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Protein Biochemistry
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PP1 (Src Inhibitor)
PP1 (Src Inhibitor) from Cayman Chemical
Be the first to write a review!
Citations:
(7)
Supplier Page
Supplier Page from
Cayman Chemical for
PP1 (Src Inhibitor)
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Description
A potent, reversible, ATP-competitive, and selective inhibitor of the Src family of protein tyrosine kinases: p56lck (IC50 = 5 nM), p59fynT (IC50 = 6 nM), Hck (IC50 = 20 nM)
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
PP1 (Src Inhibitor)
Company
Cayman Chemical
Price
$132.00
Supplier Page
View Company Product Page
Catalog Number
14244
Quantity
5 mg
Research Area
Apoptosis, Cancer, Cell Death, Cell Signaling, SRC Family Signaling
Format
A crystalline solid
Molecular Weight
281.4
Purity
≥98%
Storage
-20
Formula
C16H19N5
Origin
CHN
Type
Inhibitors
Add to Compare List
Cayman Chemical
Cayman Chemical Company 1180 East Ellsworth Road
Ann Arbor
,
Michigan
48108
United States
Phone
: (800) 364-9897
(734) 971-3640
Company Profile
Website:
http://www.caymanchem.com/
Citations (7)
(1)
Submicron-Sampling of Living Cells by Macrophages
bioRxiv
December 2, 2025
Amy C. Fan, Rukman Thota, Nina Serwas, Vivasvan S. Vykunta, Kyle Marchuk, Megan K. Ruhland, Lauren Liu, Grace Johnson, Austin Edwards, Matthew F. Krummel
for MEF-ZsGreen at 0 h. Signaling and
cytoskeleton
inhibition was performed using 10 μM PP1 (
Cayman
#
14244
), 5 μM Piceatannol (
MedChemExpress
#
HY-13518
), 10 μM
GDC-0941
(
Selleck Chemicals
#
S1065
), 1.35 μM
NAV-2729
(2)
CSF1R-CAR T cells induce CSF1R signaling and can promote target cell proliferation
Science Signaling
November 11, 2025
Aurora Callahan, Xinyan Zhang, Amber Wang, Aisharja Mojumdar, Longhui Zeng, Xiaolei Su, Arthur R. Salomon
unsupplemented RPMI 1640, and then suspended in RPMI 1640 supplemented with PP1 (
Cayman Chemical Company
#
14244
),
Cytochalasin D
(
Cayman Chemical Company
#
11330
), or DMSO (Fisher Scientific #BP231–100) at a concentration
(3)
Concerted localization-resets precede YAP-dependent transcription
Nature communications
September 11, 2020
Franklin JM, Ghosh RP, Shi Q, Reddick MP, Liphardt JT.
stock. Cells were treated
at 1
μM and imaged immediately. Src inhibitor (PP1):
Cayman Chemical Company
—#
14244
. Ten millimolar DMSO stock. Cells were treated at 10 μM and imaged after 1 hr for
YAP
fluctuation experiments
(4)
Endothelial microvesicles carrying Src-rich cargo impair adherens junction integrity and cytoskeleton homeostasis
Cardiovascular research
July 1, 2020
Chatterjee V, Yang X, Ma Y, Cha B, Meegan JE, Wu M, Yuan SY.
antibody (Cat #
ab9535
) were from
Abcam
(Cambridge, MA, USA). Thrombin (Cat # 9002-04-4) and PP1 (Cat #
14244
) were from
Cayman Chemical
(Ann Arbor, MI, USA).
Human
recombinant C5a (Cat #
2037-C5-025
) was from
(5)
Case report for an adolescent with germline RET mutation and alveolar rhabdomyosarcoma
Cold Spring Harbor molecular case studies
June 1, 2020
Crawford KA, Berlow NE, Tsay J, Lazich M, Mancini M, Noakes C, Huang T, Keller C.
MultiFlo dispenser. Cultures were grown overnight and then treated with drugs
FGF401
(
23029
), PP1 (
14244
),
Ruxolitinib
(
11609
), and
Stattic
(
14590
) that were all purchased from
Cayman Chemical
. All of the
(6)
Septins suppress the release of vaccinia virus from infected cells
The Journal of cell biology
August 6, 2018
Pfanzelter J, Mostowy S, Way M.
concentration of 100 µM after 7 h of
infection
for 1 h before fixation.
PP1
was obtained from
Cayman Chemical
(
14244
) and added to a final concentration of 12.5 µM after 4 h of
infection
for an additional 4 h before fixation.
(7)
Inverted formin 2 regulates intracellular trafficking, placentation, and pregnancy outcome
eLife
January 8, 2018
Lamm KYB, Johnson ML, Baker Phillips J, Muntifering MB, James JM, Jones HN, Redline RW, Rokas A, Muglia LJ.
PLGF
Quantikine ELISA Kit,
R and D Systems
DPG00
,N/A "Chemical compound, drug",PP1,
Cayman Chemical
14244
CAS: 172889-26-8,N/A "Chemical compound, drug",TX1123,MilliporeSigma 655200 CAS: 157397-06-3,N/A "Software,
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PP1 (Src Inhibitor) from Cayman Chemical
Supplier Page
View Company Product Page
$132.00
Product Specs
Company Info
Citations
Reviews
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