XAV939, Tankyrase inhibitor from Abcam

Product Specs
ItemXAV939, Tankyrase inhibitor
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab120897
Quantity5 mg, 10 mg, 25 mg
TypeInhibitor, inhibitor
Molecule NameXAV939, Tankyrase inhibitor

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Abcam

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Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) Aberrant lipid metabolism renders an aggressive behavior of T-lymphoblastic lymphoma in a MASH modelOncogeneNovember 26, 2025Wei Guo, Xingtong Wang, Guozhen Cui, Emily A. S. Schmieder, Yonglin Gao, Butian Zhang, Robert C. G. Martin, Ou Bai, Yan LiThe in vitro treatments were the following: rhFGF21 (PeproTech, 100-42) at 100 ng/mL, XAV939 (Abcam, ab120897) at 1 μM, LiCl (Sigma-Aldrich, L9650) at 20 mM, and fenofibrate (Sigma, F6020-5G) at 100 µM. All the

(2) A scalable platform for EPSC-Induced MSC extracellular vesicles with therapeutic potentialStem Cell Res TherAugust 5, 2025Shixin Gong, Nan Li, Qinqing Peng, Feng Wang, Rulong Du, Boyang Zhang, Jian Wang, Le Han, Yu Zhang, Zemin Ning, et al.minocycline hydrochloride (2µM, MEC, HY-17412), Y-27,632 (2µM, Abcam, ab120129),XAV939 (2µM, Abcam, ab120897) and Human Recombinant Activin A (40 ng/mL, Stemcell Technologies, 78001). Induction of trophoblast-like

(3) Hypomethylation-enhanced CRTC2 expression drives malignant phenotypes and primary resistance to immunotherapy in hepatocellular carcinomaiScienceJune 21, 2024Zhang R, Dai J, Yao F, Zhou S, Huang W, Xu J, Yu K, Chen Y, Fan B, Zhang L, et al.were purchased from Jackson (USA). The following chemicals were used for cell pretreatment: XAV-939 (Ab120897, Abcam, UK); 5-Aza-dC (2353-33-5, Sigma-Aldrich, USA). Cell transfection and treatment GeneChem (Shanghai,

(4) Rat post-implantation epiblast-derived pluripotent stem cells produce functional germ cellsCell Rep MethodsAugust 28, 2023Iwatsuki K, Oikawa M, Kobayashi H, Penfold CA, Sanbo M, Yamamoto T, Hochi S, Kurimoto K, Hirabayashi M, Kobayashi T.Recombinant Human FGF-basic,Peprotech,Cat# 100-18B IWP2,Tocris Bioscience,Cat# 3533; CAS: 686770-61-6 XAV939,Abcam,Cat# ab120897; CAS: 284028-89-3 Y-27632 dihydrochloride,Tocris Bioscience,Cat# 1254; CAS: 129830-38-2 CHIR 99021,Axon

(5) Long non‑coding RNA MALAT1 suppresses the proliferation and migration of endothelial progenitor cells in deep vein thrombosis by regulating the Wnt/β‑catenin pathwayExperimental and Therapeutic MedicineJuly 28, 2020Binghui Du, Jian Wang, Sheng Zang, Xin Mao, Yaming Dutranscription-quantitative PCR (RT-qPCR). The Wnt/β-catenin signaling inhibitor XAV939 (10 nM; cat. no. ab120897; Abcam) was used to treat si-MALAT1-transfected cells. All transfections were performed using Lipofectamine®

(6) Mesenchymal-epithelial transition regulates initiation of pluripotency exit before gastrulationDevelopment (Cambridge, England)February 3, 2020Hamidi S, Nakaya Y, Nagai H, Alev C, Kasukawa T, Chhabra S, Lee R, Niwa H, Warmflash A, Shibata T, et al.Systems, 338-AC), 5 ng/ml human recombinant FGF2 (R&D Systems, 3139-FB) and 10 µM of XAV939 (Abcam, ab120897). Cells were passaged every 4-5 days using accutase for single cell dissociation. Laser microdissection hiPSC

(7) Asporin Reduces Adult Aortic Valve Interstitial Cell Mineralization Induced by Osteogenic Media and Wnt Signaling Manipulation In VitroInternational journal of cell biologyJanuary 1, 2020Polley A, Khanam R, Sengupta A, Chakraborty S.activation assay. Similarly, cultured cells were treated with Xav939, also for 24 hrs (2 μM; Abcam ab120897) for Wnt signaling inhibition assay [19, 21]. After completion of all the treatments, experiments were

(8) A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identityNature communicationsJune 15, 2016Fagnocchi L, Cherubini A, Hatsuda H, Fasciani A, Mazzoleni S, Poli V, Berno V, Rossi RL, Reinbold R, Endele M, et al.AG490 (Invivogen, cat. N°tlrl-ag4); 1 μM Jak1 (Millipore, cat. N°420099); 3 μM XAV939 (AbCam, cat. N°ab120897). RNA extraction and analysis Total RNAs were isolated from biological triplicates of ES cell cultures

(9) Glycoprotein (GP)96 Is Essential for Maintaining Intestinal Epithelial Architecture by Supporting Its Self-Renewal CapacityCellular and molecular gastroenterology and hepatologyJanuary 1, 0001"Häfliger J, Schwarzfischer M, Atrott K, Stanzel C, Morsy Y, Wawrzyniak M, Lang S, Valenta T, Basler K, Rogler G, et al."5 μmol/L CHIR99021 (CHIR) (4423/10; Tocris), 10 μmol/L DAPT (2634; Tocris), 10 μmol/L XAV939 (XAV) (ab120897; Abcam), or 1 mmol/L VPA (2815; Tocris). At the indicated times, organoids were collected and processed

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XAV939, Tankyrase inhibitor from Abcam

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XAV939, Tankyrase inhibitor from Abcam

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