Description
ML335 (CYM 51010, CID-23723457) is an agonist for OPRM1(u-opioid receptor)-OPRD1(delta-opioid receptor) heterodimerization with EC50 of 403 nM demonstrating selectivity over the individual OPRM1 and OPRD1 receptors and the serotonin HT5A receptor with EC50 of 14.9 uM, 1.1 uM, and >40 uM, respectively