Description
eIF4A3-IN-13 (compound 75) is a silvestrol analogue. eIF4A3-IN-13 interferes the assembling of eIF4F translation complex with EC 50 s of 0.6, 15 and 0.4 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-13 can be used for the research of human cancer pathogenesis.Form:Solid