAD-FMK,Invitrogen,Cat#tlr-vad Flagellin,Invitrogen,Cat#

(6) Fungal symbiont transmitted by free-living mice promotes type 2 immunityNatureDecember 19, 2024Yun Liao, Iris H. Gao, Takato Kusakabe, Woan-Yu Lin, Alexander Grier, Xiangyu Pan, Olga Morzhanaeva, Terrance P. Shea, Hiroshi Yano, Danielle Karo-Atar, et al.three times, followed by intraperitoneal injection of 150 mg/kg mouse weight of cyclophosphamide (Cat#13849, Cayman) on days 0, 2, and 4. The survival data were recorded, and the kidney was collected for CFU

(7) Impact of immunosuppressive drugs on efficacy of mesenchymal stem cell therapy for suppressing renal fibrosisStem Cells Translational MedicineNovember 12, 2024Kisho Miyasako, Ayumu Nakashima, Naoki Ishiuchi, Yoshiki Tanaka, Keisuke Morimoto, Kensuke Sasaki, Shogo Nagamatsu, Go Matsuda, Takao Masakimg/kg; Cat# 15013, Cayman Chemical, Ann Arbor, MI, USA, Cat# 031-24931, Wako, Osaka, Japan and Cat# 13849, Cayman Chemical, respectively) were injected intraperitoneally at UUO day 3 in all groups, except the

(8) IL-3-driven T cell–basophil crosstalk enhances antitumor immunityCancer Immunology ResearchJuly 2, 2024Jian Wei, Colleen L. Mayberry, Xiaoting Lv, Fangyan Hu, Taushif Khan, Natalie A. Logan, John J. Wilson, John D. Sears, Damien Chaussabel, Chih-Hao Changchemotherapy treatment, activated T cells were incubated with cyclophosphamide (CTX, Cayman Chemical, 13849) at a concentration of 12 μM from day 2 to day 3 post-stimulation. For low glucose treatment, glucose-free

(9) IL-3-driven T cell–basophil crosstalk enhances antitumor immunityCancer Immunol ResJuly 2, 2024Jian Wei, Colleen L. Mayberry, Xiaoting Lv, Fangyan Hu, Taushif Khan, Natalie A. Logan, John J. Wilson, John D. Sears, Damien Chaussabel, Chih-Hao Changchemotherapy treatment, activated T cells were incubated with cyclophosphamide (CTX, Cayman Chemical, 13849) at a concentration of 12 μM from day 2 to day 3 post-stimulation. For low glucose treatment, glucose-free

(10) Validation of a mouse 3D gastruloid-based embryotoxicity assay in reference to the ICH S5(R3) guideline chemical exposure listReproductive ToxicologyApril 1, 2024Margaret Carrell Huntsman, Courtney Kehaulani Kurashima, Yusuke Marikawa(DMSO) Cetirizine,,Cayman (19686),100 mM (DMSO) Cisplatin,,Cayman (13119),50 mM (DMSO) Cyclophosphamide,,Cayman (13849),100 mM (DMSO) Cytarabine,Cytosine β-D-arabinofuranosidea,Sigma (C1768),50 mM (H2O) Dabrafenib,,Cayman

(11) A long-acting interleukin-7, rhIL-7-hyFc, enhances CAR T cell expansion, persistence, and anti-tumor activityNature communicationsJune 13, 2022Kim MY, Jayasinghe R, Devenport JM, Ritchey JK, Rettig MP, O'Neal J, Staser KW, Kennerly KM, Carter AJ, Gao F, et al.104 9523CD19 cells on day −3, followed by intraperitoneal (IP) injection of cyclophosphamide (Cayman, 13849) 250 mg/kg on day −1, then injected IV with 6 × 106 UTD or mCART19 (manufactured from CD45.1+ C57BL/6

(12) DectiSomes: Glycan Targeting of Liposomal Drugs Improves the Treatment of Disseminated CandidiasisAntimicrobial Agents and ChemotherapyJanuary 18, 2022Suresh Ambati, Tuyetnhu Pham, Zachary A. Lewis, Xiaorong Lin, Richard B. Meagherneutropenic mice were obtained by treatment with both the antimetabolite cyclophosphamide (CP, Cayman #13849) and the synthetic steroid triamcinolone (TC, Millipore Sigma # T6376) following the schedules shown

(13) DectiSomes: Glycan Targeting of Liposomal Drugs Improves the Treatment of Disseminated CandidiasisAntimicrob Agents ChemotherOctober 11, 2021Suresh Ambati, Tuyetnhu Pham, Zachary A. Lewis, Xiaorong Lin, Richard B. Meagherneutropenic mice were obtained by treatment with both the antimetabolite cyclophosphamide (CP, Cayman #13849) and the synthetic steroid triamcinolone (TC, Millipore Sigma # T6376) following the schedules shown

(14) Antifungal Liposomes Directed by Dectin-2 Offer a Promising Therapeutic Option for Pulmonary AspergillosismBioFebruary 24, 2021Suresh Ambati, Emma C. Ellis, Tuyetnhu Pham, Zachary A. Lewis, Xiaorong Lin, Richard B. Meagherantimetabolite cyclophosphamide (CP) in addition to TC (Fig. S1). A cyclophosphamide (Cayman cat. no. 13849) stock of 35 mg/ ml was prepared in saline, pH 7.4, ﬁlter sterilized, and delivered subcutaneously at 175

(15) Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and RelapseCancer cellSeptember 16, 2019Zhang L, He X, Liu X, Zhang F, Huang LF, Potter AS, Xu L, Zhou W, Zheng T, Luo Z, et al.LLC",Cat# 315110 Cisplatin,Cayman Chemical,Cat# 13119 Cyclophosphamide (hydrate),Cayman Chemical,Cat# 13849 Palbociclib,LC Labs,Cat# P-7788 Bupivicaine,Hospira,Cat# 00409361301 CD532,Millipore,Cat# 532605 Red

(16) Metformin inhibits metastatic breast cancer progression and improves chemosensitivity by inducing vessel normalization via PDGF-B downregulationJournal of experimental & clinical cancer research : CRJune 4, 2019Wang JC, Li GY, Wang B, Han SX, Sun X, Jiang YN, Shen YW, Zhou C, Feng J, Lu SY, et al.(6 cm diameter) each day. Chemicals and reagents Metformin (No.13118), cyclophosphamide (CTX, No.13849), cisplatin (CPT, No.13119) and imatinib (No.13139) were purchased from Cayman Chemical. The active

(17) Mast Cells Are Mediators of Fibrosis and Effector Cell Recruitment in Dermal Chronic Graft-vs.-Host DiseaseFrontiers in immunologyJanuary 1, 2019Strattan E, Palaniyandi S, Kumari R, Du J, Hakim N, Huang T, Kesler MV, Jennings CD, Sturgill JL, Hildebrandt GC.chemotherapeutic agents. Busulfan and cyclophosphamide were purchased from Cayman Chemicals (14843 and 13849, Ann Arbor, MI) and resuspended in DMSO. Drugging time and conditions were chosen based on clinical

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Cyclophosphamide (hydrate) from Cayman Chemical

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Cayman Chemical

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Cyclophosphamide (hydrate) from Cayman Chemical

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