Description
Dextran sulfates are produced by sulfation of selected dextran fractions.The dextran sulfate is supplied as the sodium salt and is stabilised by a small addition of phosphate salts. A certificate of analysis is supplied with each batch. The molecular weight range, sulfur content, moisture etc. are carefully controlled.StructureDextran is a polysaccharide derived from the bacterium Leuconostoc mesenteroides B512F and consists of an α-D-(1 – 6) linear glucan with a low content (ca. 5%) of sidechains linked to the 3-carbon of glucose. Dextran sulfate is a sulfated derivative of selected dextran fraction. The degree of sulfatation of our high sulfated dextran sulfates lies between 16 to 20 %.ApplicationsDextran sulfate have a wide range of applications areas and properties. Some examples are:Anti-coagulation agent in cell mediaSelective precipitation of lipoproteinsAcceleration of DNA hybridisation.Releasing DNA from DNA-histones complexesInhibition tRNA-binding to ribosomesInhibition of ribonucleasesAnti-viral propertiesUsed in cosmetics for anti-inflammation properties and osmotic retention of waterSeparation of microorganisms and macromoleculesAdjuvant in vaccinesStudies of perm selectivity of membranes